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Oral Prepn.

A technology of attapulgite and attapulgite, applied in drug delivery, active ingredients of aluminum/calcium/magnesium, digestive system, etc., can solve the problems of no attapulgite, high production cost, complicated technical route, etc., and achieve low product cost , lower product cost and simple process

Inactive Publication Date: 2004-07-21
NANJING UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Attapulgite has been used for wound healing treatment, but there is no oral preparation of attapulgite
[0003] Although there are similar oral preparations on the foreign market, their production costs are relatively high and the technical route is complicated

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0014] Various oral dosage forms were processed in the research. One of the main technical indicators is to hope that the preparation can disintegrate quickly, have a good dissolution rate, and can quickly disperse in the body to achieve the purposes of adsorption, mucosal protection, sterilization and anti-inflammation.

[0015] The processed dosage forms mainly include:

[0016] Attapulgite granules, attapulgite powder, attapulgite tablets, attapulgite capsules, attapulgite chewable tablets, attapulgite dispersible tablets, attapulgite solution, attapulgite gel.

[0017] Production process of attapulgite powder:

[0018] Take 10 kg of attapulgite, dry at 80°C for 1-4 hours, cool, sieve, activate at 200°C, add 1-2% magnesium stearate, 3% sugar, a small amount of essence, and pack separately to get the finished product 10.5 Kilogram.

[0019] Main excipients included in the preparation process:

[0020] In addition to the effective active ingredient attapulgite, the prescri...

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PUM

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Abstract

An orally applied medicine for treating acute or chronic diarrhea is prepared from attapulgite and auxiliary through proportionally mixing. Its advantages are high curative effect, quickly taking its effect, and no by-effect and recurrence.

Description

1. Technical field [0001] The invention belongs to the technical field of pharmaceutical preparation technology and changing medication route. 2. Background technology: [0002] The active ingredient of the invention is natural attapulgite powder in my country, which is a safe natural ore powder produced in China and has strong adsorption. Currently, attapulgite has been used for wound healing, but there is no oral preparation of attapulgite. [0003] Although there are similar oral preparations on foreign markets, their production costs are relatively high and their technical routes are complicated. 3. Contents of the invention: [0004] The purpose of the present invention is to develop the attapulgite resources with abundant reserves in my country into a series of preparations that can be taken orally for the treatment of various gastrointestinal diseases. Including: attapulgite granules, attapulgite powder, attapulgite tablets, attapulgite capsules, attapulgite chewa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61K33/12A61P1/12
Inventor 胡一桥赵恂
Owner NANJING UNIV
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