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6 results about "Bones growth" patented technology

Osteoblasts, osteocytes and osteoclasts are the three cell types involved in the development, growth and remodeling of bones. Osteoblasts are bone-forming cells, osteocytes are mature bone cells and osteoclasts break down and reabsorb bone.

Perfusate suspension device with dual-redundancy pressure protection

The invention discloses a perfusate suspension device with dual-redundancy pressure protection, relates to the technical field of lavage after tibial osteomyelitis in the children orthopedics department, and aims to solve the problem that an existing perfusate suspension device is difficult to operate in lavage after tibial osteomyelitis in children. The technical problems that in the prior art, a dynamic pressure protection mechanism matched with child bone growth is lacked, interference of temperature on pressure monitoring is not eliminated, redundant protection is not achieved, and bone wall damage or incomplete lavage is likely to happen are solved, and the device comprises a hanging assembly used for bearing a perfusate container; the perfusion assembly comprises a perfusion pipeline and a lavage needle, and the two ends of the perfusion pipeline are connected with an outlet of the perfusate container and the lavage needle respectively; and the dual-redundancy pressure monitoring module comprises two independent pressure acquisition paths which are used for respectively acquiring the pressure in the marrow cavity and the pressure in the perfusion pipeline, and the two acquisition paths are synchronously connected to the temperature compensation unit. The device has the advantages that accurate pressure monitoring and dynamic threshold adjustment are achieved, and the child lavage safety and effect are guaranteed.
Owner:JIAXING CITY NO 2 HOSPITAL

A perspective image analysis method for bionic repair of bone tumor

The application discloses a perspective image analysis method for bionic repair of bone tumors, comprising the following steps: acquiring perspective image data of a bone tumor area; performing cross-modal feature alignment on the data, constructing a three-dimensional bone tumor image model in a three-dimensional voxel space coordinate system, and eliminating image artifacts; performing segmentation processing on the bone tumor through a deep learning segmentation network, identifying a bone tumor infiltration boundary, and acquiring three-dimensional morphological parameters and bone tumor characteristic parameters of the bone tumor area; reconstructing a bionic scaffold structure of a bone defect area through biomechanical modeling, and implanting the bionic scaffold into the bone tumor area; and acquiring bone-scaffold interface fusion rate, stress distribution uniformity and new bone growth depth indexes based on postoperative image data. The application has the advantages that: through the combination of accurate segmentation at the voxel level and a convolutional neural network, the bone tumor area and morphology can be accurately identified and divided, thereby providing reliable support for subsequent tumor infiltration evaluation and bionic scaffold design.
Owner:WUHAN CHINESE & WESTERN MEDICINE UNION HOSPITAL

A bone promoting antibacterial biological functional material and a preparation method thereof

The present application relates to a kind of promote bone antibacterial biological function material and its preparation method, belong to laser application technical field.The present application is after polishing nickel-titanium alloy material ultrasonic and dry, using femtosecond laser direct writing technology, through the laser flux of synergic control processing process, processing translation table moving speed and scanning pitch and other processing parameters, prepare the self-organizing composite periodic micro-wave groove structure;It is again after being handled by anodic oxidation, form rich nanometer hole on the basis of the structure, prepare to get groove-micro-wave groove-micropore three-level micro-nano composite structure;Subsequently, the three-level micro-nano composite structure prepared is placed in the alkaline Tris buffer solution containing hydrochloric acid dopamine, and the polydopamine coating is attached;Subsequently, the groove-micro-wave groove-micropore three-level micro-nano composite structure with polydopamine coating is placed in silver nitrate solution, to load nano-silver on its surface, finally, the biological function material with good bone bonding ability, promote bone growth ability and antibacterial ability is prepared.
Owner:BEIJING INST OF TECH

System and method for altering growth of bones

ActiveUS12558127B2Internal osteosythesisFastenersRotational deformityGonial angle
The present inventions relate to a system and method for altering growth of bones. More precisely, the system is an orthopedic apparatus for correcting rotational deformities and limb length discrepancies. A system of cable-couplings with linking members is used, the linking members being posts or screws traversing bones. Due to the flexibility and adaptability of the system and its components, the cable-coupling members may be installed at varying angles and locations while allowing for growth arrest or rotational corrections of said bones. A method to limit growth using cable-couplings systems is also provided.
Owner:ORTHOPEDIATRICS CANADA ULC

A bone repair material using cervus flacca polypeptide and a preparation method thereof

PendingCN122297785AOsteoblastBiocompatibility
This invention relates to the field of bone repair materials technology, and discloses a bone repair material utilizing deer bone peptides and its preparation method. The method includes the preparation of deer bone extract, the preparation of melon seed extract, the formulation of a composite peptide solution, the preparation of a carrier base solution, and the compounding and molding. By using a composite peptide solution containing deer bone peptides and melon seed peptides, the synergistic effect of the two peptides enables the material to possess excellent osteoblast proliferation, differentiation, and anti-inflammatory activity, thereby promoting the repair and regeneration of bone defects and enhancing the bioactivity and therapeutic targeting of the material. By mixing the composite peptide solution with a carrier base solution containing a biocompatible carrier material and adding a cross-linking agent for cross-linking, a stable structure is formed between the peptides and the carrier material, thereby ensuring that the material has good mechanical support properties and a controllable degradation rate, ensuring that the material maintains its morphology in the early stages of implantation and guides new bone growth in an orderly manner over time.
Owner:HEILONGJIANG DILONG PHARM CO LTD

Use of mulberry total polyphenol extract in preparation of product for promoting bone formation

PCT designated stageWO2026148690A1OsteoblastIsoflavones
Provided is the use of a mulberry total polyphenol extract in the preparation of a product for promoting bone formation. The active ingredients of the mulberry total polyphenol extract include phenolic acids, polyphenol derivatives, flavones, isoflavones and tannins. The product for promoting bone formation can promote osteoblast proliferation, promote osteogenic calcification, inhibit sclerostin activity, and / or promote bone growth.
Owner:QINGDAO UNIV +1