Film-shaped mucoadhesive administration form for administering cannabis active ingredients

A pharmaceutical and mucous membrane technology, applied in the field of cannabis preparations, can solve problems such as unpleasantness and achieve the effect of improving compliance

Inactive Publication Date: 2005-08-24
LTS LOHMANN THERAPIE-SYST AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, another disadvantage of using the above-mentioned dosage forms is that the prolonged residence in the mouth of eg tablets or capsules (filled with an oil solution) is considered by the patient to be very unpleasant in certain cases

Method used

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Embodiment Construction

[0019] According to a preferred embodiment, the administration dosage form of the present invention includes a polymer matrix used as an active agent reservoir and has mucosal viscosity. At least one layer or at least one surface of the dosage form has mucosal viscosity. The dosage form for administration may consist of a single layer, or may include multiple layers. In the case of a multilayer structure, at least one layer contains one or more active agents.

[0020] In the simplest case, the dosage form for administration consists of a mucoadhesive, preferably monolayer, polymer matrix containing one or more cannabis preparations. The one or more active agents may be present in the dosage form in a dissolved, dispersed or emulsified form.

[0021] The polymer matrix preferably contains one or more water-soluble and / or swellable polymers in an aqueous medium. By choosing these polymers, it is possible to influence the mucosal viscosity and release behavior.

[0022] The following...

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Abstract

A film-shaped, mucoadhesive administration form having a content of at least one active agent. The active agent is a cannabis agent.

Description

Technical field [0001] The present invention relates to a film-shaped mucosal administration dosage form that has a certain content of cannabis preparations and is suitable for the administration of cannabis preparations for therapeutic purposes. The present invention further relates to the application of the dosage form for the treatment of human or animal diseases. Background technique [0002] The ingredients in the cannabis plant (Cannabis sativa L.) have a variety of pharmacological effects, of which the effect of treating psychosis is the most widely known. In addition to this effect, the cannabis component also has antiemetic, antispasmodic, muscle relaxation, analgesic, sedative and appetite-increasing effects. The therapeutic application of cannabis components is severely restricted because of the effect of treating psychosis or mental pleasure and the potential dependence associated with it. [0003] It has been known for a long time that cannabis components are used be...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61K9/70A61K31/352A61K36/60A61K47/32A61K47/34A61K47/36A61K47/38A61K47/42A61P1/08A61P11/06A61P15/00A61P19/02A61P25/00A61P25/04A61P25/06A61P25/08A61P25/16A61P25/28A61P25/32A61P25/34A61P25/36A61P27/06
CPCA61K9/006A61K9/7007A61P1/08A61P11/06A61P15/00A61P19/02A61P25/00A61P25/04A61P25/06A61P25/08A61P25/16A61P25/28A61P25/32A61P25/34A61P25/36A61P27/06A61P29/02
Inventor 沃纳·韦斯林
Owner LTS LOHMANN THERAPIE-SYST AG
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