Diacetyl morphine quick-speed testing apparatus

A detection device and heroin technology are applied in the field of devices for rapid detection of heroin in human body fluids, which can solve the problems of low accuracy, false positives, and low heroin accuracy, and achieve the effect of easy determination.

Inactive Publication Date: 2008-03-05
王志洪 +1
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AI Technical Summary

Problems solved by technology

When people inhale prescription analgesics such as codeine (Codeine, structural formula is E), morphine will also be produced in body fluids; on the other hand, many prescription analgesics contain substances similar to morphine ( Such as Hydrocodone, the structural formula is F; Hydromorphone, the structural formula is G; Oxymorphone, the structural formula is H; Oxycodone, the structural formula is I), even if these items do not produce morphine during human metabolism, false positive results will also be produced, that is, when the human body fluid is stored When there are such groups, the morphine reagent will also be positive. Therefore, there are technically insurmountable defects in the detection of heroin with existing products.
According to the U.S. "JOURNAL OFANALYTICAL TOXICOLOGY" VOL30, March 2006, pages 73-79, 3521 urine sa

Method used

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  • Diacetyl morphine quick-speed testing apparatus
  • Diacetyl morphine quick-speed testing apparatus
  • Diacetyl morphine quick-speed testing apparatus

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Example Embodiment

[0028] Embodiment 1: the heroin rapid detection device of the present invention, comprises carrier 1, sampling pad 2, reaction block 3, coated diaphragm 4 and absorbent paper 5, wherein sampling pad 2, reaction block 3, coated diaphragm 4 and Absorbent papers 5 are pasted on the carrier 1 successively by overlapping each other. The reaction block 3 contains an antigen for the heroin-specific metabolite 6-acetylmorphine. The control area 7 contains the antibody against the heroin-specific metabolite 6-acetylmorphine in the detection area 6, and the antigen for the heroin-specific metabolite 6-acetylmorphine is labeled with colloidal gold in the reaction block 3. The antigen structure of heroin specific metabolite 6-acetyl morphine has structural formula B or structural formula C two kinds, wherein structural formula B is connected with macromolecule (bovine serum albumin) through six positions of 6-acetyl morphine, and structural formula C is Linkage to macromolecules (bovine s...

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Abstract

The invention comprises: carrier, sampling pad, reaction block, peridium film and absorbent paper. Said sampling pad, reaction block, peridium film and absorbent paper are sequentially pasted on the carrier; said reaction block containing the antigen and antibody to the 6-acetyl morphin which is a specificity metabolite of heroin; the antigen to the 6-acetyl morphin has B,C two structures; the B is 6 bits and is connected to the bovine serum albumin; the C is connected to the bovine serum albumin through N base group.

Description

technical field [0001] The invention relates to a device for rapidly detecting heroin in human body fluid. Background technique [0002] Heroin is a world-recognized drug, which is extremely harmful to human beings. Heroin smoking is one of the daily targets of the public security traffic police in our country. The detection and analysis method is used to judge, not only the detection time is long, the detection is very inconvenient, and the work efficiency is extremely low, but also the traditional gas phase or liquid chromatography can not implement rapid detection and discrimination on the spot. In the patent 200510038688. and drug devices, which are based on morphine-specific antigens or antibodies. Although some drug addicts can be detected with this product, there are both a high proportion of false positives and a certain proportion of drug users in the test results. False negatives, this problem has plagued the daily law enforcement of law enforcement officers. The...

Claims

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Application Information

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IPC IPC(8): G01N33/549
Inventor 王志洪王国洪
Owner 王志洪
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