Sweat simulation collection and sensing systems
a technology of sensing system and sweat, applied in the field of sweat simulation collection and sensing system, can solve the problems of high contamination risk, high cost, invasiveness, etc., and achieve the effect of providing
Pending Publication Date: 2020-05-21
UNIVERSITY OF CINCINNATI
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Benefits of technology
Provides a reliable, non-invasive means to monitor biomarker concentrations over time, allowing for the detection of health indicators like cardiac stress, stroke diagnosis, and hydration status without the need for blood draws, with data transmission via wearable devices.
Problems solved by technology
Other test fluids have also considered for determining biomarkers in blood, for example, saliva, urine and breath have all been considered but are awkward and highly prone to contamination.
Utilizing implantable sensors to analyze blood is expensive and invasive and presents significant risks.
Method used
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Embodiment Construction
[0019]According to the present invention sweat is used to determine concentrations or meaning of biomarkers in blood in a non-invasive manner As shown in FIG. 1, a sweat collector 10 that permits chronological sweat storage of a plurality of samples includes a central sweat collection member 12 having a sweat collecting central base 14 leading to a central fluid transporting core 16 leading to a plurality of arms 18. Core 16 further leads to a top portion 20 (only shown in FIG. 2) which allows for evaporation or storage of the sweat which therefore provides for continued fluid flow.
[0020]The sweat collector member 12 can be formed from any material which will readily transport sweat. Generally, a fibrous web, such as a cellulosic web, is particularly suitable for use in this application. It can be treated with a hydrophilic substance which will promote fluid flow. However, any material which will readily allow aqueous fluid flow can be used as the sweat collection member.
[0021]Sweat...
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Abstract
Biological chemicals, potentially found in blood are measured by collecting sweat and determining the concentration or meaning of the selected chemical in sweat. The sweat can be collected using a time based, interval collector 10 and analyzed using an external device. It can also be collected on a one time basis, using a flexible, chemical capacitor 50, or on a continuous basis using a chemical, field effect transducer 98.
Description
RELATED APPLICATION[0001]The present application claims priority to U.S. Ser. No. 61 / 620,069 filed Apr. 4, 2012, the disclosure of which is hereby incorporated herein by reference in its entirety. The present application further claims priority to International Application No. PCT / US13 / 35092 filed Apr. 3, 2013, and International Application Publication No. WO 2013 / 152087 published Oct. 10, 2013, the disclosures of which are hereby incorporated herein by reference in their entireties. The present application further claims priority to U.S. Ser. No. 14 / 388,416 filed Sep. 26, 2014, and U.S. Application Publication No. US 2015 / 0057515 published Feb. 26, 2015, the disclosures of which are hereby incorporated herein by reference in their entireties.STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT[0002]The invention was made with government support under SAPGrant No. 1008512 awarded by U.S. Air Force Research Labs. The government has certain rights in the invention.BACKGROUN...
Claims
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IPC IPC(8): G01N27/327G01N27/414A61B5/145B01L3/00A61B5/1477A61B10/00A61B5/00
CPCA61B5/1477A61B5/0002A61B5/14546B01L3/5023B01L2400/086A61B10/0096G01N27/4145A61B5/681B01L2300/0645A61B5/14517B01L2300/069B01L2300/0864B01L2200/0621B01L2300/0803B01L2300/023G01N27/3273B01L2300/022A61B10/0064B01L2400/0677A61B5/14532B01L2400/0406G01N1/10G01N33/487G01N33/50B01L2300/0636B01L2300/163
Inventor HAGEN, JOSHUA A.HEIKENFELD, JASON C.PAPAUTSKY, IANHOU, LINLINNAIK, RAJESHKELLEY - LOUGHNANE, NANCYSTONE, MORLEYBUSBEE, JOHNWANG, XIAO
Owner UNIVERSITY OF CINCINNATI