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Stauntonvine general glycoside and injection

A technology of total glycoside injection and wild papaya, applied in the directions of anti-inflammatory agents, non-central analgesics, organic active ingredients, etc., can solve the problems of incomplete extraction of active ingredients, unstable quality and curative effect, and large side effects.

Inactive Publication Date: 2005-01-12
广州安健实业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The currently marketed injection for clinical use is Wild Papaya Injection, which is made from raw medicinal materials by traditional methods of water extraction and alcohol precipitation. The extraction of active ingredients is incomplete and the content of impurities is high.
The quality of raw materials in different production areas and different picking seasons is quite different, which makes the quality and curative effect of wild papaya injection between batches not stable enough
And side effects are large, there is a certain safety hazard

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0018] Preparation method of papaya total glycosides raw material

[0019] 1. Soak wild papaya in 75% ethanol with 20 times the volume of wild papaya for 12 hours, then reflux extraction 4 times, combine the extracts, and reclaim ethanol by distillation under reduced pressure to obtain a dilute alcohol extract. Then take 1 part of the dilute alcohol extract, dissolve it in 3 parts of water, then extract 5 times with 3 parts of water-saturated n-butanol, combine the extracts, recover n-butanol under reduced pressure, dry the obtained solid, and pulverize it to obtain wild The effective part of papaya is the total glycosides of papaya.

[0020] 2, the preparation method of papaya total glycosides injection

[0021] The preparation of papaya total glucoside raw material is the same as embodiment 1.

[0022] Prescription 1:

[0023] Total Papaya Glucosides 200g

[0024] Tween 20 1g

[0025] Add water for injection to 2000ml

[0026] A total of 1,000 tubes wer...

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Abstract

A papaside and its injection is prepared from wild papaya through extracting in alcohol to obtain the papaside, and preparing its injection or the injection of its water-soluble salt.

Description

technical field [0001] The invention relates to an injection composed of total glycosides of papaya, an effective part of the plant Akebia chinensis, or a water-soluble salt thereof. Background technique [0002] Wild papaya (Stauntonia chinensis DC), also known as false litchi and winding rattan, is a plant of the genus Papaya in the family Akebia. Pharmacological experiments have proved that the whole plant of wild papaya and its extracts have analgesic, sedative and antispasmodic effects, and are used to treat rheumatoid arthritis, bruises, and various neuropathic pains. It can be used for a long time and continuously, and the dose is positively correlated with the effect. The analgesic effect does not affect people's consciousness and feeling. It has no drug resistance and no addiction. It is an effective traditional Chinese medicine analgesic. The currently marketed injection for clinical use is Wild Papaya Injection, which is made from raw medicinal materials by tradi...

Claims

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Application Information

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IPC IPC(8): A61K31/7028A61P19/02A61P29/00
Inventor 傅卫国王伟曾韶辉
Owner 广州安健实业发展有限公司