24 results about "Biological substances" patented technology

An aseptic containment chamber defines a containment volume for the handling and / or processing of chemical-pharmaceutical-biological substances and comprises a lighting system with adjustable colour temperature; the lighting system comprises a lighting body having at least one LED source configured to emit at least one beam of warm light and / or a beam of cool light of adjustable intensity and directed towards the inside of the containment volume and at least one unit for the adjustment and / or partialisation of the current in relation to the voltage and / or intensity for adjusting the emission of the beam of warm and / or cool light from the LED source.

Provided herein is a biological substance treatment method in which a flow cell is prepared, the flow cell including a chamber array device including a plurality of chambers and a cover body defining a flow path communicating with an opening of the plurality of chambers and provided in common for the plurality of chambers.

The capsule module for multi-collection of intestinal biological substances according to the present invention can collect intestinal samples in various places within the gastrointestinal tract by means of the administration of a single capsule without the aid of an external system and thus can improve the accessibility and convenience of intestinal microorganism research.

A compound having two or more phosphor parts having mutually equivalent light absorption characteristics, wherein adjacent phosphor parts are connected via a group including a structure represented by general formula (I), and a labeled biological substance using the compound. In the formula, X1 to X3 represent-O-,-S-, > NR1, or > CR2R3. And each of R1-R3 and R11 represents a hydrogen atom or a substituent. And R8 represents a hydrogen atom or a substituent. And n is an integer of 2 or more. And * represents a connecting bond.

A compound containing two or more phosphor moieties, in which each of the phosphor moieties adjacent to each other is linked by a linking group having a Molecular Flexibility of 0.510 or less and a cLogP of 6.0 or less, and a labeled biological substance using the compound.

The invention discloses a preparation method of a material for enriching hydrophilic biological substances, which is characterized in that peptide fragments are enriched through specific binding of chemically modified magnetic nanoparticles and glycosylated peptide fragments, so that the problems of high cost, complicated operation and limited identification flux are solved; and an efficient, stable and easy-to-operate technical process is provided for research on glycoproteomics. The surface of the magnetic bead is a combination of a mesoporous structure and a quaternary ammonium salt group, so that the selectivity on a glycosylated peptide fragment is remarkably improved, and non-specific adsorption is reduced. The number of N-glycopeptides can be averagely identified to 2733, and the number of O-glycopeptides can be averagely identified to 1777. The enrichment process is simplified by introducing the magnetic beads, and subsequent automatic experiments and large-scale application are facilitated. And the cost is reduced: the preparation and application cost of the material is reduced by simplifying the synthesis method and improving the stability of the material.

A medical centrifuge temperature calibration device relates to the technical field of medical instruments, and comprises a box body, a temperature detection assembly, a refrigeration system and a heating element, the temperature detection assembly is arranged in a working chamber to detect the temperature in the working chamber, the temperature is fed back to a control unit, and the control unit is used for controlling refrigeration to the refrigeration system to reduce the temperature. According to the centrifugal machine, the control unit sends the control instruction to the heating element to heat so as to increase the temperature in the working chamber, so that the temperature in the centrifugal machine is accurately corrected, the requirement for detecting the temperature is met, the centrifugal machine can provide a cultivation environment with the stable temperature, and the use requirement for separation of different biological substances is met.

There is provided a particle for the immunoagglutination assay that is a particle for immunoagglutination assay, which includes a diamond particle and a ligand that specifically binds to a biological substance. The ligand is immobilized to the diamond particle, and the particle for the immunoagglutination assay has a particle size of 50 nm or more and 1,000 nm or less.

A biological substance cumulative amount measurement device 1 for measuring a cumulative amount of a biological substance generated in a living body, said device including: a biofuel cell 20 for generating power using a specific biological substance 13 as a substrate; a power storage unit 40 for storing electric energy generated through power generation by the biofuel cell 20; and a communication unit 50 for outputting information on the electric energy stored in the power storage unit 40 in response to a trigger from the outside.

This biological substance aspiration catheter 1 includes: a catheter body part 10 having an internal lumen 11; and a hollow tip part 20 provided at a tip portion of the catheter body part 10. The hollow tip part 20 includes: a tip-end opening 21 which communicates with the internal lumen 11; a tapered part 22 which is reduced in diameter toward the tip end; and a side port 23 which is provided in the tapered part 22 and communicates with the internal lumen 11. The side port 23 includes: a starting end 24 which is positioned nearer the rear end than the tip part of the tapered part 22 and the tip-end opening 21; and a terminal end 25 which is positioned on the rear end part side of the tapered part 22 or the hollow tip part 20. The side port 23 extends in the axis direction of the hollow tip part 20.

The excitation light source (1) emits excitation light that advances in the optical medium (3) toward the sample (5) placed on the sample placement surface. The probe light source (2) emits probe light advancing in the optical medium (3). The light position detector (4) detects the position of the emitted probe light emitted from the optical medium (3). The arithmetic unit (11) calculates the position of the probe light emitted by the light position detector (4) when the sample (5) is a reference substance that absorbs the excitation light and does not have a specific absorption peak within the excitation wavelength of the excitation light, and the position of the probe light emitted by the light position detector (4) when the sample (5) is a biological substance. The amount or concentration of the biological component in the biological substance is calculated.

The invention relates to the technical field of veterinary drugs, in particular to a composition for preventing and / or treating donkey mastitis and application thereof. The invention provides a composition for preventing and / or treating donkey mastitis. The composition comprises the following components: nisin, lysozyme, a honeysuckle extract, a dandelion extract, a lithospermum extract, an astragalus extract and a frankincense extract. The composition can effectively prevent and / or treat donkey mastitis, the active ingredients of the composition are natural or biogenic substances, the antibacterial mechanism of the composition is unique, bacteria are not easily induced to generate drug resistance, and the composition is safe and free of residues, meets the urgent needs of green, healthy and sustainable development of animal husbandry, and has remarkable clinical application value and wide market prospects.

The invention discloses a metabolite-disease association prediction method, and belongs to the technical field of bioinformatics. According to the method, a metabolite-disease-gene multi-source fusion heterogeneous network is constructed by using metabolite omics information, not only is the relationship among different biological substances considered, but also the problem of matrix sparsity is solved, and a local-global feature extraction model LGDFE is proposed, so that the method has the advantages of being high in robustness and high in robustness. The deep relationship in the multi-source fusion heterogeneous network is extracted from global and local angles, the problem that the deep relationship between metabolites and diseases is difficult to fully excavate in a traditional method is effectively solved, the deep learning algorithm CNN is used for predicting data, features of different levels can be automatically fused, the parameter complexity of a common classifier is reduced, and the classification efficiency is improved. The unknown correlation between the metabolite and the disease can be predicted, the prediction efficiency is improved, the correlation between the metabolite and the disease does not need to be obtained through a large number of experiments, and the experiment cost is remarkably reduced.

To solve ethical and sanitary problems in a simulated thrombus and to improve the elasticity of the simulated thrombus.SOLUTION: The simulated thrombus includes a gel-like blood portion containing simulated blood made of a non-biological substance as a main component, and graphite powder contained in the blood portion.SELECTED DRAWING: Figure 3

The barrel 30 of a suction pump 14 of this medical suction device 1 comprises a first valve part 36 that allows inflow of air from a front space 33 in a first ventilation passage 35 to a rear space 34 when a piston 50 moves rearward, and suppresses outflow of air from the rear space 34 to the front space 33 when the piston 50 moves forward. The piston 50 is provided with a second valve part 52 that allows outflow of air from the rear space 34 in a second ventilation passage 51 to the outside when the piston 50 moves forward, and suppresses inflow of air from the outside to the rear space 34 when the piston 50 moves rearward. The suction pump 14 is capable of generating negative pressure for suctioning a biological substance when the piston 50 moves rearward.

A device for measuring electrical conductivity of target ("Target") comprising blood, a body fluid, a body tissue, a biological substance, a liquid or a solid material, comprising a hollow body having a closed end and an open end; a triboelectric nanogenerator (TENG) disposed within the hollow body; the TENG comprising first and second discs disposed within the hollow body, wherein the first disc is disposed adjacent to the closed end of the hollow body and the second disc is spaced apart from the first disc to define a target chamber within the hollow body; a third disc spaced apart from the second disc towards the open end to define a gap between the second and third discs; a first electrode comprising an electrically conductive material disposed on a side of the third disc opposite the gap; and a second electrode comprising a Target in the target chamber.

The utility model discloses a monitoring device for an intake salt meter of a hypertensive patient, and relates to the technical field of biological substances such as blood and urine. The monitoring device comprises a display, the right side of the display is fixedly connected with a fixing block, the right side of the fixing block is provided with a storage groove, the left side of the storage groove penetrates through the fixing block, a supporting plate is installed in the storage groove, and the upper side and the lower side of the supporting plate are both semi-cylindrical surfaces. A storage groove is formed in the upper portion of the fixing block, a check block is connected into the storage groove, the left side of the check block is fixedly connected with the displayer, the check block is arranged at the position close to the lower side, the right side of the displayer is fixedly connected with a containing shell, and a control mechanism is arranged in the fixing block. And therefore, the display can be supported and fixed on different objects, and meanwhile, the stability after supporting can be ensured, so that the application range of the device is widened.

The utility model relates to the technical field of video optical transceivers, in particular to a video optical transceiver with a waterproof bottom, which comprises a transceiver body, a connector fixedly connected to the surface of the transceiver body, a mounting plate fixedly connected to the surface of the transceiver body, and a waterproof mechanism arranged on the surface of the transceiver body and comprising a rotating seat. And the rotating seat is fixedly connected to the surface of the machine body, a rotating plate is rotationally connected to the surface of the rotating seat, and a first limiting plate is fixedly connected to the surface of the rotating plate. The surface of the connector is sleeved with the waterproof cylinder, the waterproof cylinder extrudes the sealing ring on the connector, the sealing ring seals the waterproof cylinder and the connector, water is prevented from entering the connector through the waterproof cylinder, bacteria and other biological substances are prevented from being deposited on the unused connector, the sanitary use condition of the connector is guaranteed, and the service life of the connector is prolonged. And joint faults are prevented.

A compound having two or more phosphor parts, wherein adjacent phosphor parts are linked by a linking group having a molecular flexibility of 0.510 or less and a cLogP of 6.0 or less, and a labeled biological substance using the compound.

To provide a reaction device capable of maintaining the same dispensing amount accuracy of a chemical liquid between a plurality of array plates.SOLUTION: A reaction device for producing a reaction product of a living body-derived material contained in a spot on an array plate and a target material in a sample liquid includes a container placement section on which a reaction container including the array plate is placed, a chemical solution placement section on which a chemical solution container containing a chemical solution is placed, a pipetter to which a pipette tip is attached and which the chemical solution from the chemical solution container and dispenses the chemical solution into the reaction container, and a control section that changes a dispensing operation of the pipetter according to at least any of a type of the chemical solution, a state of the chemical solution, an operation history of the pipetter, and a state of the pipette tip.SELECTED DRAWING: Figure 1

This container structure is mounted on an array plate having an upper surface on which a spot array including a biological substance is formed, and the container structure is configured so as to form a container that has the array plate as the bottom plate thereof and that is capable of storing liquid, wherein the container structure includes: an embankment portion that forms a side wall of the container when mounted on the array plate; and a retroreflective light attenuating portion that is disposed facing to the array plate to reduce retroreflective incidence of light that has passed through the spot array onto the spot array. This reduces the impact of retroreflective light that has passed through the spot and is scattered forward becoming background light noise.

A compound containing two or more phosphor moieties having light absorption characteristics that are equivalent to each other, in which each of the phosphor moieties adjacent to each other is linked through a group containing a structure represented by General Formula (I), and a labeled biological substance using the compound. In the formula, X1 to X3 represent -O-, -S-, >NR1, or >CR2R3, R1 to R3 and R11 represent a hydrogen atom or a substituent, R8 represents a hydrogen atom or a substituent, n represents an integer of 2 or more, and * represents a bonding site.

The application discloses a preparation method of a material for enriching hydrophilic biological substances, and the core of the method is to perform peptide segment enrichment through specific binding of chemically modified magnetic nanoparticles and glycosylated peptide segments, so that the problems of high cost, complicated operation and limited identification throughput are solved, and an efficient, stable and easy-to-operate technical process is provided for glycoproteomics research. High selectivity: the surface of the magnetic beads is a combination of mesoporous structures and quaternary ammonium salt groups, which significantly improves the selectivity of the glycosylated peptide segments and reduces non-specific adsorption. The number of N-glycans can be identified to an average of 2733, and the number of O-glycans can be identified to an average of 1777. Simple operation: the introduction of the magnetic beads simplifies the enrichment process and facilitates subsequent automated experiments and large-scale applications. Cost reduction: by simplifying the synthesis method and improving the stability of the material, the preparation and application cost of the material is reduced.

A fluorescent compound represented by the following general formula (1) and a fluorescently labeled biological substance using the fluorescent compound. In the above formula, FL represents an n-valent fluorophore moiety, and n is an integer of 1 or more. R 11 ~R 15 represents a hydrogen atom or a substituent. Among them, at least one of the combination of R 11 and R 12 and the combination of R 12 and R 13 is a combination in which one is -SO3 ‑ X + and the other is a substituent. X + represents a hydrogen ion or a metal ion.