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Application of compound vitamins in preparing medicine for treating tuberculosis

A compound vitamin and vitamin technology, applied in the directions of antibacterial drugs, pharmaceutical formulations, heterocyclic compound active ingredients, etc., can solve problems such as no reports of compound vitamin B, and achieve the effects of reducing adverse reactions, improving treatment effects, and improving tuberculosis.

Inactive Publication Date: 2006-08-02
JILIN SIHUAN PHARM CO LTD
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0007] In the data retrieval, there is no report on the above-mentioned compound vitamin B in the treatment of tuberculosis

Method used

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Embodiment Construction

[0033] Vitamin B 1 , Vitamin B 6 , Vitamin B 12 According to the method in the patent document whose application number is CN200410081179.4, it is prepared into a freeze-dried powder preparation, specifically: 20 g of thiamine nitrate, 300 g of pyridoxine hydrochloride, and vitamin B 12 25mg, can be made into 10000ml liquid medicine, and finally made into 10000 freeze-dried powder injections. Take 50% of the prepared water for injection and add it to the preparation tank, add thiamine nitrate, pyridoxine hydrochloride, vitamin B 12, after stirring and dissolving, add water for injection to the prepared amount, adjust the pH value to 3.2, and pass the intermediate inspection. In the drying box, the temperature of the freeze-drying box is rapidly reduced to -40°C, and the liquid is cooled for 1 hour to completely freeze it; after the liquid is completely frozen, the pressure in the freeze-drying box is reduced to 5 Pa, and the condenser is cooled. Let it cool down to -65°C; ...

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Abstract

The present invention belongs to the field of medicine preparing technology, and is especially application of compound vitamin B in preparing medicine for treating tuberculosis. The compound vitamin B is vitamin B1, vitamin B6, vitamin B12 or their mixture, and pharmacological experiment proves the excellent tuberculosis treating effect of the compound vitamin B.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to the application of compound vitamin B in the preparation of medicines for treating tuberculosis. Background technique [0002] Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis infection. Mycobacterium tuberculosis may invade various organs of the human body, but mainly invades the lungs, which is called pulmonary tuberculosis. Tuberculosis, also known as tuberculosis and "white plague", is an ancient infectious disease, and tuberculosis has existed since human beings existed. In history, it was widely popular all over the world and was once the main killer against human beings, taking hundreds of millions of lives. In 1882, Kojo discovered that the pathogenic bacteria of tuberculosis was Mycobacterium tuberculosis, but it is still widely prevalent in the world because there is no effective treatment drug. Since the 1950s, effective...

Claims

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Application Information

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IPC IPC(8): A61K31/495A61K31/51A61K31/525A61K31/714A61P31/06
Inventor 郭智华
Owner JILIN SIHUAN PHARM CO LTD
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