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Chinese medicinal composition for treating diabetes mellitus II

A composition and diabetes technology, applied in drug combination, metabolic disease, pharmaceutical formula, etc., can solve problems such as uncontrollable curative effect, unstable quality, and unknown mechanism

Inactive Publication Date: 2006-11-01
刘红杰 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the traditional Chinese medicine compound has the disadvantages of unclear ingredients, unknown mechanism, unstable quality, and uncontrollable curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] [embodiment 1] tablet preparation of medicine of the present invention

[0041] Take Atractylodes atractylodes powder, degrease with gasoline, heat extraction and reflux with 70%-90% ethanol for 3 times, concentrate the extract to dryness, dissolve in methanol, carry out silica gel chromatography on methanol soluble matter, ethyl acetate: ethanol (9 : 1) was eluted to obtain 20 g of Atractylodes atractylodis total glycosides.

[0042] Take Scrophulariaceae powder, extract by percolation with methanol, or put it into a flask 4-5 times, attach a reflux condenser, soak in a water bath at 50°C for extraction, each time for 2 hours, combine the extracts, and recover under reduced pressure at 50°C Solvent, a light yellow powder. Take the obtained powder, dissolve it in methanol 2-5 times the weight of the powder, slowly add 7-10 times the amount of chloroform, and stir while adding, a large amount of white precipitate is precipitated, filtered, and the filtrate is recovered ...

Embodiment 2

[0045] [embodiment 2] the capsule preparation of medicine of the present invention

[0046] Take Atractylodes atractylodes powder, degrease with gasoline, heat extraction and reflux with 70%-90% ethanol for 3 times, concentrate the extract to dryness, dissolve in methanol, carry out silica gel chromatography on methanol soluble matter, ethyl acetate: ethanol (9 : 1) was eluted to obtain 20 g of Atractylodes atractylodis total glycosides.

[0047] Take Scrophulariaceae powder, extract by percolation with methanol, or put it into a flask 4-5 times, attach a reflux condenser, soak in a water bath at 50°C for extraction, each time for 2 hours, combine the extracts, and recover under reduced pressure at 50°C Solvent, a light yellow powder. Take the obtained powder, dissolve it in methanol 2-5 times the weight of the powder, slowly add 7-10 times the amount of chloroform, and stir while adding, a large amount of white precipitate is precipitated, filtered, and the filtrate is recov...

Embodiment 3

[0050] [Example 3] Preparation of granules of medicine of the present invention

[0051] Take Atractylodes atractylodes powder, degrease with gasoline, heat extraction and reflux with 70%-90% ethanol for 3 times, concentrate the extract to dryness, dissolve in methanol, carry out silica gel chromatography on methanol soluble matter, ethyl acetate: ethanol (9 : 1) was eluted to obtain 20 g of Atractylodes atractylodis total glycosides.

[0052] Take Scrophulariaceae powder, extract by percolation with methanol, or put it into a flask 4-5 times, attach a reflux condenser, soak in a water bath at 50°C for extraction, each time for 2 hours, combine the extracts, and recover under reduced pressure at 50°C Solvent, a light yellow powder. Take the obtained powder, dissolve it in methanol 2-5 times the weight of the powder, slowly add 7-10 times the amount of chloroform, and stir while adding, a large amount of white precipitate is precipitated, filtered, and the filtrate is recovere...

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PUM

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Abstract

A Chinese medicine for treating the insulin-independent diabetes by interior application is proportionally prepared from atractylodes rhizome and scrophularia root through extracting.

Description

【Technical field】 [0001] The invention relates to a traditional Chinese medicine composition for treating non-insulin-dependent (type 2) diabetes and a preparation method thereof, belonging to the field of traditional Chinese medicines. 【Background technique】 [0002] Non-insulin-dependent (type 2) diabetes accounts for about 90% of the total number of diabetic patients, and is a common and frequently-occurring disease that endangers human health. The age of onset is mostly after the age of 35, and the onset is slow and insidious. The islet cells secrete more or less insulin, or normal, and the secretion peak shifts later. Insulin receptor or post-receptor defects on insulin target cells play an important role in pathogenesis. [0003] Non-insulin-dependent (type 2) diabetes can be treated with western medicine or traditional Chinese medicine. Western medicine mainly uses oral hypoglycemic drugs such as sulfonylureas, biguanides, and glycosidase inhibitors. These drugs can...

Claims

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Application Information

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IPC IPC(8): A61K36/808A61K9/16A61K9/20A61K9/48A61K36/8945A61P3/10
Inventor 刘红杰郑涛
Owner 刘红杰
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