Application of salvianolic acid B in preparing medication for preventing tumorigenesis
A salvianolic acid and drug technology, applied in the field of medicine, can solve the problems of tissue cell damage, inability to prevent tumors, inability to take long-term medication, etc.
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Embodiment 1
[0058] Experimental observation on the preventive effect of salvianolic acid B and its magnesium salt on rat prostate cancer
[0059] 1. Experimental materials
[0060] (1) Experimental animals: F344 male rats, 5 weeks old, weighing about 90 grams;
[0061] (2) Prostate cancer chemical inducer: 3,2'-dimethyl-4-aminobiphenyl (DMAB) (purchased from Nard Research Institute, Japan);
[0062] (3) Experimental drug: salvianolic acid B, magnesium salt of salvianolic acid B;
[0063] 2. Experimental grouping: The experimental animals are divided into 10 groups.
[0064] (1) Blank control group (normal diet, no DMAB chemical induction): 1 group, 6 animals / group;
[0065] (2) Salvianolic acid B control group (salvianolic acid B mixed feed, without DMAB chemical induction): 1 group (200mg / kg / day dose group), 6 animals / group;
[0066] (3) Salvianolic acid B magnesium salt control group (salvianolic acid B magnesium salt mixed feed, no DMAB chemical induction): 1 group (200mg / kg / day dose group...
Embodiment 2
[0096] Experimental observation on the preventive effect of salvianolic acid B and its magnesium salt on liver cancer in rats
[0097] 1. Experimental materials
[0098] (1) Experimental animals: Wistar male rats, weighing about 90g;
[0099] (2) Chemical inducer of liver cancer: diethylnitrosamine (DENA);
[0100] (3) Experimental drugs: salvianolic acid B, magnesium salt of salvianolic acid B;
[0101] 2. Experimental grouping: The experimental animals are divided into 10 groups.
[0102] (1) Blank control group (normal diet, no DENA chemical induction): 1 group, 6 animals / group;
[0103] (2) Salvianolic acid B control group (salvianolic acid B mixed feed, no DENA chemical induction): 1 group (200mg / kg / day dose group), 6 animals / group;
[0104] (3) Salvianolic acid B magnesium salt control group (salvianolic acid B magnesium salt mixed feed, no DENA chemical induction): 1 group (200mg / kg / day dose group), 6 animals / group;
[0105] (4) DENA model control group (normal diet, with D...
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