Luminal stent, holding structure therefor and device for attaching luminal stent

a technology of luminal stents and stents, which is applied in the field of stent introduction, can solve the problems of abnormal multiplication of living cells on the inner wall of the vessel to contract the vessel, high risk, and stenosis at the site of stent attachment,

Inactive Publication Date: 2005-03-15
IGAKI IRYO SEKKEI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This known type of the stent however suffers from the problems that it is hard and tends to stress the vessel to produce inflammation of hypertrophy in the vessel which may cause reconstriction in the vessel, and that the stent is semipermanently left as a foreign matter within the living body, which is inherently not desirable to the living body.
If the metal stent, which is left in the vessel semi

Method used

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  • Luminal stent, holding structure therefor and device for attaching luminal stent
  • Luminal stent, holding structure therefor and device for attaching luminal stent
  • Luminal stent, holding structure therefor and device for attaching luminal stent

Examples

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Effect test

experiment 1

Plural luminal stents formed by knitting a yarn of polylactic acid fibers admixed with barium sulfate were introduced and attached in the coronary of a test animal in a tubular state of 4 mm in diameter and 20 mm in length by using a catheter fitted with a balloon, and the state of attachment was observed by irradiation of X-rays. It was seen that the stents substantially maintained their shape until after about three to six months. It was seen that the stents disappeared by being absorbed into living tissue in about 6 to 12 months. During this time, no abnormalities such as inflammation or hypertrophy of the intima of the blood vessel were observed.

experiment 2

Plural luminal stents formed by knitting a yarn of polyglycolic acid fibers admixed with barium sulfate were introduced and attached in the femoral artery of a test animal in a tubular state of 4 mm in diameter and 20 mm din length and the state of attachment was observed by irradiation of X-rays. It was seen that the stents substantially maintained their shape until after about two to three weeks and were absorbed into the living tissue in about two to three months. The shape retention period and the period of existence in the living body attained in Experiment 2 are thought to be more safe than the corresponding periods attained in Experiment 1. Meanwhile, no inflammation or hypertrophy of the intima of the blood vessel was observed during these periods.

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Abstract

A luminal stent is a tubular body formed by knitting a sole yarn of a bioresorbable polymer fiber, such as fiber of polylactic acid, polyglycol acid or a polylactic acid—polyglycol acid copolymer. When introduced into and attached to the inside of the vessel by a catheter fitted with a balloon, the tubular member may retain its shape for several weeks to several months after attachment and subsequently disappears by being absorbed into the living tissue. In this manner, the luminal stent is not left as a foreign matter semi-permanently in the living body without producing inflammation or hypertrophy in the vessel. There is also provided a method for attaching the luminal stent in the vessel.

Description

TECHNICAL FIELDThis invention relates to a stent introduced into a vessel, such as a blood vessel, lymph vessel, bile duct or ureter for maintaining the shape of the vessel. More particularly, it relates to a luminal stent attached to a site of angioplasty after the operation of percutaneous angioplasty of a stenotic part of the blood vessel, such as artery (the operation of introducing a balloon forming portion annexed to the end of a catheter into a constricted portion of the blood vessel for forming a ballooning for dilating the constricted portion for improving blood flow) and a device for attaching the luminal stent.BACKGROUND TECHNOLOGYAs this type of the luminal stent, there is known a tubular stent constituted by wrapping a meshed structure formed by intertwining longitudinal and transverse wires of e.g. stainless steel. Such tubular stent is introduced into the site of angioplasty and dilated there so as to be attached thereto.This known type of the stent however suffers fr...

Claims

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Application Information

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IPC IPC(8): A61F2/06A61L31/04A61L31/06A61F2/02A61F2/90
CPCA61F2/90A61F2/958A61L31/06C08L67/04A61F2210/0004A61F2220/0008
Inventor IGAKI, KEIJITAMAI, HIDEO
Owner IGAKI IRYO SEKKEI
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