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A technology of psyllium polysaccharide and oral preparation, applied in the field of traditional Chinese medicine preparations, can solve the problems that experimental research has not yet been reported and the like
Inactive Publication Date: 2008-09-24
HEBEI MEDICAL UNIVERSITY
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Problems solved by technology
At present, although there are many reports on the impact of plantago seed on animal pharmacodynamics, there is no report on the experimental research of plantago seed polysaccharide on animal in vitro models.
Method used
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Embodiment 1
[0037] Embodiment 1 Granules
[0038] Component Weight %
[0039] Psyllium polysaccharide 5
[0040] Starch 50
[0041] Dextrin 40
[0042] Crospovidone 5
[0043] Specific operation process: mix the psyllium seed polysaccharide in the above ratio with starch, dextrin, and crospovidone evenly, add 5% starch slurry in an appropriate amount to make a soft material, use a granulator to granulate, dry, and granulate. Granules.
Embodiment 2
[0044] Embodiment 2 Granules
[0045] Component Weight %
[0046] Psyllium polysaccharide 50
[0047] Lactose 45
[0048] Crospovidone 5
[0049] Specific operation process: Mix the plantaginacea polysaccharide, lactose, and cross-linked povidone in the above ratio evenly, add 3% povidone solution in an appropriate amount to make a soft material, use a granulator to granulate, dry, and granulate to obtain granules agent.
Embodiment 3
[0050] Embodiment 3 granules
[0051] Component Weight %
[0052] Psyllium polysaccharide 80
[0053] starch 17
[0054] Crospovidone 3
[0055] Specific operation process: mix the psyllium seed polysaccharide of the above formula with starch and cross-linked povidone evenly, add an appropriate amount of 3% povidone solution to make a soft material, use a granulator to granulate, dry, and granulate. Granules.
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Abstract
The invention provides a semen plantaginis polysaccharide oral pharmaceutical preparation, preparation method and application. The oral pharmaceutical preparation is prepared through the following steps, that is, microwave extraction, concentration, precipitation separation and pharmaceutical preparation. The oral pharmaceutical preparation can be made into granules, tablets, pillers or oral liquids according to a weight percentage of 5 to 80 percent of semen plantaginis polysaccharide and the rest of other pharmaceutical adjuvants. A preliminary research proves that semen plantaginis can play an obvious role in resisting oxidation and clearing freeradicals, block the generation of oxLDL and relax blood vessels and protect the artery endothelium by releasing nitric oxide (NO). The semen plantaginis polysaccharide oral pharmaceutical preparation is expected to be developed to be a new pharmaceutical preparation product capable of resisting oxidation, clearing freeradicals and preventing and curing atherosclerosis.
Description
technical field [0001] The invention relates to an oral preparation, preparation method and application of psyllium seed polysaccharide, especially as an application for preparing anti-oxidation free radical scavenging medicine, which belongs to the technical field of traditional Chinese medicine preparations. Background technique [0002] Plantago is the dry and mature seed of Plantaginaceae Plantaginaceae, which is widely distributed in my country and rich in resources, and is one of the traditional Chinese medicines in my country. It has the functions of clearing heat and diuresis, eliminating dampness and treating stranguria, improving eyesight and eliminating phlegm. Foreign studies of psyllium seed have shown that the seed coat of psyllium seed contains a large amount of mucilage, which is a heteropolysaccharide composed of xylose, arabinose, rhamnose, galactose, glucose, galacturonic acid, etc. The polysaccharide is a kind of Partially fermentable dietary fiber not o...
Claims
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Application Information
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