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Injection for treating pile and fistula and its preparing process

A technology for injecting liquid and hemorrhoid fistula, applied in the direction of sulfur/selenium/tellurium active ingredients, cardiovascular system diseases, drug combination, etc., can solve the problems that are not suitable for large-scale industrial production and unsafe production, and achieve easy industrialization Large-scale production, safe production process, and good efficacy

Inactive Publication Date: 2002-11-27
葫芦岛国帝药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The anesthesia ether in the injection solution for treating hemorrhoids is also extremely flammable during the production process, and there are serious production unsafe factors, so it is not suitable for industrialized large-scale production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] The injection solution for treating hemorrhoids consists of 30 grams of sodium sulfide, 5 grams of menthol, 30 ml of cosolvent (propylene glycol or Tween-80), 2 grams of glycerin, 100 ml of ethanol and 1000 ml of water for injection.

[0014] Its preparation process is:

[0015] Take the dosed ethanol and water for injection to prepare an ethanol solution, dissolve sodium sulfide in an appropriate amount of ethanol solution, add glycerin and stir to dissolve. Take an appropriate amount of ethanol solution and co-solvent and add menthol to dissolve it; mix the above two solutions and add ethanol solution to 1000 ml, stir until clear, measure the pH value of 6-14, the content, then filter and pot.

Embodiment 2

[0017] The injection solution for treating hemorrhoids consists of 120 grams of sodium sulfide, 50 grams of menthol, 150 ml of cosolvent (propylene glycol or Tween-80), 100 grams of glycerin, 800 ml of ethanol and 1000 ml of water for injection.

[0018] Take the dosed ethanol and water for injection to prepare an ethanol solution, dissolve sodium sulfide in an appropriate amount of ethanol solution, add glycerin and stir to dissolve. Take an appropriate amount of ethanol solution and co-solvent and add menthol to dissolve it; mix the above two solutions and add ethanol solution to 1000 ml, stir until clear, measure the pH value of 6-14, the content, then filter and pot.

Embodiment 3

[0020] The injection solution for treating hemorrhoids consists of 100 grams of sodium sulfide, 30 grams of menthol, 120 ml of propylene glycol, 10 grams of glycerin, 700 milliliters of ethanol and 1000 milliliters of water for injection.

[0021] The preparation process is as follows: taking dosed ethanol and water for injection to prepare an ethanol solution, dissolving sodium sulfide in an appropriate amount of ethanol solution, adding glycerin and stirring to dissolve. Take an appropriate amount of ethanol solution and propylene glycol (co-solvent) and add menthol to dissolve it; mix the above two solutions and add ethanol solution to 1000 ml, stir until clear, measure the pH value of 6-14, the content, then filter, potting.

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PUM

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Abstract

An injection for treating pile and fistula is prepared through preparing alcohol solution from alcohol and the water for injection, dissolving sodium sulfide in it, adding glycerin, stirring to obtain a solution, mixing alcohol solution with cosolvent, dissolving menthol, and mixing it with above-mentioned solution, adding alcohol solution, stirring until it becomes transparent, measuring pH value and content, and filtering after it is qualified, and loading and sealing.

Description

technical field [0001] The invention relates to an injection solution for treating hemorrhoids and a preparation method thereof. Background technique [0002] There are many types of injection solutions for treating hemorrhoids, among which the quick-acting necrotic tissue exfoliation agent with sodium sulfide as the main agent has a remarkable clinical effect. In order to avoid causing local pain to the patient during use, anesthesia ether is used as a local anesthetic in this medicine. Due to the use of anesthesia ether in the Chinese Pharmacopoeia, it is an inhalational general anesthetic. Therefore, in the infusion liquid that is used for the treatment of hemorrhoid fistula, the anesthesia effect is very unsatisfactory. In the preparation process of the above-mentioned infusion solution, another effect of anesthesia ether is to dissolve menthol, but in fact it does not completely dissolve but floats on the surface of the liquid. in an ampoule. In...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/04A61P9/14
Inventor 冯国庆勾大卉陆伟民万仲强
Owner 葫芦岛国帝药业有限责任公司
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