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Medicament composition for curing pruritus of skin and method of preparing the same

A technology of skin itching and composition, applied in the field of new drugs, can solve problems such as large side effects, unbearable itching, and easy recurrence

Inactive Publication Date: 2008-10-08
BEIJING ZHONGKE RENHE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although skin pruritus is not a serious disease, it is unbearable and often brings great pain to patients. At present, the medicines for clinical treatment of skin pruritus are mainly external drugs, but most of them contain hormone components, which not only have large side effects, but also cannot be cured. Easy to relapse

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Prescription composition:

[0033] Sophora flavescens 120g Angelica dahurica 80g Poria cocos 80g

[0034] Danshen 80g, Gangbangui 60g, Astragalus 60g

[0035] White fresh skin 60g Cnidium 40g Phellodendron 40g

[0036] Radix Paeoniae Alba 40g Cangzhu 40g Radix Paeoniae Rubra 40g

[0037] Honeysuckle 40g Licorice 20g

[0038] A total of 1000 pieces were made

[0039] Preparation:

[0040] (1) Take Sophora flavescens, Salvia miltiorrhiza, Cortex Phellodendri, pulverize into coarse powder, use 10 times the amount of 60% ethanol to reflux extract for 3 hours, extract the alcohol solution and filter; add 8 times the amount of 60% ethanol to reflux extract for 2 hours, extract the alcohol Liquid filtration; plus 8 times the amount of 60% ethanol for reflux extraction of medicinal residues for 2 hours, extract alcohol liquid and filter; combine filtrates, recover ethanol under reduced pressure and concentrate to a clear ointment with a relative density of 1.25 (55°C), for...

Embodiment 2

[0046] Prescription composition:

[0047] Sophora flavescens 60g Angelica dahurica 40g Poria cocos 40g

[0048] Danshen 40g, Gangbangui 30g, Astragalus 30g

[0049] White fresh skin 30g Cnidium 20g Phellodendron 20g

[0050] Radix Paeoniae Alba 20g Cangzhu 20g Radix Paeoniae Rubra 20g

[0051] Honeysuckle 20g licorice 10g sucrose 940

[0052] Made a total of 1000g

[0053] Preparation:

[0054] (1) Take Sophora flavescens, Salvia miltiorrhiza, Cortex Phellodendri, pulverize into coarse powder, use 10 times the amount of 60% ethanol to reflux extract for 3 hours, extract the alcohol solution and filter; add 8 times the amount of 60% ethanol to reflux extract for 2 hours, extract the alcohol Liquid filtration; plus 8 times the amount of 60% ethanol for reflux extraction of medicinal residues for 2 hours, extract alcohol liquid and filter; combine filtrates, recover ethanol under reduced pressure and concentrate to a clear ointment with a relative density of 1.25 (55°C), for...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating pruritus cutanea and a preparation method thereof. The pharmaceutical composition is prepared by raw medicine materials with the following mixing ratio by weight: 10 to 50 parts by weight of sophora flavescens, 10 to 30 parts by weight of angelica dahurica, 10 to 20 parts by weight of poris cocos, 10 to 20 parts by weight of salvia miltiorrhiza, 10 to 20 parts by weight of polygonum perfoliatum, 10 to 20 parts by weight of radix astragali, 10 to 20 parts by weight of root bark of shaggy-fruited dittany, 10 to 20 parts by weight of fructus cnidii fruit, 5 to 10 parts by weight of corktree, 5 to 10 parts by weight of root of white herbaceous peony, 5 to 10 parts by weight of rhizoma atractylodis, 5 to 10 parts by weight of root of red herbaceous peony, 5 to 10 parts by weight of honey suckle and 5 to 10 parts by weight of licorice. The pharmaceutical composition has the functions of removing internal heating, dispersing pathogenic wind, detoxification and activating blood circulation to dissipate blood stasis and is applicable to pruritus cutanea caused by various reasons and has good efficacy.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for treating skin pruritus and a preparation method thereof, belonging to the technical field of new medicines. Background technique [0002] Skin pruritus is a kind of skin disease with pruritus as the main clinical symptom, but no primary rash, which is called wind pruritus in traditional Chinese medicine. The main manifestations are generalized or localized itching (mostly in the anus, scrotum, and vulva). The itching is often paroxysmal. Long-term itching can cause symptoms of neurasthenia such as dizziness, depression, and loss of appetite. [0003] Pruritus is one of the common skin diseases in clinical practice. Its causes are complex and there are many pathogenic factors. [0004] Although skin pruritus is not a serious disease, itching is unbearable and often brings great pain to patients. At present, the medic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P17/04
Inventor 颜丽君
Owner BEIJING ZHONGKE RENHE SCI & TECH
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