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Tissue blood-oxygen parameter detection method capable of amending outer layer tissue influence

A parameter detection and organization technology, applied in the field of biomedical engineering, can solve problems such as complex system structure, weak signal, and reduced sensitivity, and achieve the effects of improving detection accuracy, reducing influence, and increasing strength

Inactive Publication Date: 2004-11-03
TSINGHUA UNIV
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Problems solved by technology

This approach makes the system complex and reduces the sensitivity of weak signals

Method used

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  • Tissue blood-oxygen parameter detection method capable of amending outer layer tissue influence
  • Tissue blood-oxygen parameter detection method capable of amending outer layer tissue influence
  • Tissue blood-oxygen parameter detection method capable of amending outer layer tissue influence

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Embodiment Construction

[0037] In order to minimize the impact of outer tissue on detection accuracy. The present invention firstly requires that the distance d from the light source on the sensor to the detector be properly determined according to the type and thickness of the outer tissue of the object to be measured. The thickness of the outer tissue can be obtained by conventional ultrasound techniques. When the outer tissue is thicker, the distance should take a larger value to ensure that the photons can penetrate into the tissue to be tested. According to experience and experimental results, d is 50mm when measuring adult brain oxygen, and 30mm when measuring infant brain d. When the muscle is measured and the fat thickness is greater than 15mm, d is 50mm, otherwise it is appropriate to take 40mm. multi-layer organizational structure such as figure 2 shown. exist figure 2 1 is the light source LS1 at a distance r1 from the optical sensor OPSU, 2 is the light source LS2 at a distance r2 f...

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Abstract

The blood oxygen parameter measuring method capable of correcting the influence of outer tissue belongs to the field of biomedicine engineering. The present invention features that for different measured targets and different biological tissues, proper detection distance is selected in detecting oxidized hemoglubin variation and reduced hemoglubin variation; sensor design, detection steps, algorithm and system design are proposed in considering the influence of outer tissue. The sensor consists of three LED's and one photoelectric detector; and the whole test system consists of sensor, pre-amplifier, A / D converter, embedded micro controller, communication circuit, power supply, LCD and touch screen. The present invention has the advantages of high detectioin sensitivity and simple detection system structure.

Description

Technical field: [0001] A tissue blood oxygen parameter detection method capable of correcting the influence of outer tissue belongs to the field of biomedical engineering. Background technique: [0002] Using near-infrared dual-wavelength spectroscopy to detect changes in oxygenated (and reduced) hemoglobin in biological tissues is a mature technology at home and abroad. However, due to the influence of outer tissue (outer tissue refers to the tissue covered outside the tissue to be tested, such as the coverage of fat on muscle, the coverage of scalp, skull and cerebrospinal fluid on the cerebral cortex), it greatly affects the detection accuracy. precision. To this problem, do not have the literature of relevant patent abroad, the domestic disclosed three related patents (its publication number is respectively CN1333001A, CN1331953A, CN1365649A) all adopt a plurality of photosensitive dimmers arranged on a straight line with unequal distances from the light source. The m...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/145A61B6/00
Inventor 黄岚王广志丁海曙田丰华赵军
Owner TSINGHUA UNIV
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