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Chinese medicinal composition for treating strangury patterns and preparation method of its oral liquid, tablet and capsule

The technology of a composition and an oral liquid is applied in the field of preparation of a traditional Chinese medicine composition for treating stranguria and its oral liquid, tablet and capsule, and can solve the problem that the solubility of granules is not very good, and the drug absorption and particle size are affected. Unqualified and other problems, to achieve the effect of solving the difficulty of taking granules, good drug absorption, and increasing stability

Inactive Publication Date: 2006-06-14
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This preparation is a granule, with 640g of dextrin and 40g of stevioside as auxiliary materials. It can be seen that the auxiliary materials account for more than 2 / 3 of the finished granules, which greatly increases the cost; and the prepared granules require higher hardness. , so as not to be crushed into fine powder, and when the hardness is high, the solubility of the granules is not very good, which affects the absorption of the drug; when the granules are loose, the particle size is often unqualified; the granules are taken It should be taken with boiled water before taking, which is inconvenient to take

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] [embodiment 1] preparation of oral liquid

[0026] Take each raw material by the following weight:

[0027] Four Seasons Red 2700g Plantain 1300g

[0028] Add water to decoct Sijihong and Plantain three times, each time for 1 hour, combine the decoction, filter, concentrate to a clear paste with a relative density of 1.10-1.15 (50°C), let it cool, add ethanol to make the alcohol content reach 50% , stir well, let it stand for 24 hours, take the supernatant to concentrate for later use, recover ethanol, add 3-5g of preservative sodium benzoate to the concentrated solution of the supernatant, add water to make it 5000ml, filter, fill, sterilize, Instantly.

Embodiment 2

[0029] [embodiment 2] preparation of oral liquid

[0030] Take each raw material by the following weight:

[0031] Four Seasons Red 540g Plantain 260g

[0032] Add water to decoct Sijihong and Plantain three times, each time for 1 hour, combine the decoction, filter, concentrate to a clear paste with a relative density of 1.10-1.15 (50°C), let it cool, add ethanol to make the alcohol content reach 50% , stir well, let it stand for 24 hours, take the supernatant to concentrate for later use, recover ethanol, add 3-5g of preservative sodium benzoate to the concentrated solution of the supernatant, add water to make it 1000ml, filter, fill, sterilize, Instantly.

Embodiment 3

[0033] [Example 3] Preparation of tablet

[0034] Take each raw material by the following weight:

[0035] Four Seasons Red 2700g Plantain 1300g

[0036] Add water to decoct Sijihong and plantain three times, each time for 1 hour, combine the decoction, filter, concentrate the filtrate to a clear paste with a relative density of 1.10-1.15 (50°C), let it cool, add ethanol to make the alcohol content reach 50 %, stir evenly, stand still for 24 hours, recover ethanol, take the supernatant and concentrate to a thick paste with a relative density of 1.35-1.40 (50°C), dry, pulverize, add suitable auxiliary materials, and make 1000 tablets.

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PUM

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Abstract

A Chinese medicine in the form of oral liquid, tablet or capsule for treating urination disturbance is prepared from 2 Chinese-medicinal materials: Sijihong and plantain herb. Its preparing process is also disclosed.

Description

technical field [0001] An oral liquid, tablet and capsule for treating stranguria syndrome and a preparation method thereof. Background technique [0002] The incidence of gonorrhea accounts for as much as 2% of the total number of human beings, second only to non-gonococcal urethritis, and is the second among all sexually transmitted diseases. The incidence rate is very high in some countries in Europe, America and Africa, and it is widely prevalent in the world. STDs were reintroduced into my country in the 1980s, among which gonorrhea ranked first. [0003] Gonorrhea is an acute and chronic inflammation of the genitourinary system caused by infection with Neisseria gonorrhoeae. According to the survey, it occupies the first place in the incidence of sexually transmitted diseases in my country. In traditional Chinese medicine, it is called stranguria syndrome, turbid urine, and turbid essence. Gonorrhea is divided into two types: acute gonorrhea and chronic gonorrhea. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/70A61K9/08A61K9/10A61K9/20A61K9/48A61P13/02A61P31/04
Inventor 付立家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
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