1H-imidazo[4,5-C]quinoline derivatives in the treatment of protein kinase dependent diseases
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- NOVARTIS AG
- Publication Date
- 2006-12-20
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
[0001] The present invention relates to the use of imidazoquinoline compounds and salts thereof in the treatment of protein kinase-dependent diseases and in the preparation of pharmaceutical preparations for treating the diseases; imidazoquinoline compounds for the treatment of protein kinase-dependent diseases; Method for treating said diseases, comprising administering imidazoquinolines to warm-blooded animals, especially humans; pharmaceutical preparations comprising imidazoquinolines, especially for the treatment of protein kinase-dependent diseases; novel imidazole and quinolines; and methods of preparing novel imidazoquinolines. Background technique
[0002] Recently, the concept of treating proliferative diseases with drugs specifically designed to act against abnormally active protein kinases has been well established in the treatment of chronic myelogenous leukemia (CML), with the first product now approved for Successful treatment. Clinical studies have shown that t...