46 results about "Artery Endothelium" patented technology

The invention discloses a renal artery balloon catheter for local drug perfusion, and relates to the technical field of renal artery balloon catheters, the renal artery balloon catheter comprises an access unit, and the access unit comprises a connecting end, a perfusion joint arranged at one end of the connecting end, and a liquid injection joint arranged on the outer wall of the connecting end. The balloon has the advantages that a traditional integrally-injection-molded balloon is changed to be composed of multiple independent tubes, the balloon can be matched with the renal artery with the larger bending degree, the production cost of an enterprise can be reduced, the corrugated balloon formed through expansion and the concave-convex surface can disperse contact pressure, local compression on the intima is reduced, and the balloon has the good sealing effect. And the'grooves' of the waveform structure are in multi-point contact with the blood vessel wall, so that the friction force is increased, and the balloon is prevented from sliding under the impact of blood flow.

The invention relates to the field of medical instruments, in particular to a suction catheter with a shock wave thrombus breaking function, which comprises a shock wave catheter, a suction tube and a discharge mechanism, and a shock wave guide pipe is arranged in the suction pipe. According to the invention, charges are introduced into the annular electrode and the cylindrical electrode by starting the discharge mechanism, a large amount of charges are accumulated at the two ends of the positive electrode and the negative electrode to generate a strong electric field, neutral particles in a medium between the electrodes are ionized into plasma under the action of the strong electric field, and a discharge phenomenon occurs; rapid temperature change of plasmas and surrounding media generated in the discharging process causes rapid volume expansion and contraction of the surrounding media, the violent movement of particles in the media can generate pressure sound waves and transmit the pressure sound waves outwards through the media, and when the movement speed of the particles exceeds the propagation speed of the sound waves in the media, shock waves can be generated, so that the pressure sound waves are generated. When the shock wave catheter extends into the blood vessel of the human body, calcified plaques in the blood vessel can be efficiently crushed without damaging the endometrium of the blood vessel.

The utility model discloses a drainage hole with a function of preventing blood vessels from adhering to the wall. The drainage hole comprises a drainage hole body, an anti-injury block, a supporting ring, a drainage ditch and an arc-shaped cannula adhering face. A gap between every two adjacent damage blocks is a drainage ditch; each anti-damage block consists of an anti-damage table, an access slope, an access arc, an anti-damage arc I and an anti-damage arc II, wherein the anti-damage table is positioned at the upper part of the anti-damage block; the access slope is located outside the anti-damage block; the access arc is in transition connection between the access slope and the anti-damage table; the anti-damage arc I is positioned on the inner side of the anti-damage block; the anti-damage arcs II are located on the two sides of the anti-damage block. According to the utility model, the drainage holes can be effectively prevented from being blocked by endangium, so that the following problems are avoided: the treatment effect is reduced or even interrupted due to sudden drop of drainage quantity, and the life of a patient is endangered; due to the fact that drainage holes are blocked by endangium, the endangium is injured due to the high pressure difference between intravascular equipment and extracorporeal equipment; endovascular injury generates thrombus which endangers the life of a patient.

The invention belongs to the technical field of biological medicine, and particularly relates to application of lycium ruthenicum anthocyanin in preparation of a blood pressure lowering product. The invention provides application of lycium ruthenicum anthocyanin in preparation of a product for reducing blood pressure. The lycium ruthenicum anthocyanin is found to have an antihypertensive effect, can protect target organs such as heart and kidney, alleviate organ injury and reduce TG and LDL levels so as to reduce the risk of cardiovascular diseases, and is in direct proportion to dosage. The lycium ruthenicum anthocyanin has a pharmacodynamic mechanism of lowering blood pressure, lowering the level of angiotensin converting enzyme (ACE), reducing secretion of angiotensin II (AngII) and aldosterone (ALD), and regulating excessive activation of an RAAS system; the level of nitric oxide (NO) is improved, and vascular tension is reduced; the method is related to reduction of the thickness of the middle layer of the vascular intima and improvement of aortic remodeling, and has the advantage of multi-link and multi-target integral adjustment.

The application relates to the application of lycorine hydrochloride in the preparation of a medicine for inhibiting the proliferation of a neointimal in a blood vessel. Lycorine hydrochloride has the effect of inhibiting the proliferation of a neointimal in a blood vessel, and the effect is mainly realized by inhibiting the proliferation and migration of vascular smooth muscle cells. In the body, the results show that lycorine hydrochloride can significantly inhibit the intimal proliferation caused by left common carotid artery ligation, and in vitro experiments prove that lycorine hydrochloride can intervene in the proliferation, migration and phenotype transformation of VSMCs induced by PDGF-BB. Lycorine hydrochloride inhibits the proliferation, migration and phenotype transformation of VSMCs induced by PDGF-BB, and the proliferation of a neointimal in a blood vessel through a MAPKs signal path. The application provides data for preparing lycorine hydrochloride into a medicine for inhibiting the proliferation of a neointimal in a blood vessel, and is expected to be applied to the prevention and treatment of complications after percutaneous coronary intervention, such as restenosis or in-stent thrombosis, and can become a potential medicine for intervening in restenosis.

The utility model provides a kind of vascular stent, the device includes: first support, first support includes first support unit and first pipe body, first support unit is set on first pipe body, along the length direction of first pipe body extends, and stop and resist the outside wall of first pipe body, first pipe body is distributed with multiple first hollow holes of interval distribution;Second support, second support includes second support unit and second pipe body, second support unit is set on second pipe body, along the length direction of second pipe body extends, and stop and resist the outside wall of second pipe body, second pipe body is distributed with multiple second hollow holes of interval distribution;The end of second support is connected with first support, the lumen of first pipe body is communicated with the lumen of second pipe body.In the utility model, sufficient radial support force is provided while excellent flexibility is guaranteed, the mechanical stress stimulation to blood vessel intima is small, and the long-term patency of main branch and side branch is guaranteed.

The invention discloses a medicine balloon dilatation catheter which comprises a balloon and a support arranged outside the balloon, the support is in a net pipe shape and can dilate and contract along with the balloon, the dilatation diameter of the support is smaller than the dilatation diameter of the balloon during dilatation, and the dilatation catheter further comprises a medicine coating coated on the outer portion of the balloon. The drug coating comprises a plurality of magnetic drug particles; in a contraction state, the medicine particles are positioned between the balloon and the stent; in the expansion state, part of the sacculus swells out of the stent from the meshes of the stent to form a plurality of protruding parts, and the medicine particles are located on the protruding parts respectively. According to the drug balloon dilatation catheter, under the action of an in-vitro magnetic field, free drug particles generated in the dilatation process of the dilatation catheter can migrate to a vascular intima, meanwhile, the magnetic field can also prevent the drug particles squeezed into a blood vessel from being washed by blood to be separated from the blood vessel, and drug loss in the dilatation process can be reduced. And the stent is arranged outside the balloon, so that the medicine loss of the dilating catheter in the conveying process can be reduced.

The present invention discloses a stent graft for reducing rupture pressure, comprising a main body coating, an annular support frame axially fixed on the main body coating in sequence, the main body coating and the annular support frame sequentially form a first tube body, a second tube body and a third tube body from the proximal end to the distal end, the second tube body is provided with a decompression portion for reducing the pressure at the rupture of the blood vessel, the decompression portion is recessed into the second tube body or the decompression portion is a soft structure. The present invention provides a stent graft for reducing rupture pressure that can greatly reduce the squeezing of the stent on the rupture, avoid further expansion of the rupture of the blood vessel intima, and even cause rupture of the blood vessel.

The invention relates to a vascular intima stripping device.The vascular intima stripping device comprises an inner core tube, a middle tube, a stripping component, an outer tube, a first operating handle and a second operating handle, the radial expansion degree of the stripping component can be flexibly adjusted to adapt to the inner diameter of a lesion blood vessel, damage to the blood vessel during stripping operation is greatly reduced, and the stripping efficiency is improved. The inner film can be clamped more easily when the inner film is twisted, and the clamped inner film can be effectively prevented from falling off in the stripping process and the device withdrawing process. The device is simple in structure, convenient to operate and high in controllability, the axial length of the stripping part can be increased, the working area of the stripping part is larger, the device is suitable for stripping some intima which is long and high in stripping difficulty, the operation efficiency is improved, the operation time is shortened, and pain of a patient is relieved.

This invention relates to a vascular stent for the visceral region of the abdominal aorta, comprising an interconnected proximal non-degradable segment and a distal degradable segment. The proximal non-degradable segment includes a non-degradable metal skeleton and a covering structure. The distal degradable segment is a degradable bare skeleton. The proximal non-degradable segment corresponds to the location of the primary tear in the visceral region of the abdominal aorta, and the distal degradable segment corresponds to the location of branch vessels in the visceral region of the abdominal aorta. This invention is applicable to abdominal aortic dissection anatomical features, where the proximal stent segment is non-degradable and covered, while the distal visceral segment is degradable but not covered. It promotes false lumen thrombosis by sealing the primary tear through covering, while maintaining patency of branch vessels in the visceral segment by not covering. Simultaneously, a drug layer is attached to the covering of the proximal stent segment to actively promote intimal repair.

The invention relates to the technical field of medical instruments, in particular to a common carotid artery piercing sheath with an inflatable balloon, which comprises a first catheter and a second catheter, the first catheter is communicated with the second catheter, and the first catheter is used for being inserted into an artery and used for guiding blood in the artery to enable the blood to flow into the second catheter; a limiting assembly is arranged on the outer side wall of the first catheter and is used for inserting the first catheter into a blood vessel and blocking and closing the blood vessel; the tail end of the second catheter is connected with an adjusting assembly, and the other end, away from the first catheter, of the second catheter is connected with an external conveying pipe. The air bag is divided into a plurality of independent inflation cavities by the diaphragms, and can be inflated and expanded in a partitioned mode in sequence, so that the air bag can adapt to the shape of a blood vessel, uniform sealing attached to the wall of the blood vessel is achieved, and local compression or incomplete sealing caused by deviation of the air bag is avoided; suddenly impact of one-time overall expansion of a traditional air bag on the blood vessel wall is avoided through partitioned inflation, and the risk of injury or spasm of the endangium is reduced.

The utility model relates to a detachable papillary balloon and balloon catheter, including inner layer balloon, outer layer balloon, convex part structure, the fluid passage is formed between outer layer balloon, inner layer balloon, is provided with the hole on outer layer balloon, the convex part structure includes convex part main part, barb, drug loading membrane, the hole of outer layer balloon is blocked up with convex part main part being connected on outer layer balloon, the barb is connected on convex part main part, the drug loading membrane is coated on convex part main part and / or barb, when fluid acts on convex part main part through fluid passage, hole, convex part main part can be separated from outer layer balloon. The utility model utilizes the feature that the convex part structure is less in contact with calcified lesion or narrow site, plays the pressure amplification effect, and better expands and crushes plaque, through the separation of the convex part structure and the balloon, the separated convex part structure is anchored in the vascular intima, thereby continuously administering, short residence time, long administration duration, and better treatment effect.

The invention discloses a drainage hole with a function of preventing blood vessels from adhering to the wall. The drainage hole comprises a drainage hole body, an anti-injury block, a supporting ring, a drainage ditch and an arc-shaped cannula adhering face. A gap between every two adjacent damage blocks is a drainage ditch; each anti-damage block consists of an anti-damage table, an access slope, an access arc, an anti-damage arc I and an anti-damage arc II, wherein the anti-damage table is positioned at the upper part of the anti-damage block; the access slope is located outside the anti-damage block; the access arc is in transition connection between the access slope and the anti-damage table; the anti-damage arc I is positioned on the inner side of the anti-damage block; the anti-damage arcs II are located on the two sides of the anti-damage block. According to the invention, the drainage holes can be effectively prevented from being blocked by endangium, so that the following problems are avoided: the treatment effect is reduced or even interrupted due to sudden drop of drainage amount, and the life of a patient is endangered; due to the fact that drainage holes are blocked by endangium, the endangium is injured due to the high pressure difference between intravascular equipment and extracorporeal equipment; endovascular injury generates thrombus which endangers the life of a patient.

The utility model particularly relates to an absorbable stent which comprises a first stent body and a second stent body, the first stent body is of a tubular structure and comprises a plurality of metal wires which are woven in a staggered mode, and the metal wires comprise one or two of molybdenum wires and molybdenum alloy wires. The second stent is arranged on the peripheral surface of the first stent, and the second stent comprises absorbable polymer filaments. The absorbable stent disclosed by the utility model has good structural performance, realizes that the whole body of the stent is visible in the pushing and releasing process, and is beneficial to avoiding the defects that the continuous external expansion force causes damage to the endovascular intima, the inflammation of the endovascular intima is possibly induced, restenosis is caused by excessive hyperplasia and the like, and the absorbable stent is suitable for being used in the medical field. Therefore, the problem that an existing absorbable intravascular stent is poor in using effect can be effectively solved.

The application discloses a thrombus taking device with a composite mesh structure, a support body of which adopts a woven structure and is arranged in a multi-segment structure and comprises a support outer layer and an inner layer. The outer layer is a large-mesh thrombus embedding structure, which is beneficial to the large thrombus to burst in to provide strong anchoring force and realize efficient embedding; the inner layer is a small-mesh leakage prevention structure, which is used for intercepting the thrombus fragments falling off in the thrombus taking process and preventing secondary embolism. The thrombus taking device takes into account the embedding and leakage prevention of the thrombus through the composite mesh structure, and the success rate and safety of thrombus taking are improved. The woven structure and the multi-segment design reduce the contact area and pulling damage of the support and the blood vessel wall, the soft spring arranged at the distal end can buffer the contact stress and reduce the risk of blood vessel intima damage. Meanwhile, the small-mesh independent unit of the inner layer, the multi-segment leakage prevention thrombus bundle port or the double-layer leakage prevention thrombus structure enhances the radial support force of the middle part of the woven support, guarantees the adhesion and embedding stability of the woven support in the tortuous blood vessel, avoids the displacement of the support or the falling off of the thrombus, and is beneficial to improving the prognosis of patients.

The invention relates to the technical field of heart and cerebral vessels, in particular to a heart and cerebral vessel intelligent diagnosis model generation method based on multi-source big data analysis. Comprises: establishing an initial cardiovascular and cerebrovascular diagnosis model; determining the health risk level of the cardiovascular and cerebrovascular diseases and judging a corresponding processing mode; the method comprises the following steps: respectively acquiring image data of a plurality of cardiovascular vessels and cerebrovascular vessels of a patient, segmenting and identifying a carotid artery image acquired by mobile ultrasound through a blood vessel deep learning model, observing vascular intimal smoothness and blood flow velocity, and generating a simulated cardiovascular tube diameter change rate; judging and detecting the volume of a plaque in the cardiovascular image data, or adjusting a health risk level; generating a blood vessel health characterization value; and adjusting the pipe diameter change rate correction value, or sending out health early warning and updating the initial cardiovascular and cerebrovascular diagnosis model. According to the method, the accuracy of the intelligent cardiovascular and cerebrovascular diagnosis model is further improved while the rate of primary diagnosis of cardiovascular diseases is effectively improved.

The invention discloses a dense hole type blood vessel cannula. The cannula comprises a cannula body, a cannula main guide hole, a special-shaped drainage hole composed of a round hole and an anti-blocking hole, a main drainage groove and a drainage groove. By the adoption of the structure, when equipment such as ECMO is used for drainage operation, the phenomenon that a drainage hole is blocked by a vascular intima, namely, the wall adherence phenomenon occurs can be effectively avoided, and then the following problems are fundamentally avoided: 1, due to sudden drop of drainage amount, the treatment effect is reduced or even interrupted, and the life of a patient is endangered; 2, as the drainage hole is blocked by the endovascular intima, the endovascular intima is injured due to the high pressure difference between intravascular equipment and extracorporeal equipment; 3, thrombus generated by injury of endangium endangers the life of a patient; meanwhile, the blood drainage efficiency is greatly improved, and operation is easy and convenient.

The invention relates to a bead string type balloon structure for removing coronary artery interlayer hematoma through balloon withdrawing and a using method, the bead string type balloon structure comprises a connecting pipe and at least one balloon body, the balloon body is arranged on the connecting pipe, the balloon body is communicated with the connecting pipe, and the connecting pipe is connected with the connecting pipe. The balloon body comprises a first inclined part, a first contact part and a second inclined part, the right end of the first inclined part is connected with one end of the first contact part, and the other end of the first contact part is connected with the left end of the second inclined part; the first inclined part, the first contact part and the second inclined part form a protruding structure, and the section length of the first contact part in the extending direction of the connecting pipe is smaller than the preset size. Different from the prior art, the contact area between the balloon body and the endovascular intima is reduced, the withdrawing resistance is reduced, the contact between the balloon body and the endovascular intima is reduced, and excessive hyperplasia of the endovascular intima is avoided.

The invention relates to the technical field of medical apparatus and instruments, in particular to a viscous hydrogel injection system for abdominal aortic dissection, comprising: a cannula internally provided with a puncture member capable of puncturing the endangium of a patient; the traction assembly is connected with the sleeve, the traction assembly can stabilize the sleeve when the puncture part performs puncture action, and the traction assembly comprises a traction part which is arranged in the sheath tube and can extend to the outside of the sheath tube from the side hole; the traction assembly further comprises an expansion piece connected with the traction piece. The expansion piece comprises a balloon arranged on the traction piece, and the balloon enables the traction piece to be stable through expansion.

The present application relates to the technical field of medical instruments and particularly to a three-cavity microcatheter. The three-cavity microcatheter comprises: a first tube body, wherein a guide wire cavity is formed in the first tube body; a second tube body; a third tube body, wherein at least one guide wire outlet is formed in a sidewall of the far end of the first tube body, the guide wire outlet is in communication with the guide wire cavity, and a far end part of the second tube body, a far end part of the first tube body, and a far end part of the third tube body are arranged side by side in a flat shape such that, when the three-cavity microcatheter enters an inner space of the tunica vasculosa, the at least one guide wire outlet faces the tunica intima and / or the tunica media; and a positioning mark, wherein the second tube body and / or the third tube body are provided with the positioning mark, and the positioning mark is configured for positioning the guide wire outlet of the first tube body. The solutions provided by the present application enable a directional puncture of the puncture guide wire reentering the true vascular lumen from the subintimal space, increasing the success rate of one-time surgery.

This invention provides a method and system for measuring vascular intima-media thickness based on neural networks and the shortest path algorithm. The method includes: acquiring and preprocessing an ultrasound image of the vessel to be measured; inputting the preprocessed ultrasound image into a trained neural network model to obtain the boundary probability map and orientation field map output by the neural network model; constructing a graph structure using pixels of the ultrasound image as nodes and adjacency relationships between pixels as edges, and dynamically assigning weights to the edges in the graph based on the boundary probability map and orientation field map to obtain a weighted graph; setting a start point and an end point for the vessel boundary to be searched in the weighted graph, and searching for the vessel boundary path based on the shortest path algorithm; calculating the average distance between the lumen-intima boundary and the media-adventitia boundary based on the vessel boundary path, and outputting the vascular intima-media thickness measurement result; which is beneficial for improving accuracy and robustness, has a high degree of automation, and good repeatability.

The invention belongs to the field of dense net stents, and particularly relates to a dense net stent with a phosphorylcholine coating, the dense net stent comprises a dense net section formed by weaving a plurality of metal wires, positioning sections protruding outwards are formed at the two ends of the dense net section, and ray marking points are arranged on the positioning sections; the phosphorylcholine coating is formed on the end face, attached to the blood vessel wall, of the dense net section, surface modification is conducted on the metal wire, and the phosphorylcholine coating is used for simulating a human cell membrane structure, remarkably reducing the risk of platelet adhesion and thrombosis, improving biocompatibility, reducing the vascular intimal inflammatory reaction, supporting faster endothelial healing and shortening the recovery cycle of a patient. And the occurrence of postoperative complications is reduced. According to the method, plasma is combined to activate the metal surface, the wettability of the coating is improved, it is ensured that the intersections of the net wires are evenly covered, and in the chemical grafting method process, the dense net section rotates at a constant speed with the assistance of a negative pressure adsorption device, and coating solution accumulation or coating missing is avoided.

The utility model relates to the technical field of medical intervention equipment, and provides an ultrasonic ablation device which comprises an ablation generating head and an ablation catheter. The ablation generation head comprises an ultrasonic transducer arranged in the ablation generation head and a peripheral balloon arranged on the peripheral part; one end of the ablation catheter is connected with the ablation generating head, and the other end is connected with the outdoor unit equipment; a pressure supply liquid path communicated with the peripheral balloon and a temperature control liquid path for controlling the temperature of the ablation generating head are arranged in the ablation catheter; an anti-skid positioning part is also arranged in the peripheral wall of the peripheral balloon; and the peripheral balloon can be expanded when the pressure supply liquid path is pressurized and can be retracted when the pressure supply liquid path is decompressed. The ultrasonic ablation device can be tightly attached to the inner wall of a pulmonary artery blood vessel of a patient through the anti-skid positioning part, the effect of accurately anchoring the ablation generating head and a to-be-ablated affected part is achieved, and real-time temperature control can be conducted on the ablation generating head through the temperature control liquid path; the problems of vascular intimal hyperplasia and stenosis caused by vascular wall injury due to ablation local high temperature are avoided.

The present invention relates to the technical field of surgical instruments used in donor organ transplantation. Disclosed is an integrated puncture and perfusion catheter for perfusion of donor abdominal organs for transplantation, comprising: a puncture cylinder, wherein a reservoir is fixedly connected to a puncture end of the puncture cylinder; and further comprising: a puncture and perfusion switching mechanism, wherein the puncture and perfusion switching mechanism is arranged at the center of the puncture cylinder, and is used for freely switching the puncture and perfusion functions of the puncture cylinder at the same position. Through cooperation of provided structures such as a first rack, a second rack, and a guide member, the rotation of a gear disc can be used to control the first rack and the second rack to slide in opposite directions of the puncture cylinder, such that a puncture tip moves backward upon the completion of penetration to provide clearance, thereby avoiding damage to tunica intima caused by retention of the puncture tip, and improving the viability of a harvested organ; and the second rack carries a support tube by means of the guide member to move towards the perfusion position, and the support tube replaces the puncture tip at the puncture position, such that a perfusion pipe is prevented from deviating from a puncture port, thereby minimizing perfusate usage costs.

The application discloses a kind of venous bridge blood vessel dilating devices and methods, setting is made so that the venous bridge blood vessel implanted in human body is dilated, including dilating balloon, inflation pump, pressure sensor and controller;Dilating balloon has shrinkage state and fullness state, dilating balloon is suitable for the radial expansion of venous bridge blood vessel when fullness state;Pressure sensor is set to be suitable for detecting the intimal pressure signal of venous bridge blood vessel, inflation pump is communicated with dilating balloon and is used to inflate or deflate dilating balloon;Controller is electrically connected with pressure sensor and inflation pump, and responds to the intimal pressure signal output by pressure sensor to control inflation pump to execute inflation action or deflation action.This venous bridge blood vessel dilating mode is compared with the mode of using syringe to control pressure in prior art, and the pressure control effect is better, the venous bridge blood vessel can be efficiently, conveniently and safely dilated under stable ideal pressure, the integrity of the intimal function of the venous bridge blood vessel is protected, and the patency rate is improved.

The invention belongs to the technical field of minimally invasive interventional medical instruments, and discloses a medicine-carrying balloon catheter for treating pulmonary artery stenosis caused by takayasteritis, which comprises a handle, one end of the handle is fixedly connected with one end of a near-end rod, the other end of the near-end rod is fixedly connected with one end of a far-end rod, the other end of the far-end rod is fixedly connected with a balloon, and the balloon is fixedly connected with a catheter. The balloon is divided into a circular truncated cone shape and a cylindrical shape; the drug coating is arranged on the outer surface of the balloon, and the drug coating is used for carrying treatment drugs; the triangular wires are arranged on the outer side wall of the balloon in the length direction of the balloon. Through balloon dilatation and the micro-cutting effect of the triangular wire, the pulmonary artery stenosis part is effectively dilated, meanwhile, anti-inflammatory and anti-proliferation drugs are released in a targeted mode, inflammatory response and vascular intimal hyperplasia are inhibited, the restenosis occurrence rate is reduced, and the balloon dilatation triangular wire has the advantages of being high in safety and adaptability, remarkable in treatment effect and the like.

The application discloses a coated stent. The coated stent comprises a supporting framework and a degradable coated structure, the supporting framework is an elastic net structure, the coated structure comprises a wrapping piece and an elastic closed film piece, the wrapping piece is coated on the net wire of the supporting framework, and the elastic closed film piece is connected in each mesh of the supporting framework respectively, and the elastic closed film piece is used for closing the corresponding mesh. After the coated stent is implanted in a blood vessel, when the coated structure is degraded and absorbed, the vascular endothelium can carry out normal endothelialization process, in the treatment of vascular stenosis operation process, the coated stent can easily pass through the stenosis part of the blood vessel, and the risk of thrombosis in the coated stent and edge stenosis of the coated stent is reduced. The degradable coated structure made of biodegradable material is used for temporarily plugging the perforation, and the coated structure is degraded by the human body after a long time, so that the vascular restenosis is avoided, and the risk of vascular intimal hyperplasia is reduced.

The invention discloses a bent carotid artery intubation tube. A tube body comprises a long-section tube; the short-section pipe is arranged on the lower portion of the long-section pipe, the angle C between the long-section pipe and the short-section pipe is larger than or equal to 90 degrees and smaller than or equal to 120 degrees; the bending part is arranged between the long-section pipe and the short-section pipe; the shallow groove is formed in the middle of the short-section tube, and the shallow groove is used for fixing and bundling a blood vessel blocking band; and an inner diameter channel is arranged among the long-section pipe, the short-section pipe and the bent part in a penetrating manner. The catheter body provided by the invention is convenient for an operator to complete left common carotid artery intubation in a relatively deep and narrow space, so that the injury risk of vascular intima and the injury of surrounding tissues are reduced, and the operation safety is ensured; the blood vessel blocking belt stably fixes the arterial cannula at the arterial cannula groove, and the cannula is not prone to blood leakage and slipping.

The invention discloses a peripheral intravascular stent restenosis or occlusion opening catheter, and relates to the technical field of medical instruments, blood vessel foreign body forceps and operating handles, the catheter of the blood vessel foreign body forceps is an adjustable bent catheter, a through hole is formed in the forceps head end of the blood vessel foreign body forceps, a guide wire penetrates through the through hole, teeth are oppositely arranged on the forceps head of the forceps head end, and the operating handles are arranged on the teeth. And the operating handle can control the bending degree of the adjustable bending catheter and the opening and closing of the forceps head. According to the intravascular reocclusion opening system in the stent, the rotating angle of the front-end forceps head can be adjusted and controlled through the guide wire, restenosis contents (hyperplasia endometrium and calcified plaques) in the stent can be occluded, and the purpose of safely opening the intravascular restenosis and completely occluded blood vessels in the stent is achieved by combining the guide wire penetrating through the middle of the system; the problem of in-stent restenosis caused by intracavity treatment is solved in a minimally invasive mode, and surgical vascular bypass is avoided.

The invention provides an open-loop dense net stent for repairing endovascular intima, and relates to the technical field of artery implantable medical instruments, the open-loop dense net stent for repairing endovascular intima is cylindrical and comprises a plurality of sine curve spiral open-loop structures, and the structures deform to adapt to tortuous blood vessels. Compared with a dense net stent in the prior art, the dense net stent has the advantages that the rigidity of the whole structure is high, the dense net stent is difficult to fully unfold in a continuously bent area or an area with non-uniform blood vessel diameter, and the wall adhesion is poor, so that the rigidity of the whole structure of the dense net stent is greatly improved. Through the open-loop design (partial or all inflection points of the sine open-loop are not mutually connected) and the independent sine-shaped ring structure, the stent is segmented to adapt to different bending angles and blood vessel diameters, gaps between the stent and the blood vessel wall are reduced, and connection of the dense net units and the sine-shaped rings also ensures blood flow guidance.