Affinity particle and affinity separation method

A separation method and affinity technology, applied in the field of affinity separation, can solve the problems that organic particles are prone to agglomeration, require more time for purification, and have low capture efficiency, and achieve prevention of non-specific adsorption, excellent dispersibility, and low purification efficiency. Effect
CN1956780AInactive Publication Date: 2007-05-02SHISEIDO CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHISEIDO CO LTD
Publication Date
2007-05-02
Estimated Expiration
Not applicable · inactive patent

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Abstract

The object of the present invention is to provide affinity particles, which are characterized in that: the surface of the organic particles has a phosphorylcholine group represented by the following formula (1) in the form of covalent bonding or adsorption. A ligand with specific affinity for a target substance. Another object of the present invention is to provide an affinity separation method that can easily and accurately separate a target substance by using affinity particles of organic particles.
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Description

technical field

[0001] The present invention relates to affinity particles and affinity separation methods. More specifically, it relates to affinity particles using organic particles and an affinity separation method capable of separating target substances with high precision and easily. The affinity particles of the present invention are also extremely useful for various separation, purification, and detection methods represented by immunoprecipitation, latex agglutination, and the like, which can detect target substances with high precision and easily. Background technique

[0002] Conventionally, separation and purification of biological substances have been performed by column chromatography. However, there are fatal problems shown in the following (1)-(3) in column separation.

[0003] (1) In order to obtain the target substance, various columns must be used, and the purification efficiency is poor.

[0004] (2) Confirmation experiments must be carried out to confir...

Claims

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