Formulations comprising an active ingredient and cocoa powder and use thereof
A technology for active pharmaceutical ingredients and preparations, applied in the field of preparations containing active ingredients and cocoa powder and their uses, capable of solving problems such as unsuitable for oral or oral preparations
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Embodiment 1
[0038] Cocoa powder can be used in non-alkalized form and alkalinized form. Both can be used in the formulation of the present invention. When a slightly milder taste is required, alkalized cocoa powder is preferred.
[0039] Melt part of the hydrogenated soybean oil. Add solid components, that is, API (if solid) (Eritriptan hydrobromide is solid), cocoa powder, mannitol, corn starch, aspartame, acesulfame-K, titanium dioxide, chlorinated Sodium and flavoring agent (if solid), mix. Grind in a roller refiner to reduce the particle size of the solid components. If the solid components have reached the required particle size, for example, they are ground before mixing with the lipid components, roll refining is omitted. After processing in a roller refiner, the mixture is mixed with the remaining melted lipid components or re-melted (if cured) and mixed with the remaining melted hydrogenated soybean oil. The mixing of the melt is carried out in a suitable mixer. Add the liquid ...
Embodiment 2
[0040] Example 2: Preparation of another embodiment
[0041] Ingredients
Embodiment 3
[0042] Example 3: Preparation of another embodiment
[0043] Ingredients
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