'Lianzhi' anti inflammation drop pill in use for clearing away heat and toxic material and preparation method

The technology of dripping pills and fire poison is applied to lotus root anti-inflammatory dripping pills used for clearing away heat and detoxification and the field of preparation thereof, which can solve the problems of being unfavorable for improving the ability of patients to seek medical treatment, bioavailability of first-pass effect of liver and intestines, unfavorable overall health level and the like. , to achieve the effect of benefiting labor protection and environmental protection, improving bioavailability, and drug safety

Inactive Publication Date: 2005-08-31
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due

Method used

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Examples

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Embodiment Construction

[0032] The preparation method of Lianzhi Xiaoyan Dropping Pills of the present invention will be further described with several groups of specific examples.

[0033] Group 1: Tests with a single matrix

[0034] 1. Raw materials: 150g of Andrographis paniculata dry extract (calculated as total andrographis paniculata lactones), 430g of mountain sesame dry extract, pulverized into dry powder, mixed evenly, to obtain the drug extract dry powder containing total andrographis paniculata lactone and mountain sesame active ingredients for future use

[0035] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;

[0036] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0037] 4. Prepare according to the proces...

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Abstract

A Chinese medicine in the form of dripping pill for treating cough, asthma, parotitis, acute tonsillitis, sore throat, etc is prepared from green chiretta and narrowleaf screwtree root.

Description

technical field [0001] The present invention relates to a pharmaceutical composition which has the functions of clearing heat and detoxifying, cooling blood and reducing swelling, and is used for the treatment of cough, asthma, mumps, milk moth, sore throat and sore throat caused by heat in the lung and stomach, fire and poison. The invention relates to an oral preparation of a pharmaceutical composition prepared from two kinds of traditional Chinese medicines such as Andrographis paniculata extractum and Sesameum dry extractum as raw materials. Background technique [0002] According to the ministerial drug standard WS 3 - Lianzhi Anti-inflammatory Tablets prepared by the preparation method given in B-3977-98 is a kind of heat-clearing and detoxifying tablet, which is used for cough, asthma, mumps, and milk moths caused by heat in the lungs and stomach and fire toxins. , Oral tablets for the treatment of sore throat and sore throat have been clinically verified and have de...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P11/04A61P11/06A61P11/14
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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