Artificial blood vessel blended by utilizing natural bent synthetic fibre and protein fibre and its production method

Abstract

The present invention relates to artificial organ, in particular it relates to a natural flexible synthetic fibre and protein fibre blended artificial blood vessel with good biological modification potential energy. The natural flexible synthetic fibre is the fibre made up by using two polyester chip with different contraction rates through the processes of mixing, melting and spinning and having cyclic tortuous property, so that it has natural flexible property. The production process of said invented artificial blood vessel made up by blending the above-mentioned natural flexible synthetic fibre and protein fibre is similar to that of other general artificial blood vessel, but said invented artificial blood vessel has higher strength, good vessel wall permeability and good tissue compatibility.

Description

technical field [0001] The invention relates to an artificial organ, in particular to a natural curved synthetic fiber and protein fiber blended artificial blood vessel with good biomodification potential. Background technique [0002] Currently clinically used artificial blood vessels are mainly made of synthetic fibers, including polyester fibers and modified polytetrafluoroethylene fibers. One of their common features is that the permeability between fibers allows human cells to grow in; the other is the tissue compatibility guaranteed by stable chemical properties. [0003] The development direction of artificial blood vessels is to undergo biochemical modification, mainly including planting endothelial cells or endothelial cell growth factors, and grafting anticoagulant and antithrombotic drugs to make artificial blood vessels have better blood compatibility. But precisely because of the extremely stable chemical properties of synthetic fibers, it is usually difficult ...

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Problems solved by technology

[0004] There are usually three improved methods: first, to make blood vessels from protein fibers alone, but the strength of these fibers is not ideal at present, and it is not yet possible to make blood vessels alone; second, to interweave synthetic fibers and protein fibers to form blood vessels, but After biochemical treatment of such blood vessels, it cannot be ruled out that part of the inner wall of the blood vessel has biological properties, while the other part does not have biological properties; third, synthetic fibers and protein fibers are blended into yarns and then woven into blood vessels The method is limited by the inflexibility of the synthetic fiber itself, so that it cannot be entangled with other fibers into a yarn by twisting

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