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Novel burn treatment composition

Inactive Publication Date: 2008-08-28
HEALING SKIN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0019](g) stabilizing the pH of the mixture ob

Problems solved by technology

Skin burns result in dyskeratotic cells, spongiosis, vacuolation of keratinocytes and edema from capillary leakage.
As a consequence, skin burns may be very painful.
Furthermore, blisters may develop and scabs and scars may result.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example

Example 1

[0038]One example of the composition of the present invention is shown in Table II

NO.PHASEINCI DESIGNATIONWEIGHT1AWATER (AQUA)50.742ADISODIUM EDTA0.103APENTYLENE GLYCOL3.004ACETYL HYDROXYETHYLCELLULOSE0.255AGLYCERIN1.356BCETEARYL ALCOHOL CETEARETH-204.007BDIMETHICONE0.508BOCTYLDODECANOL BEESWAX0.509BCYCLOPENTASILOXANE1.00POLYSILICONE-11BSTEARYL ALCOHOL0.5010B#N / A5.0011BBEHENTRIMONIUM METHOSULFATE4.00CETEARYL ALCOHOL12BCAPRYLIC / CAPRIC TRIGLYCERIDE3.0013BBISABOLOL0.1014BTOCOPHERYL ACETATE2.00BBEHENYL ALCOHOL0.5015BCAPRYLYL GLYCOL0.8016CLIDOCAINE HCL4.0017CWATER (AQUA)10.0018DALOE VERA GEL1.0019DARNICA MONTANA FLOWER1.00EXTRACT ISI20DCHAMOMILA RECUTITA0.50(MATRICARIA) FLOWER EXTRACTACTIVE ORGANICS21DCALENDULA EXTRACT0.5022DSODIUM HYALURONATE2.0023DETHYLHEXYL GLYCERIN1.0024EPOLYQUATERNIUM-372.0325E20% NAOH0.64

[0039]Phase “A” water is heated to 75° C. Natrasol, a thickening agent, is dispersed and is mixed with water for one hour. Remaining phase A ingredients are added. Phase B...

example 2

[0040]One example of the composition of the present invention is shown in Table II

NO.PHASEINCI DESIGNATIONWEIGHT1AWATER (AQUA)50.702ADISODIUM EDTA0.103APENTYLENE GLYCOL3.004ACETYL HYDROXYETHYLCELLULOSE0.255AGLYCERIN1.356BCETEARYL ALCOHOL CETEARETH-204.007BDIMETHICONE0.508BOCTYLDODECANOL BEESWAX0.509BCYCLOPENTASILOXANE1.00POLYSILICONE-1110BCROCADOL S950.5011BCYCLOPENTASILOXANE5.0012BBEHENTRIMONIUM METHOSULFATE4.00CETEARYL ALCOHOL13BCAPRYLIC / CAPRIC TRIGLYCERIDE3.0014BBISABOLOL0.1015BTOCOPHERYL ACETATE2.0016BBEHENYL ALCOHOL0.5017BCAPRYLYL GLYCOL0.8018CLIDOCAINE HCL4.0019CWATER (AQUA)10.0020DALOE VERA GEL1.0021DARNICA MONTANA FLOWER EXTRACT1.00ISI22DCHAMOMILA RECUTITA0.50(MATRICARIA) FLOWER EXTRACTACTIVE ORGANICS23DSODIUM HYALURONATE2.0024DETHYLHEXYL GLYCERIN1.0025EPOLYQUATERNIUM-372.0326E20% NAOH1.18

[0041]Phase “A” water is heated to 75° C. Natrasol, a thickening agent, is dispersed and is mixed with water for one hour. Remaining phase A ingredients are added. Phase B ingredients are c...

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Abstract

The invention is directed to a novel topical burn treatment compositions comprising a silicone containing compound, a Vitamin E compound and a local anesthetic. and their use in treating topical burns.

Description

PRIORITY CLAIM[0001]This application claims priority under 35 USC § 119(e) from application Ser. No. 60 / 891,158, filed Feb. 22, 2007 and application Ser. No. 60 / 947,478 filed Jul. 2, 2007, the contents of each (appln. Ser. Nos. 60 / 891,158 and 60 / 947,478) of which are incorporated by reference in their entireties.FIELD OF THE INVENTION[0002]The invention is directed to a novel topical burn treatment compositions and their use in treating topical burns. These compositions may comprise a silicone containing compound, a Vitamin E compound and a local anesthetic.BACKGROUND OF THE INVENTION[0003]Skin burns result in dyskeratotic cells, spongiosis, vacuolation of keratinocytes and edema from capillary leakage. As a consequence, skin burns may be very painful. Furthermore, blisters may develop and scabs and scars may result.[0004]One treatment that has been disclosed in U.S. Pat. No. 6,562,326 involves administering a composition comprising an anesthetic (e.g., tetracaine) and a surfactant ...

Claims

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Application Information

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IPC IPC(8): A61K31/355A61K36/886A61K36/28A61P17/02
CPCA61K9/0014A61K31/355A61K36/28A61K36/886A61K47/24A61K2300/00A61P17/02A61K36/00
Inventor FONTAINE, WANDAMADFES, DIANEPALEFSKY, IRWINWILSON, NI'KITA
Owner HEALING SKIN
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