Detection method of injection formulation containing raw material herb red sage root or red sage

Abstract

The present invention is one kind of injection containing medicine material red sage, and each preparation unit contains salvianolic acid A 0.5-7.5 mg and salvianolic acid B 0.5-7.5 mg. The present invention also provides the quality control method for the injection, and the contents of salvianolic acid A and salvianolic acid B are controlled to ensure the safety and effectiveness of the injection. The detection method is advanced, accurate, simple and suitable for conventional analysis. The present invention is significant in controlling the quality of different kinds of injection containingred sage component.

Description

Detection method of Xiangdan injection or Danshen injection technical field The invention relates to an injection containing salvia miltiorrhiza as a raw material and a quality control method thereof, belonging to the field of traditional Chinese medicines. Background technique Both Xiangdan injection and Danshen injection are traditional Chinese medicine injections containing Danshen. The raw materials contain Danshen, which has the function of dilating blood vessels and increasing coronary blood flow. It is used to treat cardiovascular diseases such as angina pectoris and myocardial infarction. The application is very extensive. The active ingredients of Danshen include water-soluble ingredients and fat-soluble ingredients. The water-soluble ingredients are mainly salvianolic acids, such as salvianolic acids A, B, C, D, E, shikonic acid, rosmarinic acid, etc. In addition, there are Danshensu, protocatechualdehyde, protocatechuic acid and so on. The research results sho...

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Problems solved by technology

It is also reported that preparative thin-layer chromatography is used for separation. This method has a small amount of preparation at one time, and the components are affected by oxygen in the air on the thin plate, so they are not stable enough.

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