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Biological and adsorbable bone internal fixation implantation instrument

A bioactive and fixed device technology, which is applied in the field of biomedical devices, orthopedic trauma surgery, medical devices for plastic surgery, repair and reconstruction surgery, can solve the problems of low bioactivity and no bioactivity, and achieve low elastic modulus, The effect of avoiding stress shielding effect and excellent mechanical properties

Inactive Publication Date: 2008-10-15
INST OF METAL RESEARCH - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention aims to solve the problem of low bioactivity or no bioactivity of current absorbable bone fixation products for bone fixation, and proposes a bioactive absorbable magnesium alloy bone fixation implant device

Method used

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  • Biological and adsorbable bone internal fixation implantation instrument
  • Biological and adsorbable bone internal fixation implantation instrument
  • Biological and adsorbable bone internal fixation implantation instrument

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Such as figure 1 As shown, the bone plate 1 and the bone screw 3 are made of AZ31B (magnesium-aluminum series) magnesium alloy. Such as figure 2 As shown, after soaking in simulated body fluid for 3 days, a Ca-P layer was deposited on the surface, indicating that the bone plate and screw have good biological activity. One month after implantation in the animal body, there was a large amount of new tissue surrounding the bone plate, while the new tissue around the titanium alloy bone plate was relatively small, and the bone plate could not be wrapped. It is proved that the magnesium alloy bone plate has excellent biological activity.

Embodiment 2

[0033] Such as Figure 3-12 As shown, the ZK60 (magnesium-zinc series) magnesium alloy was made into L-shaped, T-shaped, trilobal, Y-shaped, special-shaped, arc-shaped, S-shaped bone plates and bone nails and soaked in simulated body fluid for 3 days. The deposition of Ca P layer shows that the bone plate has good biological activity.

Embodiment 3

[0035] Intramedullary nails were processed from AM60 (magnesium-aluminum series) magnesium alloy. After polishing, they were ultrasonically cleaned in acetone and alcohol for 5 minutes, dried in a vacuum oven, and then sprayed on the surface of the magnesium alloy bone plate by thermal spraying. The apatite layer with a thickness of 5 μm further improves the osteoinductive performance of the intramedullary nail.

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Abstract

The invention relates to a bone implanting and internal fixation appliance with bioactivity and absorbability, which belongs to the field of bio-medical appliances, particularly to the field of medical appliances used for bone wound surgery, reparative and reconstructive surgery and plastic and cosmetic surgery. The appliance includes bone nails and a bone plate made of magnesium and the alloy thereof with bioactivity and absorbability. The bone implanting and internal fixation appliance is a bone internal fixation device, which comprises a blade plate and matched screws, intramedullary nails, a fracture and dislocation fixing device of vertebral column, bone nails or screws having individual fixation effect, wherein the bone internal fixation device is made of magnesium and the alloy thereof with bioactivity and absorbability. The bone internal fixation device can solve the problem in bioactivity of prior bone internal fixation device and promote healing the tissue where the device in implanted. The device also includes a protection layer prepared on the surface of the internal fixation device for controlling the degradation rate of magnesium alloy and the dissolution rate of magnesium ions, thus controlling the bioactivity and the absorption speed of the magnesium alloy device in an organism.

Description

technical field [0001] The invention relates to an orthopedic internal fixation device in a medical device, which belongs to the field of biomedical devices, and is especially suitable for the field of orthopedic trauma surgery, repair and reconstruction surgery, and plastic surgery; specifically, a bioactive absorbable bone internal fixation implant device, It is a bone nail and bone plate medical device made of bioactive and absorbable metal magnesium and its alloys. Background technique [0002] Bioactivity is a property that can enhance cell activity or regeneration of new tissue, and is an important indicator in bone implant devices. The bioactive bone implant device can promote the proliferation and differentiation of surrounding osteoblasts after implantation into the organism, accelerate the regeneration of new tissue, and reduce the healing time of damaged bone tissue; at the same time, it can form a chemical bond with the surrounding tissue Or called osseointegrat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B17/68A61L27/04A61L27/58A61L31/14
Inventor 谭丽丽任伊宾杨柯张炳春肖克沈郑丰
Owner INST OF METAL RESEARCH - CHINESE ACAD OF SCI
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