68 results about "Calcified lesion" patented technology

Various embodiments of the systems, methods, and devices are provided for controlled operation of an intravascular lithotripsy system for breaking up calcified lesions in an anatomical conduit. More specifically, control arrangements are disclosed concerning managing and / or providing and / or terminating provision of electrical energy to generate an electrical arc between a set of spaced-apart electrodes submerged within a contained fluid.

The present invention provides a system and method for treating tight, hard-to-cross calcified lesions in which an angioplasty balloon is used to dilate the lesions and provide shock waves to restore normal blood flow in a patient's artery. An exemplary device includes an elongated tube and a balloon wrapped circumferentially around the tube and sealed to a distal end of the tube. During treatment, the device is advanced into a patient's vasculature and the balloon is inflated with conductive fluid such that the balloon is fixed to walls of the vasculature proximal to the calcified lesion. The balloon includes at least one low-profile emitter positioned near the distal end of the balloon, which may be activated to generate shock waves to break loose calcifications in the lesion. After calcium in the tight lesion has been modified, the balloon can be deflated and advanced further into the lesion to continue treatment.

The invention discloses a drug eluting stent, which comprises a stent main body and a plurality of thorn-shaped components, the stent main body has a radially compressible contraction state and a radially self-expanding expansion state to support blood vessels, and the plurality of thorn-shaped components are arranged on the outer surface of the stent main body and coated with a drug coating for inhibiting vascular restenosis. The spine-shaped components are arranged on the stent body and are configured to protrude towards the outer side of the stent body from the outer surface of the stent body to penetrate into calcified lesions on the inner wall of a blood vessel when the stent body is switched from the contraction state to the expansion state, each spine-shaped component is provided with a part capable of generating elastic deformation, and the spine-shaped components are configured to be capable of generating deformation in a self-adaptive mode according to the thickness of the contacted calcified lesions. Therefore, the medicine can be uniformly distributed in a target lesion area, and the utilization rate of the medicine and the treatment effect are remarkably improved.

A medical device may include an elongated body having a distal elongated body portion and a central longitudinal axis. The medical device may include a balloon positioned along the distal elongated body portion. The balloon may be configured to receive a fluid to inflate the balloon such that an exterior balloon surface contacts a calcified lesion within a patient's vasculature. The medical device may include one or more pressure wave emitters positioned along the central longitudinal axis of the elongated body. The one or more pressure wave emitters may be configured to propagate at least one pressure wave through the fluid to fragment the calcified lesion. At least one pressure wave emitter may include an optical fiber configured to transmit laser energy into the balloon. The laser energy may be configured to create a cavitation bubble in the fluid.

The invention discloses a drug eluting stent, which comprises a stent main body and a plurality of thorn-shaped components, the stent main body has a radially compressible contraction state and a radially self-expanding expansion state to support blood vessels, and the plurality of thorn-shaped components are arranged on the outer surface of the stent main body and coated with a drug coating for inhibiting vascular restenosis. The spine-shaped components protrude from the outer surface of the stent body to the outer side of the stent body so as to penetrate into calcification lesions on the inner wall of a blood vessel when the stent body is switched from the contraction state to the expansion state, each spine-shaped component comprises a spine section, and the spine section at least comprises a first section and a second section of which the roots are connected together. The first section and the second section are attached to each other in a natural state to form a compact structure, and can elastically deform and be separated relative to the root part when subjected to opposite acting force from calcification lesion, so that the calcification lesion can be punctured at a larger angle, the slippage risk is reduced, the puncturing efficiency is improved, and the puncturing effect is improved. Therefore, the effect of inhibiting vascular restenosis is enhanced.

Various embodiments of the systems, methods, and devices are provided for controlled operation of IVL for breaking up calcified lesions in an anatomical conduit. More specifically, control arrangements are disclosed concerning managing and / or providing electrical energy to generate an electrical arc between a set of spaced-apart electrodes disposed within a fluid-filled balloon, creating stable and constant, or slightly increasing, pressure output over at least 300 voltage pulses. Control arrangements disclosed further determine whether an electrical arc was successfully generated.

The invention provides a nicking guide wire, a nicking balloon assembly and an intervention device. The nicking guide wire comprises a guide wire shaft and a cutting unit. The cutting unit has an expansion state and a compression state, the far end of the cutting unit is fixed to the guide wire shaft, and the near end of the cutting unit is of an expandable annular structure. The nick guide wire is configured such that when the nick guide wire cooperates with the balloon catheter, at least part of the distal end of the balloon catheter enters the interior of the cutting unit through the annular structure. The indented guide wire is provided with the cutting unit, the cutting unit is combined with a balloon catheter to achieve the balloon cutting function, due to the fact that the indented guide wire is separated from a balloon body, the trafficability and flexibility of the product are better than those of products such as a cutting balloon, and when the indented guide wire is applied to treatment of intracranial vessel moderate calcification lesions, blood vessel injuries are not likely to be caused; and operative complications are reduced. For serious calcification lesions of cardiovascular and peripheral blood vessels, plaque expansion can be achieved without additionally using a CTO balloon for pre-expansion, and the operation cost and the operation difficulty are reduced.

The invention relates to a cavity targeted pulse therapy device, belongs to the technical field of medical instruments, and solves the problems that in the prior art, a shock wave balloon catheter is poor in passing ability, and calcification lesions which cannot be passed by the balloon catheter cannot be effectively treated. The device comprises a catheter partially penetrating into the body of a patient, the catheter comprises a balloon, a shock wave generator and a directional reinforcing component, the shock wave generator and the directional reinforcing component are arranged in the balloon, the shock wave generator is arranged in front of the directional reinforcing component or arranged in the directional reinforcing component, and the directional reinforcing component shrinks along with expansion of the balloon. By arranging the directional reinforcing component, the reverse shock wave generated by the shock wave generator is reflected and then superposed with the forward shock wave energy, so that the energy loss can be reduced, the forward impact force can be remarkably improved, and the treatment effect can be improved.

The dilatation balloon comprises a catheter, a balloon body arranged on the catheter in a sleeving mode and a support arranged on the balloon body in a sleeving mode, and the support comprises a support body arranged outside the balloon body in a sleeving mode and a plurality of anchoring components arranged on the outer surface of the support body. The anchoring components are configured to penetrate into calcification lesion of the inner wall of a blood vessel when the stent body is in an expansion state, the capsule forms an outline with the middle portion obviously protruding relative to the two end portions in a full state, the catheter is provided with a first limiting structure, and the stent body is correspondingly provided with a second limiting structure. The first limiting structure and the second limiting structure can be matched with each other so as to allow the catheter and the stent body to generate certain relative movement in the axial direction, and local pressurization and expansion are conducted on a specific area of the stent body through the middle portion of the bag body. Therefore, not only are the fitness and anchoring effect of the stent in irregular calcification lesions improved, but also the pertinence and safety of treatment are enhanced.

Various embodiments of the systems, methods, and devices are provided for controlled operation of an intravascular lithotripsy system for breaking up calcified lesions in an anatomical conduit. More specifically, control arrangements are disclosed concerning managing and / or providing electrical energy to generate an electrical arc between a set of spaced-apart electrodes disposed within fluid-fillable member are disclosed.

A medical device may include an elongated body, a balloon positioned at a distal portion of the elongated body, and one or more pressure-wave emitters positioned along a central longitudinal axis of the elongated body within the balloon. The one or more pressure-wave emitters may be configured to propagate pressure waves radially outward through the fluid to fragment a calcified lesion at the target treatment site. The at least one of the one or more pressure-wave emitters may comprise an electronic emitter including a first electrode and a second electrode. The first electrode and the second electrode may be arranged to define a spark gap between the first electrode and the second electrode, and the second electrode may comprise a portion of a hypotube.

Various embodiments of systems, methods, and devices for controlled operation of an endolithotripsy system for fragmenting calcification lesions in anatomical catheters are provided. More specifically, control arrangements are disclosed relating to managing and / or providing and / or providing terminating electrical energy to generate an arc between a set of spaced apart electrodes submerged within a contained fluid.

Disclosed is an intravascular calcification lesion ultrasonic-powered rotary grinding device. The technical problem to be solved is to improve the safety of surgeries and reduce costs. In the present invention, a rotary grinding head is provided, and from the proximal end to the distal end, an ultrasonic motor system, a first-order transmission acceleration mechanism, a second-order transmission acceleration mechanism, and a rotary grinding head, which are connected in sequence, are provided. The rotary grinding head has a rotating speed of 60,000 rad / min to 120,000 rad / min. Compared with the prior art, the present invention adopts an ultrasonic motor to convert electrical energy into rotational mechanical energy, to drive the transmission acceleration mechanism to achieve the rotation of the rotary grinding head, and is used for dredging or improving severely narrow and severely calcified or fibrotic atherosclerotic lesions in coronary arteries. The rotary grinding head has low transmission noise in high-speed rotation, reducing the frictional heat retained in a human body caused by rotary grinding, reducing the amount of cooling and lubricating solution input into the human body, and reducing the metabolic burden on human kidneys. The present invention has safety, reliability, a simple structure, and low costs.

The present invention provides a medical robot operating device, which relates to the field of medical robot technology. The present invention includes a rotating component, a transmission component, a passive component, a sensor and a shell; the rotating component is installed outside the shell; the passive component is installed inside the shell, and the rotating component drives the passive component to perform rotational motion through the transmission component; the sensor is installed inside the shell, and is used to monitor the real-time motion state of the passive component, and then transmit it to an external controller, and the controller controls the medical robot execution end to perform the operation of delivering the interventional instrument. The interventional instrument is controlled to move forward or backward by the rotating component, which is convenient to operate and easier to achieve precise control of the progressive distance; in addition, the rapid switching of the sliding direction of the rotating component can achieve rapid back and forth shaking of the interventional instrument, thereby realizing the "stabbing" action commonly used in interventional surgery, which is particularly beneficial for the interventional instrument to pass through calcified lesions or blood vessels with complex lesions.

Provided are a catheter (1) for treating coronary artery and peripheral artery calcification lesions. A calcification lesion tube (7) is fixedly connected to the rear end of the catheter, a cleaning tube (6) is fixedly connected to the rear end of the calcification lesion tube (7), and a guide rod (4) is fitted and connected to the interior of the catheter (1). When a stent mesh (2) is sleeved on the surface of a shock wave balloon (3), a connecting rod (24) may drive a fitting plate (31) and a rubber base (32) to enter the interior of a connecting base (26), such that the fitting plate (31) may be fitted into the interior of a fitting base (25) to connect and use the connecting base (26) and the connecting rod (4), which can increase a friction force between the connecting rod (4) and the connecting base (26), and can allow the stent mesh (2) to be better connected and used with the shock wave balloon (3). When the shock wave balloon (3) drives the stent mesh (2) to expand, the stent mesh (2) may fit and support an affected area of a patient; when the shock wave balloon (3) contracts, the connecting rod (4) may be separated from the connecting base (26), such that the shock wave balloon (3) and the stent mesh (2) are relatively stable when used in a sleeving manner.

A medical energy guide wire comprises a head end and a guide wire pushing rod, an energy discharge electrode assembly is axially arranged at the far end of the guide wire pushing rod, the guide wire pushing rod is of a cavity structure, the cavity structure forms a liquid inlet channel, the far end of the guide wire pushing rod is a hollow-out section of the guide wire pushing rod of a hollow-out structure, and a liquid inlet is formed in the near end of the guide wire pushing rod. The mode that the electrode ring and the guide wire are combined is adopted, a shock wave emission channel is established, a shock wave emission path of the energy guide wire takes the guide wire as the axis, shock waves of the energy guide wire form a passage capable of transmitting energy after liquid injection, energy is emitted to the periphery of the electrode, the caliber of a calcification narrow channel is expanded, calcification lesions are loosened, and the calcification effect is improved. The energy can cover a wider lesion area and act on the lesion area more evenly, local damage to the blood vessel wall is reduced, large-range calcification lesions can be treated more effectively, the strength and direction of shock waves can be better controlled in the operation process, the success rate of an operation is remarkably increased, and the operation time of the operation is shortened.

Various embodiments of systems, methods, and devices are provided for the controlled operation of an endovascular spallation system for destroying calcified lesions within an anatomical conduit. More specifically, control mechanisms are disclosed for managing and / or providing and / or terminating the supply of electrical energy to generate an electrical arc between a pair of spaced electrodes immersed within a contained fluid.

A medical energy guide wire comprises a head end and a guide wire pushing rod, an energy discharge electrode assembly is axially arranged at the far end of the guide wire pushing rod, the guide wire pushing rod is of a cavity structure, the cavity structure forms a liquid inlet channel, the far end of the guide wire pushing rod is a hollow-out section of the guide wire pushing rod of a hollow-out structure, and a liquid inlet is formed in the near end of the guide wire pushing rod. The mode that the electrode ring and the guide wire are combined is adopted, a shock wave emitting channel is established, a shock wave emitting path of the energy guide wire takes the guide wire as the axis, the shock wave emits energy to the periphery of the electrode through a passage which is formed after liquid injection and can transmit energy, the caliber of a calcification narrow channel is expanded, calcification lesions are loosened, and the calcification effect is improved. The energy can cover a wider lesion area and act on the lesion area more evenly, local damage to the blood vessel wall is reduced, large-range calcification lesions can be treated more effectively, the strength and direction of shock waves can be better controlled in the operation process, the success rate of an operation is remarkably increased, and the operation time of the operation is shortened.

An ultrasound diagnostic apparatus includes an ultrasound transmission and reception unit that transmits and receives ultrasound waves to and from a subject and that generates a reception signal, an ultrasound information generation unit that generates a plurality of types of ultrasound information based on the reception signal, a detection and measurement unit that detects and measures a lesion based on the plurality of types of ultrasound information, and a lesion / risk information analysis unit that analyzes a state of the lesion based on a measurement result obtained by the detection and measurement unit. The detection and measurement unit includes at least one of a set of a mass lesion detection unit and a mass lesion measurement unit, or a set of a calcified lesion detection unit and a calcified lesion measurement unit.

An ultrasound diagnostic apparatus includes an ultrasound transmission and reception unit that transmits and receives ultrasound waves to and from a subject and that generates a reception signal, an ultrasound information generation unit that generates a plurality of types of ultrasound information based on the reception signal, a detection and measurement unit that detects and measures a lesion based on the plurality of types of ultrasound information, and a lesion / risk information analysis unit that analyzes a state of the lesion based on a measurement result obtained by the detection and measurement unit. The detection and measurement unit includes at least one of a set of a tumorous lesion detection unit and a tumorous lesion measurement unit, a set of a fibrotic lesion detection unit and a fibrotic lesion measurement unit, a set of a calcified lesion detection unit and a calcified lesion measurement unit, or a set of a fatty liver detection unit and a fatty liver measurement unit.

To provide a medical device which executes treatment on a calcification plaque lesion in a blood circulatory system of a patient.SOLUTION: The medical device may comprise an elongate body, a balloon positioned at a distal portion of the elongate body, and one or more pressure wave emitters positioned along a central longitudinal axis of the elongate body within the balloon. The one or more pressure wave emitters may be configured to propagate pressure waves radially outward through a fluid to break up calcified lesions at a target treatment site. At least one of the one or more pressure wave emitters may comprise an electron emitter comprising a first electrode and a second electrode. The first electrode and the second electrode may be arranged to define a spark gap between the first electrode and the second electrode, and the second electrode may comprise a part of a hypotube.SELECTED DRAWING: Figure 1

Various embodiments of the systems, methods, and devices are provided for controlled operation of an intravascular lithotripsy (“IVL”) system for breaking up calcified lesions in an anatomical conduit. More specifically, control arrangements are disclosed concerning managing and / or providing electrical energy to generate an electrical arc between a set of spaced-apart electrodes disposed within a fluid-fillable member, wherein the IVL system may be powered by an AC power source and / or a DC power source.

Various embodiments of the systems, methods, and devices are provided for controlled operation of an intravascular lithotripsy (“IVL”) system for breaking up calcified lesions in an anatomical conduit. More specifically, control arrangements are disclosed concerning managing and / or providing and / or assessing the electrical energy needed to generate an electrical arc between a set of spaced-apart electrodes disposed within a fluid-fillable member.

The application discloses a calcification elimination system for vascular calcification lesions, and relates to the technical field of medical calcification elimination devices, which comprises a multi-cavity catheter, an ultrasonic conducting wire and a filter screen. A broken balloon is arranged on the outer wall of the multi-cavity catheter. The multi-cavity catheter comprises a suction cavity, a first filling cavity, a conducting wire cavity and a wire-retracting cavity, which all extend along the length direction. A suction hole is arranged on the distal end side wall of the suction cavity. The ultrasonic conducting wire is partially arranged in the conducting wire cavity. The proximal end of the ultrasonic conducting wire is connected with an ultrasonic energy source. The ultrasonic conducting wire has a spiral section, which is sleeved on the outside of the broken balloon. The filter screen is located on the distal end side of the broken balloon. The filter screen is connected with the distal end wall of the suction cavity. The outer edge of the filter screen is connected with a wire-retracting wire. The proximal end of the wire-retracting wire extends to the proximal end of the multi-cavity catheter through the wire-retracting cavity. The application can completely break the plaque, ensures complete breaking of the plaque and improves the breaking efficiency. In addition, the application avoids the problem of vascular thermal damage caused by the local concentration of ultrasonic energy.

The present application provides a shock wave balloon catheter device, which comprises a catheter body and a balloon connected with the distal end of the catheter body, the catheter body has a liquid passage cavity extending along the axial direction of the catheter body, and the inner cavity of the balloon is connected with the liquid passage cavity; the balloon is provided with a first shock wave emitting element for releasing axial impact wave along the axial direction of the balloon and a second shock wave emitting element for releasing radial impact wave along the radial direction of the balloon, the first shock wave emitting element and the second shock wave emitting element are electrically connected with a high-voltage generator, and the first shock wave emitting element is located in the distal end of the balloon. The shock wave balloon catheter device can release impact wave along the axial direction and the radial direction of the balloon, so as to cope with various complex calcified lesions when applied to the treatment of calcified lesions in blood vessels.

The utility model relates to a detachable papillary balloon and balloon catheter, including inner layer balloon, outer layer balloon, convex part structure, the fluid passage is formed between outer layer balloon, inner layer balloon, is provided with the hole on outer layer balloon, the convex part structure includes convex part main part, barb, drug loading membrane, the hole of outer layer balloon is blocked up with convex part main part being connected on outer layer balloon, the barb is connected on convex part main part, the drug loading membrane is coated on convex part main part and / or barb, when fluid acts on convex part main part through fluid passage, hole, convex part main part can be separated from outer layer balloon. The utility model utilizes the feature that the convex part structure is less in contact with calcified lesion or narrow site, plays the pressure amplification effect, and better expands and crushes plaque, through the separation of the convex part structure and the balloon, the separated convex part structure is anchored in the vascular intima, thereby continuously administering, short residence time, long administration duration, and better treatment effect.

A multi-modality catheter is configured to treat a calcified lesion of a body lumen. The multi-modality catheter includes an integrated intravascular lithotripsy balloon and second treatment balloon. The intravascular lithotripsy balloon includes a shock wave emitter to produce a shock wave for modifying the calcified lesion. The second treatment balloon is configured to treat the calcified lesion.

Included in the present disclosure is a medical device, including an elongated body. In some embodiments, the medical device includes a balloon positioned at a distal portion of the elongated body, the balloon configured to receive a fluid to inflate such that an exterior surface of the balloon is configured to contact an interior surface of a target treatment site within a vasculature of a patient. According to some embodiments, the balloon is configured to transition between an uninflated state and an inflated state. When the balloon is in the uninflated state, the balloon may be pleatless. In some embodiments, the medical device includes one or more pressure-wave emitters positioned along a central longitudinal axis of the elongated body within the balloon, the one or more pressure-wave emitters configured to propagate pressure waves radially outward through the fluid to fragment a calcified lesion at the target treatment site.

The present invention discloses a drug eluting stent, comprising a stent body and a plurality of thorn-shaped members, wherein the stent body has a radially compressible contracted state and a radially self-expanding expanded state for supporting a blood vessel, the plurality of thorn-shaped members are arranged on the outer surface of the stent body and coated with a drug coating for inhibiting restenosis of the blood vessel, and are configured to protrude from the outer surface of the stent body toward the outside of the stent body when the stent body switches from the contracted state to the expanded state to penetrate calcified lesions on the inner wall of the blood vessel, each thorn-shaped member comprises a spike segment, and the spike segment comprises at least a first segment and a second segment connected together at a root, the first segment and the second segment being configured to fit together to form a compact structure in a natural state, and to be elastically deformed and separated relative to the root when subjected to a reverse force from the calcified lesion, so as to achieve penetration of the calcified lesion at a larger angle, reduce the risk of slippage, improve penetration efficiency, and thereby enhance the effect of inhibiting restenosis of the blood vessel.

The application discloses a kind of coronary angiography calcification identification method, system and storage medium based on deep learning, it is related to medical cardiovascular image processing technical field.The present application comprises the following steps: the comprehensive evaluation of different blood vessel angiography projection position of the to-be-tested coronary artery;According to the CT angiography, mark the calcification lesion on the original digital subtraction angiography image independently;Using U-net neural network combined with focal loss function learning and identifying the marked calcification lesion;The U-net neural network output result is input into the LSTM network to calculate the calcification score.The present application improves the accuracy of coronary artery calcification detection and improves the prediction performance of machine learning algorithm.