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A medicine composition for treating hyperuricemia

A technology of hyperuricemia and composition, applied in the field of pharmaceutical composition for treating hyperuricemia

Active Publication Date: 2009-03-04
中山市恒生药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these drugs often have many diseases such as liver dysfunction, aplastic anemia, granulocytopenia, Smith-Johnson syndrome, neutrophil necrosis, allergic vasculitis, acute renal failure, interstitial pneumonia, rhabdomyolysis, etc. side effects, so it has become a development trend to find safe and effective traditional Chinese medicine preparations and other natural medicines

Method used

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  • A medicine composition for treating hyperuricemia
  • A medicine composition for treating hyperuricemia
  • A medicine composition for treating hyperuricemia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Composition: Astragalus extract 165g (astragalus total saponin content 10%, astragaloside IV content ≥ 0.20%, hereinafter the same),

[0018] Cortex chinensis extract (total coumarin content of bark bark ≥ 50%, esculin content ≥ 5%, the same below) 66g,

[0019] Tea extract (tea polyphenol content ≥ 50%) 20g,

[0020] Appropriate amount of excipients for conventional tablet preparations.

[0021] The above raw materials were mixed and granulated according to the conventional manufacturing process of oral tablets, and compressed into tablets to obtain 1000 tablets for oral administration.

Embodiment 2

[0023] Composition: Astragalus Extract 130g

[0024] Qin Bark Extract 66g

[0025] Tea Extract 15g

[0026] Appropriate amount of excipients for capsule preparation

[0027] The above raw materials are mixed and granulated according to the manufacturing process of conventional oral capsule medicine, and then packed into capsules to obtain 1000 capsules for oral administration.

Embodiment 3

[0029] Composition: Astragalus Extract 150g

[0030] Qin Bark Extract 66g

[0031] Tea Extract 10g

[0032] Appropriate amount of excipients for conventional oral liquid

[0033] Dissolve the above raw materials in distilled water, mix evenly according to the conventional oral liquid preparation manufacturing process, add flavoring agents, stabilizers, etc., and fill to obtain 1000 oral liquids.

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Abstract

The medicine composition for treating hyperuricemia consists of basic effective medicine components including astragalus root extract in 1-8 weight portions, cortex fraxini extract in 0.3-3 weight portions and tea extract in 0.1-2 weight portions, and pharmaceutically acceptable supplementary material. Of the basic effective medicine components, the astragalus root extract contains total astragaloside not less than 10 %, the cortex fraxini extract contains total cortex fraxini coumarin not less than 30 %,and the tea extract contains tea polyphenol not less than 50 %. The medicine composition may be prepared into common oral preparation or injection for controlling the acute attack of gouty arthritis, treating hyperuricemia and chronic uric acid type nephropathy, remitting arthralgia and promoting uric acid excretion.

Description

technical field [0001] The invention relates to a pharmaceutical composition which can be used for treating various diseases caused by hyperuricemia. Background technique [0002] Gout is a disease caused by purine metabolism disorder. The clinical features are hyperuricemia and the resulting gouty arthritis, chronic uric acid nephropathy, and kidney stones. In traditional Chinese medicine, it belongs to the category of arthralgia. At present, it is believed that the main causes of increased blood uric acid are: (1) increased production of uric acid in the body; (2) renal insufficiency, decreased renal excretion of uric acid; (3) both increased production and decreased excretion. At present, gout and hyperuricemia have become common diseases in middle-aged and elderly people. Especially with the continuous improvement of living standards, the number of clinical patients has also increased sharply. The current treatment of such diseases mainly adopts chemical drugs such as...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/82A61K9/16A61K9/20A61K9/48A61K9/08A61P19/06
Inventor 赖智填陈幸
Owner 中山市恒生药业有限公司
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