237 results about "Antimicrobial polymer" patented technology

An antimicrobial composition comprising: a complex of an anionic polyester with an antimicrobial cationic surfactant, wherein the anionic polyester has at least one carboxylic group. A medical device having an antimicrobial composition comprising: a complex of an anionic polyester with an antimicrobial cationic surfactant wherein the anionic polyester has at least one carboxylic group.

A method for uniformly coating a foam or dressing with antimicrobial polymer incorporating agents, such as silver, and a foam or dressing formed by this process. Such foam or dressing is particularly useful in combination with negative pressure wound therapy.

A self-cleaning or lotus-effect surface that has antimicrobial properties, commercial products comprising such a surface, and uses thereof. A process for the production of an antimicrobial self-cleaning or lotus-effect surface in which one or more antimicrobial polymer(s) is secured to a surface-coating system for securing structure-formers to generate a self-cleaning surface. This method lastingly binds antimicrobial polymers to the self-cleaning surface. Commercial products comprising an antimicrobial self-cleaning or lotus-effect surface.

This invention relates to a process for making articles antimicrobial and odor inhibiting, which comprises using vacuum deposition and electron beam techniques to graft amino-reactive functional groups onto polymeric material which the article comprises, followed by contacting the polymeric material with a chitosan solution.

Bactericidal compositions are disclosed that comprise a polymeric compound immobilized on a material. Medical devices are also disclosed which comprise such a bactericidal composition. Methods are disclosed for covalently derivatizing the surfaces of common materials with an antibacterial polycation, e.g., poly(vinyl-N-pyridinium bromide); the first step of the methods involves coating the surface with a nanolayer of silica. Various commercial synthetic polymers derivatized in this manner are bactericidal, i.e., they kill on contact up to 99% of deposited Gram-positive and Gram-negative bacteria, whether deposited through air or water.

A polymer composite comprising a melt-processed polymer compounded with a color stabilizer comprising a bromate or iodate ion, and a silver-based antimicrobial agent. The specified color stabilizers are particularly superior in inhibiting undesirable darkening or discoloration of melt-processed polymers compounded with silver-based antimicrobial agents containing a grain-size controlling additive.

Absorbent dressings, including highly-absorbent dressings having antimicrobial polymer attached thereto via non-siloxane bonds are disclosed. Bandages (i.e. wound dressing), sanitary napkins and the like are useful applications for the intrinsically bactericidal absorbent dressings whose method of manufacture and use are disclosed and claimed.

The present invention discloses a method of dispersing cyclodextrins into a base polymer. The method of the invention comprises reacting grafted microfine polymer powder with a cyclodextrin to form a cyclodextrin-attached grafted polymer, and mixing the cyclodextrin-attached grafted polymer and the base polymer for a sufficient time that the cyclodextrin-attached grafted polymer is dispersed within the base polymer. The present invention also provides several cyclodextrin-inclusion complex products formed by the method of the invention. This products include an antimicrobial polymer blend, a fragrant polymer blend, and a dyed polymer blend.

An alcohol- or glycol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises at least one alcohol or glycol and an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or a metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer. Alternatively, the composition is incorporated into or within the substrate.

The invention relates to sterile medical injection catheter ports utilizing a new antimicrobial polymer mixture filled injection port barrier cover. This barrier cover, when screwed onto the injection port, protects the injection port from the colonization of microbes from the inadvertent contamination of the port with contaminated surfaces, including skin and other potential contaminants.

The present invention provides durable and regenerable antimicrobial fibers and methods for preparing the same. These fibers have excellent colorfastness and washfastness, and are environmentally friendly. The antimicrobial fibers of this invention are suitable for a variety of purposes, including medical uses, sportswear, and uniforms.

Bactericidal compositions are disclosed that comprise a polymeric compound immobilized on a material. Medical devices are also disclosed which comprise such a bactericidal composition. Methods are disclosed for covalently derivatizing the surfaces of common materials with an antibacterial polycation, e.g., poly(vinyl-N-pyridinium bromide); the first step of the methods involves coating the surface with a nanolayer of silica. Various commercial synthetic polymers derivatized in this manner are bactericidal, i.e., they kill on contact up to 99% of deposited Gram-positive and Gram-negative bacteria, whether deposited through air or water.

The present invention relates to the conjugation of antimicrobial agents to water-soluble polymers to improve their clinical properties in terms of their pharmacokinetics, pharmacodynamics, and reduced immunogenicity. More specifically, the present invention relates to the conjugation of antimicrobial agents such as lysostaphin to poly(alkylene oxides), such as poly(ethylene glycol) (PEG).

An antimicrobial polymer is disclosed containing silicon-containing quaternary ammonium groups, the polymer including in its structure repeating units of Formula II:R3N+R0nSiX′4−nY−  (II)wherein each R and each R0 is independently a non-hydrolysable organic group; each X′ is —OR′, —OH or —0—Si, wherein R′ is an alkyl group of 1 to about 22 carbon atoms, or an aryl group of 6 carbon atoms; n is an integer of 0 to 3; and Y is an anionic moiety suitable to form the salt of the repeating units of Formula II. Also disclosed are methods of making such a polymer and imparting sustained antimicrobial properties to a substrate using the polymer.

An improved method of making CASE materials is provided, wherein the method utilizes a polymer latex derived from at least one ethylenically unsaturated monomer and at least one polymerizable surface active agent. The polymerizable surface active agent is capable of co-polymerization with traditional monomers and is preferably substantially completely consumed during the course of the polymerization. Latex polymers produced by the method of the present invention are well suited for use in coatings, adhesives, sealants, elastomers. Additionally, the present invention relates to improved coating, adhesive, sealant and elastomer (CASE) materials utilizing polymer latexes derived from various monomers and ethylenically unsaturated amine salts of sulfonic, phosphoric and / or carboxylic acids.

An alcohol- or glycol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises at least one alcohol or glycol and an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or a metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer. Alternatively, the composition is incorporated into or within the substrate.

A material for use in currency comprises an antimicrobial polymer material which can be used in the manufacture of banknotes having security features therein. The material can be a sheet or substrate and / or an acrylate polymer coat applied to at least one surface of a banknote.

An elastomeric article having reducing microbe affinity and transmission and methods for applying and immobilizing antimicrobial compounds to the elastomeric substrate surface are disclosed. The elastomeric article has a body formed of a natural or synthetic polymer latex having an outer surface and an inner surface. The body has a coating of an antimicrobial agent over at least a portion of said outer surface. The treatment involves applying according to either a spraying or dipping process an antimicrobial polymer or composition to a surface of the elastomeric substrate; binding the antimicrobial composition to the surface in a manner such that said treat antimicrobial coating passes either one or another or both versions of a zone of inhibition test, such test including: a) a dry-leaching or agar-plate-based contact test, according to AATCC 147 protocol, or b) a wet-leaching or dynamic shake flask test according to ASTM E-2149-01 protocol. The substrate is further subject to a rapid germicidal contact-transfer test of relatively short duration. The antimicrobial polymer can include an organosilane quaternary ammonium or a biguanide compound which can disrupt the ionic charges of microbial cellular membranes.

The present invention discloses a method of dispersing cyclodextrins into a base polymer. The method of the invention comprises reacting grafted microfine polymer powder with a cyclodextrin to form a cyclodextrin-attached grafted polymer, and mixing the cyclodextrin-attached grafted polymer and the base polymer for a sufficient time that the cyclodextrin-attached grafted polymer is dispersed within the base polymer. The present invention also provides several cyclodextrin-inclusion complex products formed by the method of the invention. This products include an antimicrobial polymer blend, a fragrant polymer blend, and a dyed polymer blend.

The invention discloses a high molecular weight guanidine salt and polybasic amine antibiosis type polymer and a preparation method and the application thereof. The polymer comprises a repeated unit structure as right, wherein, X1 and X2 are the same or different polybasic amines; Y is Cl<->, NO3<->, HCO3<-> or H2PO4<->; Z is polyprotic acid, polyprotic acid anhydride or multielement ester. When in preparation, the mixture of polynary amine and guanidine salt is heated for reaction, and then polyprotic acid, polyprotic acid anhydride or multielement ester is added, and the temperature is continuously raised for reaction. The invention solves the problem that the polybasic amine and the guanidine salt react through a main body, thereby being difficulty to obtain a higher molecular weight polymer. In lower reaction temperature and shorter reaction time, by the chain expanding reaction to a polynary amine and guanidine salt prepolymer by the polyfunctionality substance, the high molecular weight guanidine salt and polybasic amine antibiosis polymer is formed. The polymer can be used as the anti fungus agent of the fiber product, the paper product, the non-weaving product and the tissue, etc.

Water-absorbing, antimicrobial polymer particles comprising from about 1 to about 500 ppm, based on the particles, of a silver ion based on a silver salt, wherein the silver salt has a solubility product of at least about 1×10−8 (mol / l)m+n; at least about 10 wt. %, based on the polymer particle, of a water-absorbing polymer based on: (α1) from about 50 to about 99.99 wt. % polymerized, ethylenically unsaturated, acid groups-containing monomers or salts thereof, (α2) 0 to about 40 wt. % polymerized, mono-ethylenically unsaturated monomers polymerizable with α1, (α3) from about 0.01 to about 5 wt. %, preferably from about 0.1 to about 3 wt. % of one or more crosslinkers, (α4) 0 to about 30 wt. % of a water soluble polymer and (α5) 0 to about 20 wt. % of auxiliaries, the concentration of the silver ion based on a silver salt in at most about 90 vol. % of the particles is less than about 0.01 ppm.

The invention discloses a preparation method of a quaternary ammonium salt polymer antibacterial agent and a silver-loaded compound antibacterial agent thereof on the basis of an ATRP method. According to the method, various monomers are grafted onto initiation points of an initiator through atom transfer radical active polymerization, a high molecular polymer is obtained, ring-opening reacting is conducted on the high molecular polymer, and an antibacterial agent polymer framework material can be obtained; different modifications are conducted on the antibacterial agent polymer framework material, and a quaternary ammonium salt polymer antibacterial agent, a silver-loaded-quaternary ammonium salt polymer compound antibacterial agent and a silver-loaded polymer antibacterial agent are obtained respectively. The obtained antibacterial agents are low in antibacterial concentration and obvious in sterilizing effect and can be used for modifications of the surfaces of glass sheets, polystyrene and the like by combining the adsorption property of dopamine to form a surface antibacterial polymer brush. The antibacterial effect of the antibacterial agents is obvious, and high commercial potential is achieved.

A bactericidal or antimicrobial polymeric composition includes a hydrophilic first comonomer copolymerized to a second comonomer to produce a polymeric composition that is more hydrophilic or more bactericidal or antimicrobial in an aqueous solution than either of the comonomers alone. Methods for identifying bactericidal or antimicrobial polymers, methods for rendering materials bactericidal or antimicrobial, and methods for using bactericidal or antimicrobial compositions to kill or reduce bacterial or microbial growth are also described. Applications for the inventive compositions include their use in catheters, stents, medical devices, contact lenses; root canal fillers; fibers; paper; and / or wound dressing.

The present invention provides an antibacterial glass composition exhibiting high antibacterial performance with sufficiently sustaining antibacterial performance by adding a small amount of the antibacterial component, and an antibacterial polymer composition using the antibacterial glass composition. The present invention provides an antibacterial glass composition containing 0.1 to 5.0% by weight of Ag2O in a glass composition containing 30 to 60 mol % of P2O5, 1 to 15 mol % of one or more compounds selected from the group consisting of K2O, Na2O and Li2O, 35 to 55 mol % of one or more compounds selected from the group consisting of MgO, CaO and ZnO, and 0.01 to 3 mol % of one or more compounds selected from the group consisting of La2O3 and Y2O3.

One aspect of the present invention is directed to antimicrobial surfaces comprised of hydrocarbon polymers with significant hydrophobic character which also contain an amino group with a pKa greater than or equal to about 8. In certain embodiments initiated chemical vapor deposition (iCVD) is used to coat a surface with an antimicrobial polymer.

The present invention provides a particle comprising at least one aliphatic polymer having anti-microbially active quaternary ammonium groups chemically bound thereto. The particle of the invention may be used to inhibit populations of microorganisms and biofilms. Also provided are methods for the preparation of such particles and uses thereof for the inhibition of microorganisms.

The invention discloses an antibacterial polymer material which is polymerized by a plurality of components including antibacterial oligomer. The specific components comprise 30-99.5wt percent of unsaturated double bond monomer, 0.01-50wt percent of unsacturated double bond antibacterial oligomer, 0-10wt percent of hydrophilic monomer, 0.01-5.0wt percent of polymerization initiator and 0-80wt percent of fillings. The antibacterial polymer material of the invention is safe to the health of people and has long antibacterial performance and the antibacterial rates of the invention to staphyloccocus aureus rosenbach and escherichia coli are both more than 99percent. The invention is applicable for medical treatment and hygiene industries, including the wound dressing material, dental recovery materials used in dentistry (such as tooth bonder, tooth recovery coating, tooth recovery substrate and tooth filling materials, etc.), surgery seam and materials for daily use, etc.

The present invention relates to a antimicrobially-treated porous materials and a process for impregnating porous materials with antimicrobial polymers using supercritical media.