Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Use of Chinese medicinal Bamatin in treatment of diabetes II

A technology for palmatine hydrochloride and diabetes, which is applied to palmatine hydrochloride, palmatine hydrochloride components, and application fields in the treatment of type II diabetes, and can solve the problems of hypoglycemia and excessive dosage of sulfonylurea drugs.

Inactive Publication Date: 2005-02-23
XI AN JIAOTONG UNIV
View PDF0 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] An obvious side effect of sulfonylureas is hypoglycemia when the dose is too large

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0026] The following is a further detailed description about the specific implementation and therapeutic effects of the present invention given by the inventor in conjunction with preferred embodiments.

[0027] 1. Extraction of effective parts of Coptidis Rhizoma and Phellodendron Phellodendri

[0028] Coptidis Rhizoma or Phellodendron Phellodendri was heated and refluxed twice with 85% ethanol in an amount of 8 times, each time for 2 hours. Combine the extracts, recover ethanol, and concentrate the water to make it viscous. Add 1 / 2 of the amount of medicinal materials in water, stir, filter with multi-layer gauze, and add an appropriate amount of Ca(OH) to the filtrate 2 , stirred, let stand for 24h, and filtered. Concentrate the filtrate, let it cool, adjust pH 1 to pH 2 with hydrochloric acid, let it stand still, there is precipitation, filter, dry the precipitation to obtain Phellodendron Phellodendri or Coptidis Rhizoma extract.

[0029] 2. TLC Qualitative Analysis of C...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

An application of the palmatine hydrochloride extracted from coptis root or phellodendron bark for treating diabetes B is disclosed.

Description

technical field [0001] The invention relates to a composition derived from raw materials of traditional Chinese medicines, in particular to a composition of palmatine hydrochloride derived from extracts of raw materials of Coptidis Rhizoma and Phellodendron Phellodendri. The present invention also relates to the application of palmatine hydrochloride in the treatment of type II diabetes. Background technique [0002] Diabetes mellitus (DM) is a clinical syndrome caused by the interaction of genetic and environmental factors, and is one of the most common endocrine diseases. Absolute or relative insufficiency of insulin secretion and decreased sensitivity of target tissues to insulin lead to a series of metabolic disorders of sugar, protein, fat, water and electrolytes. Clinically, three excesses (polyphagia, polydipsia, polyuria), one deficiency (weight loss), and hyperglycemia symptoms appear. According to different etiologies, diabetes can be di...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/4745A61P3/10
Inventor 杨广德贺浪冲李西玲赵良
Owner XI AN JIAOTONG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com