Method for coating substrate with antimicrobial agent and product formed thereby

a technology of antimicrobial agent and substrate, which is applied in the direction of aerosol delivery, machines/engines, applications, etc., can solve the problems of inability to adapt, the thickness of the dressing limits the coating process, and the coating method is expensiv

Inactive Publication Date: 2006-02-09
KCI LICENSING INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0010] The present invention fulfills this and other needs through the development of a process for uniformly coating a foam or dressing and a foam

Problems solved by technology

The thickness of these dressings limits the coating process, inasmuch as there is no way to insure a uniform coating throughout the entire structure such that the structure is capable of being severed omni-directionally while still having the desired anti-microbial agent exposed for use in a wound.
However, these coating methods are costly, and are not adaptable to uniformly coating three-dimensional surfaces of cer

Method used

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  • Method for coating substrate with antimicrobial agent and product formed thereby
  • Method for coating substrate with antimicrobial agent and product formed thereby
  • Method for coating substrate with antimicrobial agent and product formed thereby

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Embodiment Construction

[0017] The present invention provides a method for uniformly coating a wound dressing with antimicrobial polymers incorporating agents, such as Au, utilizing a novel process and a wound dressing formed under the process. The method of uniform coating enables a user of the dressing to sever the dressing in any direction and still have all exposed surfaces uniformly coated with the antimicrobial agent sufficient to decontaminate the wound.

[0018] A polyurethane foam is uniformly coated with a silver hydrogel polymer. The polymer coating itself contains PVP or Poly[vinlypyrrolidine], which is a water-soluble polymer with pyrroloidone side groups, typically used as a food additive, stabilizer, clarifying agent, tableting adjunct and dispersing agent. It is most commonly known as the polymer component of Betadine (a povidone-iodine formulation). In addition, the coating may contain Chitosan, which is a deacetylated derivative of chitin, a polysaccharide that is refined from shells of shr...

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Abstract

A method for uniformly coating a foam or dressing with antimicrobial polymer incorporating agents, such as silver, and a foam or dressing formed by this process. Such foam or dressing is particularly useful in combination with negative pressure wound therapy.

Description

CROSS REFERENCE TO RELATED APPLICATIONS [0001] The present application claims priority to U.S. Provisional Patent Application No. 60 / 591,014, filed Jul. 26, 2004, the disclosure of which is incorporated herein by reference.BACKGROUND OF THE INVENTION [0002] 1. Field of the Invention [0003] This invention relates in general to a process for coating reticulated foam, and more particularly but not by way of limitation, to a method for coating reticulated foam with antimicrobial agents that provides uniform coating throughout the reticulated foam and the product formed by the method. [0004] 2. Description of the Related Art [0005] A wide variety of novel and / or established antimicrobial compounds combined with wound dressing can control microbial contamination and potentially lower the rate of infection. The coating uniformity is an essential key to the antimicrobial performance of the wound dressing. What is not known is any method of coating medical wound dressings or foams wherein th...

Claims

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Application Information

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IPC IPC(8): A61K9/14A61K33/38
CPCA61K9/122Y02T10/18A61L15/425A61L15/46A61L15/60A61L2300/104A61L2300/404A61L2300/606F02B1/12F02B2075/125F02D13/0219F02D13/0249F02D13/0265F02D13/0273F02M25/0752Y02T10/121A61K33/38A61K2300/00F02M26/01A61P17/02Y02T10/12A61M1/915A61L15/00
Inventor GINTHER, DEVIN C.
Owner KCI LICENSING INC
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