Azelnidipine medicinal composition and its preparing method

A technology of azelnidipine and its composition, which is applied in the field of pharmaceutical compositions containing azelnidipine, and can solve problems such as the decrease of dissolution rate
CN101103979BInactive Publication Date: 2010-12-08BEIJING SIHUAN KEBAO PHARM CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BEIJING SIHUAN KEBAO PHARM CO LTD
Publication Date
2010-12-08
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a compound for treating hypertensive, particularly relating to a calcium ion antagonist drug complex with full dissolution, good stability and high bioavailability. The invention is characterized in that the complex contains (A) calcium channel antagonist, (B) alkaline excipient with effective dose and (C) non-ionic surfactant; wherein (A):(B):(C) is ranged from 0.1:1:1 to 10:1:1.
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Description

technical field

[0001] The present invention relates to a pharmaceutical composition containing azendipine, which can be used in the treatment of hypertension. In particular, the present invention relates to an azeldipine pharmaceutical composition with complete dissolution, good stability and high bioavailability. Background technique

[0002] At present, hypertension has become the main killer that endangers human health, and patients with hypertension account for about 50% of cardiovascular cases. According to statistics from the National Ministry of Health, there are 130 million hypertensive patients in my country, and the incidence rate increases by 25% every 10 years, with an annual increase of more than 3 million people. Azedipine is a new generation of L-type calcium channel selective antagonist. This product has clinical advantages such as good antihypertensive effect, does not affect heart rate, can improve renal function, and has few side effects. Therefore, pro...

Claims

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