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Compound medicaments treating gastritis, gastric ulcer, and duodenal ulcer and preparation thereof

A compound and co-precipitation technology, which is applied in the direction of drug combinations, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem of single therapeutic effect, achieve pain relief, increase pH value, and promote Effects of mucosal cell metabolism

Inactive Publication Date: 2008-09-10
重庆北碚现代应用药物研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, although there are many types of drugs for treating gastritis, gastric ulcer and duodenal ulcer at home and abroad, a considerable part of the drugs, such as antacids, can only stop acid, relieve pain and relieve symptoms; promote the healing of gastrointestinal ulcers. Antispasmodic drugs only protect and repair gastrointestinal damage; gastrointestinal antispasmodic drugs only relieve pain caused by spasms and relieve symptoms, and their therapeutic effects are relatively single

Method used

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  • Compound medicaments treating gastritis, gastric ulcer, and duodenal ulcer and preparation thereof
  • Compound medicaments treating gastritis, gastric ulcer, and duodenal ulcer and preparation thereof
  • Compound medicaments treating gastritis, gastric ulcer, and duodenal ulcer and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The preparation formula 1 of embodiment 1 compound glutamine tablet

[0030]

[0031] Glutamine 300g

[0032] Co-precipitate of aluminum hydroxide and sodium bicarbonate 100g

[0033] Phenidaethanol Hydrochloride 1.5g

[0034] Starch 20g

[0035] Lactose 10g

[0036] Microcrystalline Cellulose 7g

[0037] Carboxymethyl Starch Sodium 10g

[0038] Magnesium Stearate 2g

[0039] 60% ethanol 10g

[0040]

[0041] Makes 1000 pieces

Embodiment 2

[0042] The preparation formula 2 of embodiment 2 compound glutamine tablet

[0043]

[0044] Glutamine 200g

[0045] Co-precipitate of aluminum hydroxide and sodium bicarbonate 67g

[0046] Diphenhydramine Hydrochloride 1g

[0047] Povidone K30 15g

[0048] Microcrystalline Cellulose 5g

[0049] Carboxymethyl Starch Sodium 5g

[0050] Magnesium Stearate 1g

[0051] 60% ethanol 8g

[0052]

[0053] Makes 1000 pieces

Embodiment 3

[0054] The preparation formula of embodiment 3 compound glutamine capsules

[0055]

[0056] Glutamine 200g

[0057] Co-precipitate of aluminum hydroxide and sodium bicarbonate 67g

[0058]Diphenhydramine Hydrochloride 1g

[0059] Microcrystalline Cellulose 5g

[0060] 60% ethanol 8g

[0061]

[0062] Makes 1000 capsules

[0063] The following test examples have further demonstrated the beneficial effects of the present invention

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Abstract

The present invention provides a compound tablet or capsule for remedying the gastritis, the gastric ulcer and the duodenum ulcer, which mainly contains glutamine, the coprecipitator of aluminium hydroxide and sodium bicarbonate, ethanol piperidine hydrochloride and medical accessory materials. The mix radio by weight of each component are 200 to 300 portions of the glutamine, 60 to 100 portions of the coprecipitator of aluminium hydroxide and the sodium bicarbonate, 1 to 1.5 portions of the ethanol piperidine hydrochloride, 0 to 30 portions of filling agent, 1 to 10 portions of wetting agent, 0 to 10 portions of bond, 0 to 10 portions of disintegrant and 0 to 2 portions of lubricant. The prevent invention makes up the disadvantage of the single therapeutic action of the prior medicine for remedying the gastritis, the gastric ulcer and the duodenum ulcer and provides a compound medicine which has more comprehensive therapeutic actions of relieving hyperacidity, spasmolysis and restoring damaged gastrointestinal mucosal for the gastritis, the gastric ulcer and the duodenum ulcer. At the same time, the present invention provides the preparation method of a compound glutamine tablet and capsule.

Description

technical field [0001] The invention belongs to a medical compound preparation containing organic active ingredients, in particular to a compound glutamine tablet or capsule for treating gastritis, gastric ulcer and duodenal ulcer and a preparation method thereof. Background technique [0002] At present, although there are many types of drugs for treating gastritis, gastric ulcer and duodenal ulcer at home and abroad, a considerable part of the drugs, such as antacids, can only stop acid, relieve pain and relieve symptoms; promote the healing of gastrointestinal ulcers. Antispasmodic drugs only protect and repair the damage of gastrointestinal tract; gastrointestinal antispasmodic drugs only relieve the pain caused by spasm and relieve symptoms, and the therapeutic effect is relatively single. Contents of the invention [0003] The purpose of the present invention is to overcome the shortcomings of the above-mentioned prior art and provide a compound glutamine tablet or c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61K33/00A61K9/28A61K9/48A61K47/38A61P1/04A61K31/4458A61K31/198
Inventor 王兰周
Owner 重庆北碚现代应用药物研究所
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