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Prepn. method for compound Chinese lobelia liquid prepn. for external use

A kind of liquid preparation, technology of Lobelia

Inactive Publication Date: 2006-11-15
TIANKANG PHARMA HENAN PROV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current products and their preparation technology are limited to injections and their preparation technology, and there are still certain limitations in clinical application for different patients, different diseases, and different diseased parts.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Example 1: Add water for injection to the fine filtrate to adjust the concentration to 0.05-0.1 mg / ml, adjust the osmotic pressure, adjust the pH value to 6.0-7.0, sterilize, and fill. Thus, compound lobelia eye drops are prepared. When using, just drop the eye drops into the eyes.

Embodiment 2

[0014] Example 2: Add water for injection to the fine filtrate to adjust the concentration to 0.1-0.2 mg / ml, adjust the osmotic pressure, adjust the pH value to 6.0-7.0, sterilize, and fill. Thus, the compound lobelia nasal drops was prepared. When using, only need to drip the nose drops into the nasal cavity.

Embodiment 3

[0015] Example 3: Preparation of lotions and liniments for different cavities: add water for injection to the fine filtrate to adjust its concentration, generally: high concentration for oral cavity or ear canal, about 0.3mg / ml; use For the anus and rectum, the concentration is about 0.2mg / ml; for the urethra or vagina, the concentration is about 0.1mg / ml. Adjust the osmotic pressure, adjust the pH value to 6.0-7.0, sterilize, and fill. Thereby, various compound lobelia lotions and liniments with different purposes are prepared. These lotions and liniments can also be used on the skin of people of different ages.

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PUM

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Abstract

A Chinese medicine in the form of exterior-applied liquid is prepared from radical lobelia, barbat skullcap and oldenlandia through proportional decocting, filtering, concentrating, adding alcohol, laying aside, filtering, regulating pH value, filtering, recovering alcohol, regulating pH value, adding activated carbon, boiling, filtering, regulating pH value, cold storage, filtering, regulating concentration, osmotic pressure and pH value, sterilizing, and pouring it in container.

Description

Technical field [0001] The invention belongs to the field of medical technology, and specifically relates to a preparation method of a compound lobelia powder preparation for external use. Background technique [0002] The use of compound lobelia injections prescribed as Lobelia, Scutellaria barbata, and Oldenlandia diffusa has been promulgated by the National Medical Products Administration WS-10609 (ZD-0609) 2002 "Standard (Trial)" (hereinafter referred to as "Standard" 》) Announcement and implementation. The injection has played a great role in clearing away heat and detoxification, reducing swelling and pain, especially as an adjuvant drug in chemotherapy for cancer patients. However, the current products and their preparation technologies are limited to injections and their preparation technologies. In clinical applications, there are still certain limitations for different patients, different diseases, and different diseased parts. [0003] Purpose of invention [0004] The...

Claims

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Application Information

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IPC IPC(8): A61K36/76A61K9/08A61K36/34A61K36/53A61P29/00A61P35/00
Inventor 于涛王立清
Owner TIANKANG PHARMA HENAN PROV