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Knotweed rhizome glycoside dropping pill, capsule, granules and tablet preparing method for treating cardiovascular and cerebrovascular diseases

A cardiovascular and cerebrovascular and polydatin technology, applied in the field of drugs for the treatment of cardiovascular and cerebrovascular diseases

Inactive Publication Date: 2006-03-08
蒙一纯
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] So far, there have been no reports of polydatin dripping pills, soft capsules, capsules, granules, and tablets using polydatin as an active ingredient for the treatment of cardiovascular and cerebrovascular diseases. We have prepared a fast-acting, highly effective oral polydatin Preparations to meet the needs of clinical applications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Polydatin dripping pills

[0024] Mix 100g of polydatin powder with 200g of polyethylene glycol 6000, heat to 85°C, and after 20 minutes, transfer it to the drip irrigation of the dripping pill machine and keep it at 75°C. The liquid medicine is dropped into the liquid paraffin of 8 ℃ with the speed of 65 grains per minute, takes out the dropping pills, removes the liquid paraffin, selects the pills, and makes 1000 dropping pills.

Embodiment 2

[0026] Polydatin Soft Capsules

[0027] Take 276g of polyethylene glycol 400, put it in a suitable container, add 6g of polyethylene glycol 6000, heat in a water bath until the polyethylene glycol 6000 dissolves, stir well, add 18g of glycerin, add 100g of polydatin powder, and stir well with a homogeneous mixer To uniform paste, transfer to the soft capsule machine storage barrel, press into soft capsules with a mold of 0.3ml, make 1000 soft capsules.

Embodiment 3

[0029] Polydatin Capsules

[0030] Mix 100g polydatin powder with 75g starch, moisten with 30% ethanol to make soft material, pass through a 100-mesh nylon sieve to granulate, dry at 70-80°C for 30 minutes, granulate with a 100-mesh iron sieve, add 5g of stearin Magnesium acid is mixed, and capsules are packed into 1000 capsules.

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PUM

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Abstract

The present invention relates to a medicine for curing angiocardiopathy and cerebrovascular diseases. Said medicine uses polydatin as effective component, can be made into various dosage forms of dripping pills, soft capsule granules and tablet, etc. Said invention also provides its preparation method.

Description

technical field [0001] The invention relates to a medicine for treating cardiovascular and cerebrovascular diseases with polydatin as an active ingredient. Polydatin oral preparation drop pill, soft capsule, capsule, granule, tablet and preparation method thereof. Background technique [0002] The invention utilizes macroporous adsorption resin technology to separate and purify polydatin. Take the raw material, extract with ethanol or water, concentrate the extract, add water to dissolve to obtain a supersaturated solution, filter, apply the filtrate to a macroporous adsorption resin, concentrate the separated liquid, recover ethanol, and obtain the final product polydatin. Experiments have proved that the application effect is outstanding in the following aspects: [0003] (1) Hypotensive effect. [0004] (2) The effect of strengthening the heart and dilating blood vessels. [0005] (3) Inhibit platelet aggregation and antithrombotic effect. [0006] (4) Improve microc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/70A61K9/16A61K9/20A61K9/48A61P7/02A61P9/12A61P9/10
Inventor 蒙一纯路萍卢兖伟白旋
Owner 蒙一纯
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