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Air-vapor coupling vapor exploding ephedrine wall breaking method

An extraction method and technology of ephedrine, applied in the field of air-steam coupled steam explosion wall-breaking extraction, can solve the problems of low utilization rate of raw materials, waste of ephedra resources, environmental pollution, etc., and achieve the goal of protecting traditional Chinese medicine components, improving utilization rate, and increasing extraction rate Effect

Inactive Publication Date: 2006-05-17
INST OF PROCESS ENG CHINESE ACAD OF SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The purpose of the invention is: in order to meet the needs of ephedrine industrial extraction and solve the extraction rate of traditional ephedrine extraction process is low, high energy consumption, low utilization rate of raw materials, resulting in waste of ephedra resources, environmental pollution and other problems, and provide a Extraction method of ephedrine from Ephedra herba by air-steam coupled steam explosion wall breaking

Method used

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  • Air-vapor coupling vapor exploding ephedrine wall breaking method
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  • Air-vapor coupling vapor exploding ephedrine wall breaking method

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Embodiment 1

[0020] Embodiment 1, extracting ephedrine step with the method of the present invention is as follows:

[0021] 1) Put the ephedra grass material roughly cut to a length of 20-30mm into the steam explosion tank, use air and water vapor as the steam explosion medium, and first feed air until the pressure in the steam explosion tank is 5kg / cm 2 , and then quickly inject steam until the pressure inside the steam explosion tank is 10kg / cm 2 , steam explosion treatment for 20 minutes, then immediately open the discharge ball valve, so that the ephedra material is sprayed into the normal pressure release tank;

[0022] 2) The ephedra grass material after the pretreatment of air-steam coupling steam explosion wall breaking is extracted by immersion in water for 3 times, the weight ratio of grass and water is = 1:8, the extraction temperature is 80°C, and the extraction time is 120min . The extraction rate of ephedrine of the present embodiment is 78.06%.

Embodiment 2

[0023] Embodiment 2, extract ephedrine step as follows with the method of the present invention:

[0024] 1) Put the ephedra grass material roughly cut to a length of 20-30mm into the steam explosion tank, use air and water vapor as the steam explosion medium, and first feed air until the pressure in the steam explosion tank is 8kg / cm 2 , and then quickly inject steam until the pressure inside the steam explosion tank is 12kg / cm 2 , steam explosion treatment for 2 minutes, then immediately open the discharge ball valve, so that the ephedra material is sprayed into the normal pressure release tank;

[0025] 2) The ephedra grass material after the pretreatment of air-steam coupled steam explosion wall breaking is extracted by 4 times of water immersion, the weight ratio of the grass and water is = 1:12, the extraction temperature is 100 ° C, and the extraction time is 30 minutes . The ephedrine extraction rate of the present embodiment is 80.56%.

Embodiment 3

[0026] Embodiment 3, extract ephedrine step as follows with the method of the present invention:

[0027] 1) Put the ephedra grass material roughly cut to a length of 20-30mm into the steam explosion tank, use air and water vapor as the steam explosion medium, and first feed air until the pressure in the steam explosion tank is 8kg / cm 2 , and then quickly inject steam until the pressure inside the steam explosion tank is 15kg / cm 2 , steam explosion treatment for 3 minutes, then immediately open the discharge ball valve, so that the ephedra material is sprayed into the normal pressure release tank;

[0028] 2) The ephedra grass material after the pretreatment of air-steam coupling steam explosion wall breaking is extracted by immersion in water three times, the weight ratio of grass and water is = 1:10, the extraction temperature is 100°C, and the extraction time is 120min . The extraction rate of ephedrine of the present embodiment is 91.3% (the extraction rate of once extra...

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Abstract

The air-vapor coupling vapor exploding ephedrine wall breaking process includes the following steps: 1. setting cut ephedra material inside vapor exploding tank with air and steam as vapor exploding medium, introducing air to pressure 5-10 kg / sq cm, fast introducing steam to pressure 10-18 kg / sq cm, steam exploding for 2-20 min, opening the discharge ball valve fast to spray the ephedra material into normal pressure releasing tank; and 2. 2-4 stage water soaking and boiling extraction of the steam exploding wall breaking treated ephedra material at 80-100 deg.c for 30-120 min to obtain ephedrine aqua in high lixiviating rate. The present invention has the advantages of mild steam explosion condition, no loss of the Chinese medicine components, high extracting rate, simple operation, low cost, less exhausted waste water with organic matter and high material utilization rate.

Description

technical field [0001] The invention belongs to the field of processing of traditional Chinese medicinal materials, and mainly relates to an extraction method for extracting ephedrine from ephedra herba with air-steam coupled steam explosion wall breaking. Background technique [0002] The source of ephedra (herba ephedrae) is the dry herbaceous stem of ephedra (Ephedra intermedia Schrenk et C.A.Mey.) or horsetail ephedra (Ephedra equisetina Bge.) in Ephedra sinica Stapf. A kind of traditional Chinese medicine in the world. As a Chinese herbal medicine, ephedra has high medicinal value. The whole herb of ephedra can be used as medicine, and it is an important raw material of traditional Chinese medicinal materials and pharmaceutical industry. There are at least 100 kinds of compounds that have been isolated and identified. Modern studies believe that its chemical composition contains more than 10 kinds of alkaloids, mainly 1-ephedrine (1-Ephedrine) and d-pseudoephedrine (d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01D11/02A61J3/00A61K36/17
Inventor 陈洪章原义涛
Owner INST OF PROCESS ENG CHINESE ACAD OF SCI
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