486 results about "Cannabis ruderalis" patented technology

The disclosure relates to decarboxylated cannabis resins and methods of making the decarboxylated cannabis resins by extraction and decarboxylation of cannabinoids from Cannabis species using microwaves and solvents. The disclosure also relates to use of the decarboxylated cannabis resins for making pharmaceutical products comprising same.

Provided are compositions and methods of forming a particulate material derived from a cannabis plant. The method includes introducing a component including at least one of: (i) a cannabinoid, and (ii) a terpene, to a polymer to produce a polymeric mixture. The component is dispersed in the polymeric mixture, which is then at least partially dehydrated to encapsulate the component within a polymeric material derived from the polymer. The polymeric material is water soluble. The dehydrated polymeric mixture is processed to form particulates comprising the component encapsulated within shells formed from the polymeric material.

Cannabidiol (CBD) is a cannabinoid designated chemically as 2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol. Its empirical formula is C₂₁H₃₀O₂ and its molecular weight is 314.46. CBD is a cannabinoid that naturally occurs in the Cannabis sativa L. plant. CBD is a white to pale yellow crystalline solid which is insoluble in water and soluble in organic solvents. The present invention encompasses the surprising recognition that certain CBD preparations which are prepared from a botanical origin are more effective in treating diseases or disorders than preparations of CBD which are synthetic or purified to the extent no other impurities in the form of other cannabinoids are present. Prior CBD compositions have been prepared such that no psychoactive components, e.g., tetrahydrocannabinol (THC), remain in the final CBD preparation. Surprisingly, the absence of such minor impurities reduces the efficacy of CBD treatment. Such CBD preparations are characterized by chemical components and/or funtional properties that distinguish them from prior CBD compositions. One or more components of the preparations described herein provide an unexpectedly synergistic effect when utilized in combination.

The present invention relates to the use of cannabidiol (CBD) in the treatment of Angelman syndrome (AS). CBD has It been shown to be particularly effective in improving anxiety in rodent models of AS. The CBD is preferably substantially pure. It may take the form of a highly purified extract of Cannabis such that the CBD is present at greater than 98% of the total extract (w/w) and the other components of the extract are characterised. Alternatively, the CBD is synthetically produced. Alternatively, the CBD may be used as a botanical drug substance (BDS) from a Cannabis plant in which CBD is the predominant cannabinoid. The CBD may also be present in combination with other cannabinoids and non-cannabinoid components such as terpenes. In use the CBD may be used concomitantly with one or more other medicaments. Alternatively, the CBD may be formulated for administration separately, sequentially or simultaneously with one or more medicaments or the combination may be provided in a single dosage form. Where the CBD is formulated for administration separately, sequentially or simultaneously it may be provided as a kit or together with instructions to administer the one or more components in the manner indicated. It may also be used as the sole medication, i.e. as a monotherapy.

The invention discloses hemp leaf soothing and repairing essence, and belongs to the field of cosmetics. The product comprises the following components: a penetration enhancer, a whitening agent, a soothing agent, an allergy-relieving repairing agent and a skin conditioner, wherein the allergy-relieving repairing agent comprises a hemp leaf extract, carboxymethyl chitosan, a chia seed fermentationrepairing factor and an oat kernel extract. Carboxymethyl chitosan, the hemp leaf extract, the chia seed fermentation repair factor and the oat kernel extract are used as the allergy-relieving repairagent, so that the allergy-relieving repair agent has a synergistic effect and can achieve an instant and long-acting skin allergy-relieving/soothing effect in cooperation with the soothing agent inthe formula; in addition, through mutual cooperation with the skin conditioner, the penetration enhancer and the whitening agent, the cannabis sativa leaf soothing and repairing essence has excellentskin repairing performance, acne removing performance and whitening performance at the same time. The invention also discloses a preparation method of the cannabis sativa leaf soothing and repairing essence, and the method is simple to operate and can be industrially produced on a large scale.

The invention discloses a method for extracting and purifying cannabidiol in cannabis sativa, belonging to the field of chemical extraction and purification. The method comprises the following steps:harvesting, drying and crushing cannabis sativa leaves to obtain a clean material for later use; carrying out continuous countercurrent extraction on the clean material by adopting an ethanol solutionto obtain a crude extract; concentrating the crude extract, and conducting winterizing to remove impurities so as to obtain a winterized mixed solution; filtering the winterized mixed solution, heating the solution to 130-150 DEG C, and decarboxylating the solution for 1-2 hours to obtain a decarboxylated solution; carrying out column chromatography on the decarboxylation solution by using an ethanol solution to realize impurity removal, and conducting eluting by using the ethanol solution to obtain an eluent; concentrating the eluent to obtain an extract; supersaturating and dissolving the extract with a solvent, and then carrying out cooling to -30 DEG C to -10 DEG C to obtain a crystal substance; and washing the crystal substance with solvent, draining the crystal substance and then carrying out drying to obtain cannabidiol. According to the method, a decarboxylation degree is complete, the purity of cannabidiol is high, and tetrahydrocannabinol (THC) is almost not contained.

The invention discloses a preparation method of fructus cannabis protein powder containing water-soluble cannabidiol (CBD). The fructus cannabis protein powder containing the water-soluble cannabidiolis prepared by adding the water-soluble cannabidiol according to a certain ratio into the fructus cannabis protein powder, and has good health-care effects of improving sleep, resisting ageing, relaxing bowels, improving the immunity of the organism and the like. The water solubility of the CBD is improved through a special process on the premise of not changing the molecular structure of the CBD; protein and carbohydrate are rich in content in fructus cannabis except for fructus cannabis oil and are wonderful dietary protein sources. In the fructus cannabis protein powder, fat in the fructuscannabis is removed by a two-step method of fructus cannabis mechanical squeezing and supercritical CO2 extraction, defatted cakes are subjected to ultra-fine pulverization to obtain the fructus cannabis protein powder, nutrition is rich and loss is avoided; furthermore, the supercritical CO2 extraction efficiency is high, the fat is removed completely, solvent residues are avoided, environmentalfriendliness, healthiness and safety are realized, and high-quality fructus cannabis protein powder can be obtained.

The invention provides a microneedle patch for scar treatment and a preparation method thereof, the microneedle patch comprises a substrate and a needle body arranged on the surface of the substrate, the needle body comprises an anti-scar active component and a matrix material, the anti-scar active component comprises onion extract, cannabis sativa leaf extract, allantoin and heparin sodium in a mass ratio of 1: (0-1): (0-0.5): (0-0.02); the anti-scar active component mainly comprises an onion extract, the substrate also comprises a matrix material, and the matrix material comprises but not limited to hyaluronic acid, sodium hyaluronate, polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, sodium carboxymethyl cellulose, hydroxypropyl-beta-cyclodextrin, sodium alginate, polylactic acid, chitosan and glucan; the microneedle patch for scar treatment has certain mechanical strength, is convenient to use and good in stability, can realize minimally invasive painless effect when acting on skin, and provides a new and effective method for treatment of hypertrophic scars at any part of a body.

The present invention discloses a method for extracting and purifying cannabidivarol from industrial cannabis sativa. The method comprises the following steps: step one, crushing raw materials; step two, conducting baking; step three, conducting extraction: adding an extracting agent in flower and leaf powder after baking in the step two for extraction, recovering the extracting agent, and evaporating and concentrating a flowing-out extraction liquid to obtain a crude extract; step four, conducting dewaxing: dissolving the crude extract with ethanol, and conducting freezing, filtering and collecting to obtain a filtrate of a CBDV enrichment; step five, conducting molecular distillation: conducting desolventization and molecular distillation on the CBDV enrichment to obtain CBDV fat oil; step six, conducting resin column chromatography separation: firstly dissolving the CBDV fat oil with ethanol at a mass concentration of 50-60% and then loading samples to a resin column for chromatographic separation by a wet method to obtain a CBDV crude product; step seven, recovering an eluent; and step eight, recrystallizing the CBDV: dissolving the CBDV crude product with ethanol, conducting filtering, concentrating under reduced pressure, recrystallizing, and then filtering to obtain CBDV crystals. The method has advantages of simple process, environmental protection, low cost and high efficiency, and the purity of the prepared product is 99% or more.

Systems and methods for treating and packaging cannabis and cannabis-like materials, including systems and methods for sanitizing raw cannabis, and systems and methods for packaging cannabis products in receptacles for sale to and/or use by end users of the products. The systems include treatment systems for treating cannabis by utilizing a rotating conveyor and exposing cannabis on the conveyor to ultraviolet radiation. The systems further include packaging systems for filling receptacles with cannabis utilizing a feed funnel that has a tapering interior that slopes toward a funnel exit port, and an auger or a feed tool at the funnel exit port and extending into the receptacle to deliver a desired dose of the cannabis from the feed funnel.

A combination of THC, CBD and Cobalamin (in a ratio of about 63%, 27% and 10%, respectively) is used with a topical carrier such as Shea butter cream to relieve pain. The THC and CBD mixture is extracted from a Cannabis Indica dominant strain using high pressure and carbon dioxide (CO₂) as a solvent and comprises: Tetrahydrocannabinol “THC” (9-Tetrahydrocannabinol (delta-9 THC), 8-Tetrahydrocannabinol (Delta-8 THC) and 9-THC Acid), Cannabidiol “CBD”, Cannabinol “CBN”, Cannabichromene (“CBC”), Cannabigerol (“CBG”), terpenoids and flavonoids. The Shea butter is an extract from the Shea nut from the Shea tree (Vitellaria paradoxa).

Cannabis products and industrial methods for production thereof. A homogeneous composition comprising cannabinoid-containing comminuted cannabis plant material, where at least 70 weight % of the comminuted cannabis plant material is of a size greater than 0.3 millimeter and less than 4.2 millimeters; the composition comprises at least 1% by weight moisture and less than 20% by weight moisture; and the cannabinoid concentration in a 1 gram fraction of at least 10 gram sample of said homogeneous composition, is within 15% of the cannabinoid concentration in a separate 1 gram fraction of said 10 gram sample.

The invention discloses a method for separating cannabidiol by using a continuous chromatographic system. The method comprises the following steps: extracting a raw material cannabis flowers and leaves with ethanol, then performing concentrating to obtain an extract, dissolving the extract rich in cannabidiol by using a mobile phase to make the concentration reach 10-600 mg/mL, feeding the obtained raw material solution and the mobile phase into the continuous chromatographic system through a raw material pump and an elution pump, continuously collecting a cannabidiol solution from the raffinate port of the continuous chromatographic system, continuously collecting a tetrahydrocannabinol solution from an extraction port, concentrating and crystallizing the obtained cannabidiol solution toobtain a dry cannabidiol powder with the purity of 99.0% or above, and destroying the dry cannabidiol powder after the tetrahydrocannabidiol is concentrated, wherein a filler used by the continuous chromatographic system is a polymer filler. The purification method has the advantages of high yield, simple process, low solution consumption, high filler utilization rate, and suitableness for industrial production.

The present disclosure provides a new and distinct hemp cultivar designated ‘KIRSCHE’. The present disclosure relates to seeds of the hemp plant ‘KIRSCHE,’ to plants and parts of the hemp plant ‘KIRSCHE,’ and to methods for producing a hemp plant by crossing the hemp plant ‘KIRSCHE’ with itself or other Cannabis plants. The disclosure further relates to the morphological and physiological characteristics of the new and distinct hemp cultivar and its uses.

The invention provides a paddy environmentally-friendly pesticide which is prepared from a botanical insecticide and a special auxiliary agent, wherein the botanical insecticide is prepared from marijuana, serrate chloranthus root, Artemisia annua, tobacco, radix phytolaccae and field thistle, and the formulation of the botanical insecticide is as follows: 25-35kg of marijuana, 10-25kg of serrate chloranthus root, 15-20kg of Artemisia annua, 25-35kg of tobacco, 18-30kg of radix phytolaccae and 7-15kg of field thistle; aconite can be added into the formulation of the paddy environmentally-friendly pesticide, and the addition of the aconite is 5-10kg; and the auxiliary agent is prepared from the following components: 6-10kg of emulsifying agent, 10-15kg of turpentine, 3-5kg of penetrating agent, 0.4-1.5kg of antiseptic agent and 22-28kg of ethanol. The pesticide provided by the invention is prepared by scientifically processing pure natural plants utilized as raw materials, not only is low in toxicity but also has no toxicity residue problem, can not perform secondary killing on birds which are natural enemies of injurious insects and can not cause damage to human, animals and zoology, thus being an efficient, targeted, environmentally-friendly, secondary-toxicity-free, no-residue, no-pollution, nuisanceless and novel pesticide capable of keeping ecological balance, and being an important guarantee for realizing ecological agriculture, green ecological agriculture and green enterprises.

The invention discloses application of a whole hemp extract in preparation of drugs for preventing and treating cardiovascular and cerebrovascular diseases. The whole hemp extract is prepared by evenly mixing 0.3-99.7 parts of an industrial hemp and fructus cannabis extract and 0.3-99.7 parts of an industrial hemp and cannabis sativa L extract. Experiments prove that the whole hemp extract has the effects of improving the activity of SOD, GSH-PX and other anti-free-radical enzymes, scavenging free radicals and protecting cardio and cerebral blood vessels and tissues and preventing and controlling occurrence and development of the cardiovascular and cerebrovascular diseases. The whole hemp extract can be used for preparing the drugs for preventing and treating the cardiovascular and cerebrovascular diseases, such as cerebral ischemia, myocardial ischemia, neuronal damage caused by hypoxia-reoxygenation, cerebral infarction (stroke), cerebral thrombosis, cerebral hemorrhage, a coronary heart disease and myocardial infarction and has the good application prospect in treatment or prevention of the cardiovascular and cerebrovascular diseases.