Use of pharmaceutical compositions in preparing pharmaceuticals for treating diabetic ulcer

Abstract

The use of pharmaceutical compositions in preparing pharmaceuticals for treating diabetic ulcer in limb or on body surface, or in preparing medical dressing. The pharmaceutical compositions consist of (A) 3 to 15% by weight of edible beeswax and (B) 85 to 97% by weight of sesame oil extract of Scutellaria root, Coptis root, Phellodendron bark, earthworm and poppy capsule, based on the total weight of the pharmaceutical compositions. In the sesame oil extract, each of Scutellaria root, Coptis root, Phellodendron bark, earthworm and poppy capsule is in an amount of 2 to 10% by weight of dry raw material based on the total weight of sesame oil. A medical dressing for treating diabetic ulcer and corresponding medicine box enclosing the said dressing are also provided.

Description

FIELD OF THE INVENTION[0001]This invention relates to use of pharmaceutical compositions in preparing pharmaceuticals for treating diabetic ulcer in limb or on body surface, or in preparing medical dressing. This invention also relates to a kind of medical dressing for treating diabetic ulcer in limb or on body surface, and the corresponding medicine box enclosing the said dressing.BACKGROUND OF THE INVENTION[0002]Chinese Patent ZL931002761 has disclosed a pharmaceutical composition for treating thermal injuries; the said pharmaceutical composition consists of (A) 3 to 15% of edible beeswax and (B) 85 to 97% of sesame oil extract of Huangqin, Huanglian, Huangbai, earthworm and poppy capsule, based on the total weight of the pharmaceutical composition. In the sesame oil extract, each of Huangqin, Huanglian, Huangbai, earthworm and poppy capsule is in an amount of 2 to 10% by weight of dry raw material based on the total weight of sesame oil.[0003]Furthermore, the pharmaceutical compo...

AI Technical Summary

Problems solved by technology

Although the definition of ulcer seems self-evident, many professionals are not very familiar with the difference between wound and ulcer.

So far, there are still no ideal and effective pharmaceuticals for diabetic ulcer world wide.

The pathogenetic mechanism of diabetic ulcer is very complicated, and there is no unified and common clear understanding for the time being.

These pathological changes result in ischemia of soft tissue in leg and on body surface, and finally evolve into ulcer.

During this pathogenesis, all the neural functions are damaged, but often, the longest and the thinnest nervous fiber, including the motor nerve that controls the foot muscles, is damaged first.

Functional loss of lumbrical muscle leads to foot deformation, and this increases the pressure or friction in the sites of sub-metatarsophalangeal joint, toe dorsum or toe tips and the like.

These factors easily induce ulcers.

Damage to autonomic nerve function also emerges in the earlier stage of neuropathy, causing a series of pathological changes, including arteriovenous shunt, decreased tissue infusion, alopecia, functional loss of sebaceous glands and sweat glands.

These elements work together and result in skin dryness, scale formation and liab

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