Guaiamar dripping pill
A technology of guaiacol glycerin and dripping pills, which is applied in the fields of pill delivery, respiratory diseases, organic active ingredients, etc., and can solve the problem of inflexibility due to disease, individual conditions, hepatic first-pass effect, and increasing number of patients Economic burden and other issues, to avoid the first-pass effect of liver and intestines, improve bioavailability, and reduce economic burden
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[0035] Below in conjunction with two groups of specific embodiment tests, the preparation process and test results of the guaiacol glycerin ether dripping pills involved in the present invention are further described.
[0036] Example Test 1 Prescription experiment of guaiacol glycerin and different substrates
[0037] Experimental Design: In order to observe the influence of guaiacol glyceryl ether and different matrix prescriptions on the guaiacol glycerin dripping pills involved in the present invention, polyethylene glycol 2000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 8000 , polyethylene glycol 10000 , stearic acid, sodium stearate, glycerin gelatin, polyoxyl 40 stearate, shellac, polyoxyethylene monostearate, polyether, sodium carboxymethyl starch, sodium lauryl sulfate, etc. Any one of the pharmaceutical excipients is used as a base, and the guaiacol glycerin and the above bases are formulated in a ratio of 1:4, and according to the...
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