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Formulations And Treatments For Trichology

a technology of trichology and formulations, applied in the field of trichology formulations and treatments, can solve the problems of complex alopecia condition, unrecognized root causes, and inability to fully understand other root causes, etc., to achieve the effect of reducing the catagenic and/or telegenic phases, promoting the anagenic phase of hair growth, and inhibiting the production of patients

Inactive Publication Date: 2008-08-28
DOLPHST PTY LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0090]preparing a predetermined quantity of a second formulation for topical application, the second formulation consisting of: a hair growth component for promoting the anagenic phase of hair growth and / or minimising the catagenic and / or telegenic phases of hair growth; a hair growth component complement for complementing the functional qualities of the hair growth component; a metabolism-balancing component for balancing the metabolism of the patient; a 5-alpha reductase production inhibitor for inhibiting the patient's production of 5-alpha reductase; an amino acid complement providing substantially all of the amino acids required for metabolism of the patient; a nitric oxide metabolite from which nitric oxide may be produced in the metabolic processes of the patient; a keratinocyte cell supplement for supplementing nutrients for the patient's keratinocyte cells; a carbohydrate metabolism facilitator for facilitating carbohydrate metabolism of the patient; a hair cortex elasticity component for enhancing the elasticity of the hair cortices of the patient; an enzymatic antioxidant and detoxifying component for detoxifying the patient, including the scavenging of oxidants; a mineral anti-oxidant component for supplementing the enzymatic antioxidant and detoxifying component; and an immunoglobulin and growth-factor supplement for supplementing the patient's intake of immunoglobulin and growth factor.

Problems solved by technology

However, the interaction of the constituent compounds in such formulations with one another is little understood.
Other root causes are not well understood and / or subject of conjecture.
There is a quantity of research data on efficacy, some of which is in conflict, indicating that the alopecia condition is complex, and is probably affected by a range of different mechanisms.
Some root causes are expressed or exhibited more than others, but unless several of such root causes are addressed by a proposed remedy, it is suggested that its efficacy may be limited.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0118]A batch of material was formulated according to the details set forth in Table 1 below.

mg per gweightIngredient (andLabel(includingfor mixstrength)Claimmgmg / doseoverageoverage)(kg)phytosterols (equiv. B-500.0030315153%312.0935.344sitosterol 33%)Polygonum1350.0067.5337.55%70.888.027multiflorum (fo ti) root4:1 in 70% EWGlycine max (soy) seed1625.005250%5.000.56665:1 in 75% EWGingko biloba leaf ext100.000.425%0.420.048(50:1 in 70% EW)Panax quinquefolium100.056.6733.355%7.000.793root ext (3:1 in 15%EW)Equisetum arvense herb100.005255%5.250.595ext (horsetail) (4:1 in100% water)inositol150.00301505%31.503.567methylsulfonylmethane1000.0020010005%210.0023.783(MSM)colostrum (bovine)1000.0020010005%310.0023.783arginine250.00502500%50.005.663biotin1.400.281.45%0.290.033nicotinic acid15.003155%3.150.357calcium pantothenate200.00402004%41.674.719pyridoxine255255%5.240.595hydrochlorided-α-tocopherol acetate400 IU107.25365%112.5612.747(dry vitamin E acetate)Trusil natural132.6135%2.730.309le...

example 2

[0120]A batch of material was formulated according to the details set forth in Table below.

LABEL CLAIMINGREDIENT(mg per 5 g serve)MgMg / DosePhytosterols (Equiv B-sitosterol 33%)125.0075.75378.75Polygonum multiflorum (Fo Ti) root 4:1 in 70%337.5016.8884.38EWGlycine Max (Soy) seed 65:1 in 75% EW406.251.256.25Ginkgo Biloba leaf ext (50:1 in 70% EW)25.000.100.50Panax quinquefolium root ext (3:1 in 15% EW)25.011.678.34Equisetum arvense herb Ext (Horsetail) (4:1 in25.001.256.25100% Water)Inositol37.507.5037.50Methylsulfonylmethane (MSM)250.0050.00250.00Colostrum (Bovine)250.0050.00250.00Arginine62.5012.5062.50Biotin0.350.070.35Nicotinic Acid3.750.753.75Calcium Pantothenate50.0010.0050.00Pyridoxine Hydrochloride6.251.256.25d-alpha tocopheryl acetate (Dry Vitamin E Acetate)100 IU26.80134.00Trusil Natural Lemon / Lime3.250.653.25Fructose62.5012.5062.50Silica - Colloidal Anyhydrous31.256.2531.25Zinc Amino Acid Chelate 20%5.005.0025.00Total1706.11280.161400.81

[0121]The resulting formulation was t...

example 3

[0122]A batch of material was formulated according to the details set forth in Table 3 below.

LABEL CLAIMINGREDIENT(mg per 5 g serve)MgMg / DosePhytosterols (Equiv B-sitosterol 33%)250.00151.50757.50Polygonum multiflorum (Fo Ti) root 4:1 in 70%675.0033.75168.75EWGlycine Max (Soy) seed 65:1 in 75% EW812.502.5012.50Ginkgo Biloba leaf ext (50:1 in 70% EW)50.000.201.00Panax quinquefolium root ext (3:1 in 15% EW)50.033.3416.68Equisetum arvense herb Ext (Horsetail) (4:1 in 100% Water)50.002.5012.50Inositol75.0015.0075.00Methylsulfonylmethane (MSM)500.00100.00500.00Colostrum (Bovine)500.00100.00500.00Arginine125.0025.00125.00Biotin0.700.140.70Nicotinic Acid7.501.507.50Calcium Pantothenate100.0020.00100.00Pyridoxine Hydrochloride12.502.5012.50d-alpha tocopheryl acetate (Dry Vitamin E Acetate)200 IU53.60268.00Trusil Natural Lemon / Lime6.501.306.50Fructose125.0025.00125.00Silica - Colloidal Anyhydrous62.5012.5062.50Zinc Amino Acid Chelate 20%10.0010.0050.00Total3412.23560.332801.63

[0123]The resul...

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PUM

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Abstract

a formulation for trichological treatment of a patient including, in a dosage in the range of 3 g to 8 g: phytosterols in the range of 200 mg to 2500 mg; the quantitative equivalent of Polygonum multiflorum root 4:1 in 70% EW in the range of 600 mg to 2600 mg; methylsulfonylmethane in the range of 500 mg to 2000 mg; and bovine colostrum in the range of 500 m to 2000 m.

Description

FIELD OF INVENTION[0001]THIS INVENTION relates to formulations and treatments for trichology. The invention is primarily directed to formulations and treatments for reduction of hair loss and / or hair regrowth typically exhibited in adult humans having a condition sometimes referred to alopecia. Although the condition is more prevalent in human males and is sometimes referred to as male pattern alopecia, the invention is applicable to treatment of both male and female alopecia.BACKGROUND ART[0002]Herbal extracts and formulations have been suggested for the trichological treatment of humans, particularly males, but not exclusively so. Efficacy varies from nil to some reduction in hair loss and / or noticeable hair regrowth on the heads of patients. However, the interaction of the constituent compounds in such formulations with one another is little understood. The respective modes of action of such formulations are quite diverse. Generally, such treatments are either topical or systemic...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K35/20A61P17/00
CPCA61K8/27A61K8/44A61Q7/00A61K2800/58A61K36/889A61K36/736A61K36/704A61K36/48A61K36/258A61K36/16A61K36/11A61K35/20A61K31/56A61K31/10A61K8/986A61K8/97A61K8/63A61K8/466A61K8/4906A61K8/58A61K2300/00A61K8/9741A61K8/9771A61K8/9789A61K8/9794A61P17/00A61P17/14A61P3/00A61P3/02A61P9/00
Inventor PHILLIPS, JON
Owner DOLPHST PTY LTD
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