69 results about "Antimicrobial polymer" patented technology

The invention discloses a hydrophobic antibacterial polymer, a preparation method and application in a hydrophobic antibacterial coating, and belongs to the technical field of high polymer materials, and the preparation method comprises the following steps: mixing a component A with a first organic solvent to obtain a solution 1, and mixing a component B with a second organic solvent to obtain a solution 2; blending the solution 1 and the solution 2, adding a component C and an initiator, and reacting to obtain a hydrophobic antibacterial polymer; dissolving the hydrophobic antibacterial polymer in a third organic solvent to obtain a solute solution; and coating the surfaces of fabrics, silicon wafers, steel and wood with the dissolved matter solution through spraying, dispensing and dipping, and curing to obtain the self-healing high-durability hydrophobic antibacterial coating capable of being freely coated. The preparation method disclosed by the invention is simple in process and low in cost, the obtained coating has excellent hydrophobicity, antibacterial property and environmental stability and also has self-repairing property and free coating property, and the service life and the use convenience of the coating are remarkably improved.

Methods of and apparatuses for the manufacture of biomimetic physical antimicrobial polymer foils are disclosed. An example method of manufacturing includes providing a substrate. The method additionally includes depositing an aluminum-containing layer on the substrate. The method yet further includes anodizing an exposed surface of the aluminum-containing layer in a first bath so as to form a plurality of pores in the exposed surface of the aluminum-containing layer. Moreover, the method includes immersing the exposed surface of the aluminum-containing layer in a second bath, further etching the plurality of pores in the exposed surface of the aluminum-containing layer. Methods also include formation of templated polypropylene and cellulose films.

An antibacterial polymer having a molecular weight above a certain level, which is highly miscible with other polymers compared to a monomolecular type antibacterial agent and can be added during the melt extrusion process. Further the antibacterial polymer has the advantage of exhibiting excellent antibacterial properties against Gram-negative bacteria and does not elute over time.

The invention relates to double-layer hydrogel for scar-free corneal injury repair and a preparation method of the double-layer hydrogel. The preparation method comprises the following steps: (1) synthesizing oxidized polysaccharide and a sulfhydrylated polymer; the method comprises the following steps: oxidizing polysaccharide by taking NaIO4 as an oxidizing agent to obtain oxidized polysaccharide; wherein the oxidized polysaccharide is negatively charged; the preparation method comprises the following steps: modifying an amino-containing antibacterial polymer by using cysteine to obtain a sulfhydrylated polymer; (2) preparing bottom layer hydrogel; amino of the multi-arm polyethylene glycol and oxidized polysaccharide are subjected to a Schiff base reaction, and amino of the multi-arm polyethylene glycol and a multi-arm polyethylene glycol derivative are subjected to a cross-linking reaction, so that bottom-layer hydrogel is formed; wherein the multi-arm polyethylene glycol derivative has a group crosslinked with an amino group; (3) preparing double-layer hydrogel; and spraying the sulfhydrylation polymer on the bottom layer hydrogel, and carrying out UV illumination to obtain the double-layer hydrogel. According to the double-layer hydrogel disclosed by the invention, the purposes of resisting bacterial infection, regulating cascade immunoreaction, reducing scar formation and recovering cornea transparency are achieved through the cooperation of structural design, a biological mechanism and a time sequence.

The invention discloses a photoresponse-essential oil synergistic antibacterial polymer and an application thereof in resisting multiple drug-resistant bacteria. Citronellol (CT) is subjected to an esterification reaction to prepare a CMA monomer, the CMA monomer and a glycidyl methacrylate (GMA) monomer are copolymerized to prepare a polymer PG9C2, and then TBO is introduced to obtain the antibacterial polymer PG9C2T1. The improvement of the antibacterial activity of the TBO is derived from the improvement of the fat solubility of the TBO, the enhancement of the interaction between the TBO and bacterial cells, the improvement of the accumulation of the TBO in the cells, the penetration of the TBO through cell membranes and the play of roles in the cells, the improvement of the utilization efficiency of ROS, and the sterilization by improving the water solubility of the essential oil through the mechanism of destroying bacterial membranes. According to the invention, high-efficiency and low-toxicity drug-resistant bacteria based on natural products are synthesized, the limitation of a single antibacterial mode is broken through, and technical support is provided for developing a novel low-drug-resistance antibacterial therapy.

The invention relates to an odorless antibacterial polymer-based composite material and a preparation method thereof. The odorless antibacterial polymer-based composite material comprises the following components in parts by weight: 20-30 parts of modified water-borne epoxy resin, 5-20 parts of a water-borne epoxy resin curing agent, 5-10 parts of a dispersing agent, 5-10 parts of a defoaming agent, 5-10 parts of a flatting agent, 5-10 parts of a coalescing agent, 5-10 parts of modified glass fibers, 20-30 parts of filler, 5-10 parts of an antibacterial agent, 3-8 parts of an antioxidant and 20-30 parts of water. The coating has excellent properties, such as good adhesiveness, corrosion resistance, good mechanical properties, good antibacterial property, good weather resistance, water resistance and the like. And the modified tetrapod-like zinc oxide whisker is compounded with the ethylene bis-dithiocarbamic acid zinc, so that the problem of poor compatibility with the odorless antibacterial polymer-based composite material when the modified tetrapod-like zinc oxide is independently added is solved, the surface hardness of the odorless antibacterial polymer-based composite material is increased, and the service life of the odorless antibacterial polymer-based composite material is prolonged.

The present invention belongs to the technical field of antimicrobial polymer materials, and discloses a poly(acrylamide-methacrylamide primary amine salt) with a random structure, a preparation method thereof, and an application thereof. The poly(acrylamide-methacrylamide primary amine salt) with a random structure has a structural formula as shown in Formula 1: #imgabs0# wherein both m and n are positive integers, and m:n=1:(0.1-9). The poly(acrylamide-methacrylamide primary amine salt) with a random structure has a good antibacterial effect, particularly an inhibitory effect on Foc4 spores. After application to soil, it can be stably adsorbed in the soil, with reduced environmental toxicity, and while improving the physical and chemical properties of the soil, it can achieve long-term inhibition of Foc4 spores in the soil, thereby having a good preventive and control effect on plant fungal diseases such as banana wilt.

The invention relates to the technical field of high polymer material processing, in particular to an antimicrobial high polymer material product and a preparation method thereof.The antimicrobial high polymer material product is obtained by applying photon broadband antibacterial treatment to the high polymer material product; the high polymer material comprises plastic or rubber, the plastic comprises polyethylene or polyvinyl chloride, and the rubber comprises butyronitrile; the high polymer material product is an elastomer product; the elastomeric articles include glove fingerstalls, dams, probe sleeves, or medical catheters. The antimicrobial high polymer material product has an excellent inhibition effect on staphylococcus aureus, escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa, candida albicans and the like, the antibacterial rate can reach 89% or above, the preparation process is simple, the cost is controllable, and the antimicrobial high polymer material product is suitable for industrial production.

The present invention discloses a method for preparing an antibacterial polymer with a low antibacterial agent content and a coating structure, comprising: melt-blending and extruding an antibacterial agent with matching polarity and a coating layer polymer; and co-injecting the extruded product with a core layer polymer having a certain polarity and viscosity difference under specific conditions to obtain the antibacterial polymer with a low antibacterial agent content and a coating structure. The method prepares a polymer antibacterial composite material with a coating structure, and the antibacterial agent is selectively distributed in the coating layer polymer. While ensuring high antibacterial efficiency, the amount of the antibacterial agent used is greatly reduced, the cost is low, the preparation process is simple, and it is easy to industrialize.

The present application discloses an antimicrobial nylon material, along with its preparation method and application. The present application relates to the technical field of antimicrobial polymer materials and addresses the limitations of existing antimicrobial nylon 6, particularly its insufficient antimicrobial efficacy and challenges in scalability for industrial production. In the present application, a seven-membered cyclic lysine-derived monomer is copolymerized with a lactam via hydrolytic copolymerization using water as an initiator, yielding a copolyamide. The resulting copolyamide is then subjected to a protonation reaction through heating and stirring in an acidic solution, followed by purification to obtain the final antimicrobial nylon material. The seven-membered cyclic lysine-derived monomer may be an unprotected cyclic lysine monomer, a mono-protected cyclic lysine monomer, or a salt form cyclic lysine monomer. The present invention exhibits broad applicability in antimicrobial-sensitive fields such as textiles, plates, pipes, packages or panels.

The present invention relates to an antibacterial polymer composition containing a polymer compound in which a cationic monomer and a fluorine-based acrylic monomer are graft-polymerized in a fluorine-based copolymer. A fluorine-based polymer composition according to the present specification exhibits an antibacterial effect of 99.9% or more, exhibits a contact angle of 150 degrees or greater with respect to a solvent, and thus can be applied to a coating agent exhibiting high air permeability, contamination resistance, and antibacterial effect.

The present invention relates to a polymer, containing a structural unit A′ derived from a monomer A and a moiety B′ derived from a compound B, wherein monomer A contains a nitrogen atom and a polymerizable carbon-carbon double bond, and compound B is selected from a group consisting of bicyclic monoterpenes, monocyclic monoterpenes, acyclic monoterpenes, and C1-10 alkyl-substituted phenol, wherein the bicyclic monoterpene is selected from pinene-based compounds containing hydroxy, carene-based compounds containing hydroxy, chrysanthanol, and fenchol. The present invention further relates to processes of preparing the polymer.

The present invention relates to the field of polymer materials. Disclosed are an isobutylene-based cationic salt ionic polymer, a preparation method therefor, and the use thereof. The polymer comprises a structure represented by formula (2) and / or formula (3), and optionally, a structural unit A represented by formula (1), a structural unit B represented by formula (4) and a structural unit C represented by formula (5), Q being formula (6), formula (7), formula (8) or formula (9). The side group and the main chain of the polymer both contain cationic salt groups, so that the polymer has a high polyionic degree and thus can be used as an antibacterial agent for preparing antibacterial polymer materials, such as antibacterial plastics, antibacterial rubber, antibacterial fibers and antibacterial coatings.

Disclosed herein are PEG-maximin H5 peptide conjugates and methods for using the same in the treatment or prevention of biofilms and biofouling.

The present invention provides an antibacterial structure comprising: a polymeric support layer carrying an antibacterial component; and an antibacterial polymeric layer applied onto the support layer. The antibacterial structure according to the present invention exhibits an excellent antibacterial effect, shows a contact angle of 150° or higher with a solvent even if the antibacterial component is carried, and has antifouling properties.

Antibacterial compositions, such as antibacterial masterbatches, powders, liquid dispersions, may include a mixture of at least one antibacterial metal compound and at least one synergistic compound. For example, the antibacterial composition may include at least one antibacterial metal compound and a boron compound, a mixture of powders, or a liquid dispersion blended into a masterbatch. The composition may further include at least one pH adjuvant that creates an acidic environment inside or outside the composition. It has been surprisingly found that these components produce a synergistic relationship within the composition that provides a more tailored antimicrobial polymer composition or article.

The application provides a guanidine-containing antibacterial polymer, a preparation method and application thereof, and has the structure shown in the following formula I. When a nanofiber membrane prepared from the guanidine-containing antibacterial polymer is used to filter PM in air, the nanofiber membrane has good filtering effect, and has good bacteriostatic effect on staphylococcus aureus and escherichia coli, and even has better bacteriostatic effect when stored for a long time.

The invention belongs to the field of non-woven materials, and particularly relates to an antibacterial polylactic acid melt-blown non-woven material and a preparation method thereof. The antibacterial polylactic acid melt-blown non-woven material provided by the invention comprises the following components: polylactic acid and an antibacterial polymer, the antibacterial polymer is one or more of polymers with structures as shown in formulas (I)-(IV). The novel N-halamine / quaternary ammonium salt composite antibacterial polymer is added into the polylactic acid melt-blown non-woven material, the composite antibacterial polymer can play a synergistic bactericidal role of various antibacterial agents, the application defect of a single antibacterial agent is overcome, and therefore the antibacterial performance of the polylactic acid melt-blown non-woven material is remarkably improved. The polylactic acid melt-blown non-woven material provided by the invention is simple and convenient in preparation process, excellent in antibacterial property, excellent in waste degradation property after being used, and good in practical value and environmental protection benefit. # imgabs0 #

The present disclosure relates to an antibacterial polymer composition, more specifically, to an antibacterial polymer composition enabling preparation of a coating layer exhibiting excellent antibacterial property. The antibacterial polymer composition may use a polymer including a specific number of repeat units as an antibacterial agent. Accordingly, unlike coating compositions using antibacterial monomers / antibacterial oligomers, elution of an antibacterial agent from the coating layer may be prevented even after time passes, and thus, it can continuously exhibit antibacterial property, and yet, is difficult to be absorbed in human body.

The invention discloses a biodegradable antibacterial polymer as well as a preparation method and application thereof, and belongs to the technical field of antibacterial agent synthesis. A plurality of brand new antibacterial polymer molecules are obtained through molecular design and synthesis condition optimization, antibacterial polymer molecules with the best comprehensive performance of antibacterial effect and safety are obtained through antimicrobial and compatibility screening, and the molecules show very strong broad-spectrum antibacterial activity under the low-concentration condition and have good antibacterial activity. And the antibacterial polymer is superior to currently known antibacterial polymers and common antibacterial agents. The preparation method comprises the following steps: dissolving 1, 4-p-dibenzyl chloride in a prepared organic solvent; dropwise adding N, N, N ', N'-tetramethylethylenediamine; stirring and reacting for 15 to 24 hours at 85 to 100 DEG C; after the reaction is finished, filtering to obtain a filter cake; and leaching the filter cake to obtain a series of antibacterial polymers. The molecules are prepared from starting materials which are easy to obtain and low in cost on the market, and a simplified polymerization and separation condition method developed by the invention is adopted, so that the production cost is effectively reduced, and the product has relatively good universality.

The present application relates to a kind of odorless antibacterial polymer-based composite and its preparation method.The odorless antibacterial polymer-based composite includes the following components, by weight parts:20~30 parts modified waterborne epoxy resin, 5~20 parts waterborne epoxy resin curing agent, 5~10 parts dispersing agent, 5~10 parts defoaming agent, 5~10 parts leveling agent, 5~10 parts film forming aid, 5~10 parts modified glass fiber, 20~30 parts filler, 5~10 parts antibacterial agent, 3~8 parts antioxidant, 20~30 parts water.The present application has excellent performance, such as good adhesion, corrosion resistance, good mechanical properties, good antibacterial property, good weather resistance, water resistance, etc.Because modified four acicular zinc oxide whisker is compounded with zinc ethylene bisdithiocarbamate, the problem of poor compatibility with odorless antibacterial polymer-based composite when modified four acicular zinc oxide is added alone is also changed, and the surface hardness is also increased, thereby increasing the service life.

The invention "Manufacturing an antibacterial nanocomposite coating based on water-based polyurethane / double hydroxide layer reinforced with an antimicrobial copolymer with the ability to prevent bacterial growth" relates to the field of the medical industry, coatings and coverings; and also relates to the field of medical equipment for the production of antibacterial polymer nanocomposites that inhibit bacterial growth. This nanocomposite coating consists of three different layers with antibacterial properties, each layer performing a different function in destroying bacteria. The first layer uses water-based polyurethane modified with chitosan and polyvinyl alcohol; the second layer uses layered double hydroxide modified with the antibacterial agent cetyltrimethylammonium bromide (cetolone); and finally, the third layer uses an antimicrobial polypropylene-ethylene copolymer (PP-R), which are mixed together to form an antibacterial nanocomposite coating.

This invention relates to the field of medical polymer materials technology, specifically disclosing an antibacterial and antifouling medical coating material and its preparation method. The medical coating material comprises raw materials: a hydrophilic monomer, a fluorinated low surface energy monomer, an antibacterial polymer, a crosslinking agent, a photoinitiator, and a mixed solvent. The antibacterial polymer is obtained by reacting ε-polylysine sequentially with glycidyl methacrylate, 1-bromododecane, and hyaluronic acid oligomers. This invention utilizes in-situ copolymerization cured by ultraviolet light to covalently integrate the functional components into a chemically crosslinked polymer network. The resulting coating surface is highly hydrophilic, effectively resisting non-specific adhesion of proteins and bacteria. It also exhibits specific enzyme responsiveness, displaying low activity and high biocompatibility under normal physiological conditions, but being activated in a microenvironment rich in hyaluronidase caused by bacterial infection, demonstrating a highly efficient bactericidal ability exceeding 99.5% against Staphylococcus aureus and Escherichia coli.

The present invention discloses an anti-biofouling ultrafiltration membrane containing a natural antibacterial material derivative, and its preparation method and application. The preparation method of the anti-biofouling ultrafiltration membrane of the present invention is as follows: (1) synthesizing an antibacterial material capsaicin derivative and transforming the membrane matrix through atom transfer radical polymerization (ATRP); (2) combining the capsaicin derivative with the transformed membrane matrix through an esterification reaction to obtain an antibacterial polymer; (3) subjecting the above polymer to non-solvent induced phase separation (NIPS) to prepare an anti-biofouling ultrafiltration membrane. The process of the present invention is simple, easy to operate, and cost-controlled, and can achieve large-scale industrial production. The anti-biofouling ultrafiltration membrane prepared by the present invention uses a natural antibacterial material derivative. While ensuring safety and friendliness to the environment and humans, it exhibits excellent ability to resist the growth and proliferation of microorganisms on the membrane surface and has good application prospects in water treatment processes.

The present invention relates to a composition comprising a polyimidazolium (PIM) compound for use in the treatment and / or prevention of mastistis in a mammal, and to methods of use.

The present invention relates to the field of polymeric materials and discloses an isobutylene-based cation salt ionic polymer, and its preparation and use. The polymer comprises a structure represented by formula (2) and / or formula (3), optionally including a structural unit A having a structure represented by formula (1), a structural unit B having a structure represented by formula (4), and a structural unit C having a structure represented by formula (5). By containing cation salt functional groups in both the side groups and the main chain of the polymer, the polymer has a high degree of polyionization and can be used as an antibacterial agent to prepare antibacterial polymeric materials such as antibacterial plastics, antibacterial rubber, antibacterial fibers, and antibacterial paints. [Formula 1] TIFF2025535581000053.tif68169 (Q is [chemical 2] TIFF2025535581000054.tif33169 )

The invention discloses a hydrophilic antifogging film which comprises a base material layer and a hydrophilic antifogging layer which are stacked, and the hydrophilic antifogging layer is formed by coating the surface of the base material layer with hydrophilic antifogging coating liquid and carrying out thermocuring. The hydrophilic antifogging coating liquid comprises 1-6 parts of an antibacterial polymer, 7-17 parts of polyvinyl alcohol, 1-3 parts of a silane coupling agent, 0.05-0.2 part of a cross-linking agent, 0.02-0.1 part of a curing agent, 1-4 parts of an auxiliary agent and 80-90 parts of deionized water; the antibacterial polymer is obtained by carrying out protonation reaction on a prepolymer obtained by reacting dimethylaminoethyl methacrylate and acrylic acid and 1-bromo-n-alkane; and the carbon chain length of alkane in the 1-bromo-n-alkane is 7-12. The antibacterial polymer and the polyvinyl alcohol are compounded, so that the hydrophilic anti-fog layer is endowed with good antibacterial property, antifouling property and wear resistance; the crosslinking agent and the curing agent are combined, so that the polymerization crosslinking density of the hydrophilic anti-fog layer is improved, and the durability, the wear resistance and the adhesive force of the anti-fog function are further improved.

The present application provides an exosome-integrated antimicrobial polymer material and its preparation method, belonging to the field of intelligent biomimetic materials. The method comprises: introducing a benzimide bond into the molecular structure of a polylysine-chitosan copolymer to obtain a first copolymer; covalently coupling D-glutamic acid and electrostatically adsorbing a lipoteichoic acid-binding peptide to obtain a second copolymer; mixing a phosphate buffer solution of aldehyded methylcellulose and a phosphate buffer solution of amino-modified chitosan to obtain a first mixture; adding a mixture of protocatechualdehyde and FeCl3 solution to the first mixture to obtain a second mixture; and adding the second copolymer, placental mesenchymal stem cell exosomes, and Ag@rGO nanoparticles to the second mixture under stirring, and allowing the mixture to stand to obtain the exosome-integrated antimicrobial polymer material. This method simultaneously improves the antimicrobial, repair, mechanical, and environmental responsiveness of the exosome-integrated antimicrobial polymer material.