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Oral compositions containing oxidized camellia

a technology of camellia and oral compositions, applied in the field of biofilms, to achieve the effect of enhancing the inhibition of the attachment of bacterial film to the teeth and enhancing the removal of bacterial film

Inactive Publication Date: 2006-06-29
COLGATE PALMOLIVE CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0008] It has been discovered that compositions and methods of this invention afford advantages over oral care compositions known in the art, including one or more of enhancing the inhibition of bacterial film attachment to the teeth; and enhancing the removal of bacterial film from the teeth. Further uses, benefits and embodiments of the present invention are apparent from the description set forth herein.

Problems solved by technology

Plaque mineralizes to form a hard deposit called calculus, which becomes a local irritant for the gums, causing gingivitis.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0059] A dentifrice composition of the present invention is made by combining the following ingredients:

[0060] Table 1: Dentifrice composition according to the present invention, which includes PVM / MA copolymer.

INGREDIENTWEIGHT %Glycerin19.0Sorbitol21.0Propylene Glycol0.5Carboxymethylcellulose1.1Carageenan0.4Saccharin0.3Sodium fluoride0.243Titanium dioxide0.5PVM / MA2Sodium hydroxide (50%)1.2Silica21.5Sodium lauryl sulfate1.5Flavor1.0Oolong tea extract1.0Water to make 100%

The resulting dentifrice is a toothpaste that can be applied to the oral surfaces with a brush or other applicator.

[0061] The oral composition of Table 1, which includes PVM / MA copolymer, inhibits plaque from adhering to oral surfaces. It was surprising to learn that the PVM / MA copolymer boosts the effect of larger, more complex polyphenols present in the extract of semi-oxidized tea from genus Camellia. The polyphenols inhibit biofilm formation by interfering with the bacterial enzyme glucosyltransferase, which...

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Abstract

Oral composition comprising a Camellia extract of semi-oxidized tissue from a member of the genus Camellia and an enhancing agent.

Description

CROSS REFERENCE TO RELATED APPLICATION [0001] This application claims priority to U.S. Provisional Patent Application No. 60 / 639,169 filed Dec. 23, 2004, the contents of which are incorporated herein by reference.BACKGROUND OF THE INVENTION [0002] Dental plaque is a biofilm that adheres to tooth and other oral surfaces, particularly at the gingival margin. Dental plaque is cohesive and highly resistant to removal from teeth and / or oral surfaces. Dental plaque comprises glucans, which are insoluble polysaccharides that provide plaque with its cohesive properties. The bacterial enzyme glucosyltransferase converts dietary sugar into glucans. Plaque mineralizes to form a hard deposit called calculus, which becomes a local irritant for the gums, causing gingivitis. [0003] Current treatments for removing and preventing plaque build-up include brushing the teeth with an abrasive and / or antibacterial toothpaste, flossing, and various other treatments. The effectiveness of such treatments de...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K9/14A61K36/82
CPCA61K8/8164A61K8/97A61K36/82A61Q11/00A61K2300/00A61K8/9789A61P1/02A61P31/04
Inventor BOYD, THOMAS J.GAFFAR, ABDULVISCIO, DAVID
Owner COLGATE PALMOLIVE CO
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