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Gene detecting probe information annotate method

A gene probe and probe technology, applied in the field of gene chip technology platform construction, can solve problems such as inability to annotate information, difficult data warehouse management, limited annotation capabilities of DRAGON system, etc., and achieve the effect of increasing the number and data update time

Inactive Publication Date: 2007-10-31
SHANGHAI INST OF BIOLOGICAL SCI CHINESE ACAD OF SCI
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Problems solved by technology

[0004] However, this technology has great limitations: the biggest limitation of the data warehouse is that the technology cannot be updated in real time
[0005] Another limitation of the data warehouse annotation method is that due to the inconsistency of the data format of the public source database, as the number of source databases and data types increases, the data warehouse management will become more and more difficult. Therefore, the annotation of the data warehouse method limited ability
Taking the aforementioned another probe annotation system DRAGON system as an example, due to the limited annotation capabilities of the DRAGON system, it cannot annotate the information of the most commonly used databases GenBank and LocusLink

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Embodiment Construction

[0019] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0020] Fig. 1 shows the flow of the gene probe information annotation method of the present invention, and Fig. 2 shows the data flow of the gene probe information annotation method of the present invention. Please refer to Fig. 1 and Fig. 2 at the same time, the following is a detailed description of the method steps.

[0021] Step S11: Input the identification number (ID) for preparing the gene chip probe library. The information of gene chip probes usually uses its accession number (Accession Number) as the unique identifiable ID. At the same time, UniGeneCluster ID (hereinafter referred to as UniGene ID) and LocusLink ID (ie, the Gene ID of the Entrez Gene database) are important in the chip information. It appears frequently due to its uniqueness, and can also be entered as the initial unique ID. The input format of the gene chip probe ID can be ...

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Abstract

This invention discloses one gene detector information note method, which combines linkage technique and database warehouse technique and comprises the following steps: a, inputting label information in the gene chip detector database into data warehouse system; b, extracting gene detector label information and public source database label information relationship; c, according to the linkage between database and through linkage extracting detail information relative to public source database and gene chip detector; d, analyzing detail information for output.

Description

technical field [0001] The invention relates to a construction method of a gene chip technology platform, in particular to an information annotation method of a gene chip probe. Background technique [0002] The emergence of gene chips is a major development with great characteristics of the times in the field of high-tech in recent years. It is a high-tech formed by the comprehensive intersection of physics, microelectronics and molecular biology. Gene chip technology is a high-throughput technology. Its basic principle is to integrate tens of thousands of DNA probes on a centimeter-square chip through micro-processing technology to achieve efficient and rapid quantitative detection of mRNA and DNA sequences. In application fields such as the elaboration of gene functions, the exploration of disease causes and mechanisms, the discovery of possible diagnostic and therapeutic targets, gene chips are being used more and more. [0003] Due to the high-throughput and high-infor...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/00G06F17/30
Inventor 金刚谢松旻王超
Owner SHANGHAI INST OF BIOLOGICAL SCI CHINESE ACAD OF SCI