Unlock instant, AI-driven research and patent intelligence for your innovation.

Composition for prevention of influenza viral infection comprising tannic acid, air filter comprising the same and air cleaning device comprising the filter

Inactive Publication Date: 2011-06-02
WOONGJIN COWAY
View PDF10 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In more serious cases, influenza causes complications which can be fatal.
Wild aquatic birds are the natural hosts for a large variety of influenza A. Occasionally, viruses are transmitted from one to another species and may then cause devastating outbreaks or give rise to influenza pandemics.
In addition, this subtype can infect pigs and birds.
Side effects associated with oseltamivir therapy include nausea and vomiting.
Zanamivir shows high antiviral effects, but poor bioavailability, with fast release from the kidney.
However, the spread of influenza results mostly from droplet infection such as by aerosol inhalation.
Influenza viruses may be inactivated by sunlight, disinfectants, surfactants, e.g., soap, which are however not effective for the removal of airborne viruses.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composition for prevention of influenza viral infection comprising tannic acid, air filter comprising the same and air cleaning device comprising the filter

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

Manufacture of an Air Filter Coated with Tannic Acid

[0069]Tannic acid (A&K Petrochem. Ontario. Canada) was added in an amount of 10 wt % to water to give a tannic acid solution. This solution was sprayed onto a polypropylene filter base which was then dried at 140° C. for 4 min.

experimental example 1

Assay for Inhibitory Activity of Tannic Acid Against Influenza Virus

[0070]Tannic acid was assayed for inhibitory activity against influenza virus as follows.

[0071]As influenza virus strains to be tested, influenza A subtype H1N1 viruses A / PR / 8 (H1N1) and A / WSN(H1N1) as well as the WHO standard strain influenza A (H1N1) (A / California / O4 / 09), which was responsible for the declaration of the 2009 pandemic, were used.

[0072]Tannic acid was used as a sample in the following procedure.

[0073]The MDCK (Mardine Darbine Canine Kidney) cell line was inoculated at a density of 1.5×106 cells / mL into 6-well plates which were then incubated at 37° C. for 24 hrs in a 5% CO2 atmosphere. Separately, tannic acid was diluted to 100 mg / ml (1×) in an injection solution. The dilution was subjected to serial 10-fold dilutions. The specimens thus obtained were added in an amount of 90 μL per well to 96-well plates. 10 uL of an influenza virus sample was added to each well, incubated for 10 min, and 10-fold d...

experimental example 2

Assay for Inhibitory Activity of the Air Filter Against Influenza Virus

[0076]The air filters coated with tannic acid, manufactured in Preparation Example 1, were assayed for inhibitory activity against the influenza virus as follows.

[0077]As influenza virus strains to be tested, influenza A subtype H1N1 viruses A / PR / 8 (H1N1) and A / WSN (H1N1) as well as the WHO standard strain influenza A (H1N1) (A / California / O4 / 09), which was responsible for the declaration of the 2009 pandemic were used.

[0078]The air filters manufactured in Preparation Example 1 were used as samples. For control, an air filter was not treated with tannic acid.

[0079]After being cut into a size of 2×2 cm, the filter was coated with a predetermined amount of the virus solution and incubated for 10 min so as to absorb the virus thereinto. A medium (1 mL) was loaded onto the filter which was then shaken for 10 min to wash off the virus. The filtrate was diluted to prepare specimens. 90 μL of each of the specimens was ad...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Volumeaaaaaaaaaa
Volumeaaaaaaaaaa
Volumeaaaaaaaaaa
Login to View More

Abstract

Disclosed are a composition for the prophylaxis of influenza viral infection comprising tannic acid, an air filter coated with the same, and an air cleaner comprising the air filter. Having high inhibitory activity against influenza virus, the composition comprising tannic acid can be applied to the prevention of influenza viral infection. Also, the filter coated with the composition can remove influenza virus from the air so that it can be employed in an air cleaner for the prophylaxis of influenza viral infection.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application claims the benefit under 35 U.S.C. §119(e) of U.S. Provisional Patent Application No. 61 / 252,327 filed Oct. 16, 2009, which application is incorporated herein by reference in its entirety.BACKGROUND OF THE INVENTION[0002]1. Field of the Invention[0003]The present invention relates to a composition for the prophylaxis of influenza viral infection, comprising tannic acid, an air filter comprising the same, and an air cleaner comprising the air filter.[0004]2. Description of the Related Art[0005]Influenza, commonly referred to as the flu, is an infectious disease caused by RNA viruses of the family Orthomyxoviridae. The most common symptoms of the disease are chills, fever, sore throat, muscle pains, a severe headache, coughing, weakness / fatigue and general discomfort. Fever and coughing are the most frequent symptoms. In more serious cases, influenza causes complications which can be fatal.[0006]Typically, influenza is trans...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/7032A61P31/16B05D1/28B05D1/18B05D1/02B05D3/00B05D7/02B05D7/24B01D39/00
CPCA61K31/7024A61K31/7032B01D2239/0471B01D46/0028B01D2239/0442A62B18/00A61P31/16
Inventor KIM, HYOUNG JOONPARK, CHAN JUNG
Owner WOONGJIN COWAY
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com