Method for detecting quality of niaolukang particles

Abstract

The invention discloses a method for detecting quality of niaolukang particles. The formula of the niaolukang particle is as follows: preparing 1000g of leonurus, 1000g of eclipta, 1000g of plantago asiatica, 300g of junci medulla, 1000g of desmodium, 200g of liquorice, 1000g of rhizoma polygonati and 500g of rhizoma dioscoreae into granular formulation. In the method, quercetin (C15H1107) and kaempferol (C15H10O6) in desmodium are taken as a quality control index, and compared with stachydrine in the leonurus, the ingredients are stable in property, and generate small detection error. In addition, the high performance liquid chromatography is utilized for measuring content, so that the resolution rate is higher than that of other chromatography, the speed is high, and the measurement can be completed in ten minutes to dozens of minutes; the repeatability is high; a high performance liquid chromatography column can be used repeatedly; and the automatic operation is conducted, and the analysis accuracy is high. Therefore, the accuracy, the specificity and the credibility of a detection result in the quality control process of products are improved.

Description

technical field

[0001] The invention relates to the technical field of medicine detection, in particular to a quality detection method for Niaolukang granules. Background technique

[0002] Niaolukang Granules have the functions of clearing away heat and dampness, invigorating the spleen and kidney. It is used for the syndrome of stranguria caused by damp-heat in the lower energizer, spleen and kidney deficiency, difficulty urinating, phlegm and astringent pain; non-gonococcal urethritis sees the above-mentioned syndromes. The prescription of Niaolukang granule is: Motherwort 1000g, Eclipta 1000g, Plantain 1000g, Rush 300g, Desmodium 1000g, Licorice 200g, Polygonatum 1000g, Chinese yam 500g. Preparation method: The above eight flavors and yam are crushed into coarse powder, extracted twice with dilute ethanol under reflux, each time for 1.5 hours, filtered, combined filtrate, recovered ethanol under reduced pressure, concentrated to a relative density of 1.10-1.15 (80°C) T...