Sinusoidal tensile cell loader

Abstract

A kind of sine pulls to stretch cell to add to carry device, involve a medical science experiment instrument in of the cell mechanics add to carry device. The invention mainly includes a machine, wheel gear deceleration to adjust soon electrical engineering, number to show to adjust soon a machine, crank a slippery piece organization and pulls to stretch sport organization. The crank slips a piece of organization mainly from adjust a pole, the song arm slippery piece, crank and pull pole composing; Pull to stretch sport organization mainly from glide a support, fix support, direction pole, pioneer pole piece and behind lead a pole piece composing. Because the invention has structure simple, operate simple, maintenance convenience, the cost is cheap, circulating steady, sex price ratio high, the cell is subjected to dint even, can regulate to pull to stretch characteristics, such as range and frequency...etc., pull to stretch distance can the convenience regulates within the scope of 0~25 mm, can satisfy various cell which stick a wall growth to carry on the mechanics incitement which pulls to stretch to add to carry to respond to a research, so the invention can used to the cell mechanics within instrument of the medical science experiment to add to carry device extensively, being applicable to funds and profession to operate the think factory that the personnel lacks specially extensively applied.

Description

technical field [0001] The invention belongs to the technical field of biomechanical engineering, in particular to a sinusoidal loading device for cell mechanics in medical experiment instruments. technical background [0002] With the development of tissue engineering and biomedical engineering, cell mechanics and tissue engineering have become frontier subjects in the development of modern biology. In order to study the effects of various physical and biochemical factors on human tissues, it is necessary to solve the problem of how to mechanically load cells. In the existing cell loading device, such as the patent of "Four-Point Bending Cell Mechanics Loading Apparatus" with publication number CN1425905A, it is disclosed that the stepper motor executes the commands of the CPU, thereby driving the punching head to run various speeds, displacements, stamping The head deforms the beam between the four support points of left and right symmetry, so that the surface area of ​​t...

AI Technical Summary

Problems solved by technology

The advantage of this loading instrument is that the control operation is completed by the CPU, and the cells are stretched or compressed in different forms through a stepping motor. However, the main problems of this loading instrument are: 1. The beam is between the four supporting points The deformation of the cell is uneven, which will inevitably lead to uneven deformation of the adherent growth cells on the culture plate

2. The deformation between the four support points is determined by the displacement of the stamping head and converted through the middle of the beam, which makes the cell deformation unintuitive and will cause errors

3. The loading instrument cannot achieve microscopic observation of cells under tension or compression

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