Babu agent matrix and its preparing method

A technology of cataplasm and matrix, which is applied in the field of cataplasm bases for making cataplasms and various medical external patches, and can solve the problems of inconspicuous drug release ability, poor moisture retention, and poor air permeability.

Inactive Publication Date: 2004-02-04
天津宝方生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, many cataplasm bases currently have shortcomings such as weak adhesion, poor moisture retention, poor air permeability, and inconspicuous ability to release drugs. Catalyst matrix as the basic raw material for poultice production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0011] Divide 37.2 grams of glycerin into three equal parts for later use. Crush 3.5 grams of carbo resin, 6.6 grams of apricot or plum gum or maple gum or peach gum, and 6.2 grams of gelatin for later use. Add 3.5 grams of carbo resin to one portion of glycerin , and fully stirred and mixed at 50°C to 70°C for 1 hour, completely dissolved to obtain a viscous solution (A) of carbomer resin; then take another part of glycerin and mix 6.6 grams of apricot gum or plum gum or maple gum or peach gum, Add 6.2 grams of gelatin, 26 grams of distilled water, and 1.4 grams of sodium hydroxide, and mix thoroughly for 1 hour at a temperature of 50°C to 70°C. After completely dissolving, a gelatin mixed viscous solution (B) is obtained; 2.8 grams of borneol, 1.8 grams of camphor Add 0.02 gram of allosteric cutinase into 3.6 grams of medical 95% ethanol, dissolve completely and mix with the third part of glycerin to obtain borneol, camphor, cutinase mixed solution (C); solution (A) and (B) a...

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Abstract

A matrix used for preparing the Babu preparation and various exterior-applied medical pickings are disclosed. Its advantages are high capacity of included medicine, high percutaneous effect and air permeability, controlled slow release and no irritation to skin.

Description

technical field [0001] The invention relates to a cataplasm base and a preparation method of the cataplasm base, more specifically the invention relates to a cataplasm base used for making cataplasms and various external medical patches. Background technique [0002] The cataplasm matrix is ​​mainly used to make cataplasms, and can also be directly used in various medical external patches. The concept of cataplasms originated in Europe and Japan in the 1960s and 1970s. At that time, the medical circles in Europe and Japan were all committed to improving traditional external patches, and tried to study a kind of patch with large drug tolerance, good transdermal effect, It is an ideal topical drug delivery platform (transdermal patch delivery system) with five characteristics of controllable drug dosage and sustained release, good air permeability, and no irritation to the skin. For this purpose, they call the product of this concept a cataplasm. However, many cataplasm bases...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K9/70A61K47/42
Inventor 马延辉王宁温宁哲
Owner 天津宝方生物医药有限公司
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