35results about How to "Avoid stress shielding effects" patented technology

The invention relates to a bone implanting and internal fixation appliance with bioactivity and absorbability, which belongs to the field of bio-medical appliances, particularly to the field of medical appliances used for bone wound surgery, reparative and reconstructive surgery and plastic and cosmetic surgery. The appliance includes bone nails and a bone plate made of magnesium and the alloy thereof with bioactivity and absorbability. The bone implanting and internal fixation appliance is a bone internal fixation device, which comprises a blade plate and matched screws, intramedullary nails, a fracture and dislocation fixing device of vertebral column, bone nails or screws having individual fixation effect, wherein the bone internal fixation device is made of magnesium and the alloy thereof with bioactivity and absorbability. The bone internal fixation device can solve the problem in bioactivity of prior bone internal fixation device and promote healing the tissue where the device in implanted. The device also includes a protection layer prepared on the surface of the internal fixation device for controlling the degradation rate of magnesium alloy and the dissolution rate of magnesium ions, thus controlling the bioactivity and the absorption speed of the magnesium alloy device in an organism.

The present invention relates to biomedicine metal implant material, and is especially metal implant material with controllable erosion and degrading rate and its application. The metal implant material with controllable erosion and degrading rate is magnesium or magnesium alloy with poor anticorrosive property. The metal implant material with controllable erosion and degrading rate of magnesium or magnesium alloy may be used in preparing temporary or short term implanted device, such as degradable blood rack and peripheral rack, bone fracture plate and bone nail for inner fixing, tissue engineering rack, etc.

The invention provides a photothermal bone repair material. The photothermal bone repair material consists of a synthetic polymer and metal/metal oxide particles, wherein the metal/metal oxide particles are selected from one of magnesium metal particles, aluminum metal nanometer particles, aluminum oxide nanometer particles, ferrum metal particles, ferric oxide nanometer particles and ferroferricoxide nanometer particles. The photothermal bone repair material provided by the invention has photothermal properties of high light absorption efficiency and high photothermal conversion efficiency,after the photothermal bone repair material is implanted into an tumor nidus excision postoperative position, postoperative osteanagenesis can be promoted, besides, peripheral tumor tissue and potential small niduses are subjected to radical cure, and effects of osteogenesis and treatment are achieved.

The invention relates to a bone-like porous biomechanical bionic design spine fusion device and its preparation method and application, which belong to the field of biomedical materials and are composed of a plurality of microporous spatial structural units, the microporous spatial structural unit is a regular tetrahedral structure, and the microporous The spatial structure unit body includes a base point and a filling geometry; the base point is located at the apex of the front tetrahedron; the filling geometry is arranged at the position of the base point, and the filling geometry intersects with the adjacent filling geometry to form a regular tetrahedral edge, and multiple microporous spatial structure units The shape, size and porosity of the pores of the material can be precisely adjusted to achieve the mechanical properties of natural bone matching. performance, and can be customized according to the needs of patients, with good biocompatibility, bioactivity, and biomechanical suitability, and has broad application prospects in orthopedic clinics.

The invention discloses a multistage through-hole porous tooth implantation body. The multistage through-hole porous tooth implantation body comprises a gingiva passing through segment and a screw thread segment; the gingiva passing through segment is of a smooth solid structure, and is arranged on the upper part of the screw thread segment; the multistage through-hole porous tooth implantation body also comprises a porous structure segment; the porous structure segment is arranged on the lower part of the screw thread segment; the hole diameter of transverse through holes on the porous structure segment from the lower part to the upper part is increased successively; the transverse through holes with the same hole diameter are arranged in a radiation manner along the periphery of the porous structure segment. The multistage through-hole porous tooth implantation body is capable of increasing combination strength, increasing combination speed, and is provided with the porous structure conveniently.

The invention relates to a method for forming a composite rhBMP-2 elasticity modulus graded porous titanium alloy support rod for the femoral head and the neck. Titanium alloy powder is prepared with an electrode induction melting gas atomization method, and the integrated elasticity modulus graded porous titanium alloy support rod consisting of a head part, a body part and a tail part is prepared according to actually measured biomechanical parameters of the femoral head, the neck and a rotor, wherein the head part and the body part are prepared by sintering the titanium alloy powder and pore-forming agents through the adoption of a cold rolling method, the tail part is prepared by directly sintering the titanium alloy powder, and the porous titanium alloy support rod is immersed in a rhBMP-2/gelatin controlled release microsphere solution. The product prepared by the method can simulate the biomechanical properties of the femoral head and the neck of a human body to the utmost extent, thereby being beneficial to the stress transfer between materials and bone tissue interfaces, avoiding poor bone restoration caused by the stress shielding effect; and simultaneously, sustained-release microspheres on which bone induced growth factors (rhBMP-2) are loaded endue the materials per se with good bone conductivity.

The invention relates to a preparation method for a controllable degradation type zinc-magnesium gradient material, belongs to the technical field of preparation and application of medical biomaterials. According to the preparation method, the problem that a single homogeneous material can hardly meet the application requirement of the diversity of a degradable implant material can be solved, magnesium powder and zinc powder serve as raw materials, and the controllable degradation type zinc-magnesium gradient material is developed through a preparation technology of powder preparation, ball-milling and powder mixing, powder laying, pre-pressing forming and spark plasma sintering; the density of the material is 3.58 g/cm<3>, the compactness reaches 98.2%, the compressive strength is about 261 MPa, the bending strength is 114 MPa, the bending modulus is 7.1 GPa, the material is matched with bone tissue of a human body in performance, the stress shielding effect can be effectively avoided, and the performance requirement of a hard tissue implant of the human body can be met; and meanwhile, the gradient material is soaked and corroded, has good corrosion resistance at the early stage and has the characteristic of obviously increased corrosion rate in the later stage, and the unique functional requirements that the outer layer material is corrosion-resistant at the initial stage ofimplantation, can ensure the mechanical property and is rapidly degraded in the later stage of implantation can be met.

The invention discloses a biomedical metal porous coating capable of replacing bone cement and a preparation method of the biomedical metal porous coating. Metal powder is laid on the surface of a metal-based implant, and the metal porous coating is formed on the surface of the metal-based implant through spark plasma vacuum sintering. The metal porous coating meets specific pore characteristics and performance indexes required by bone tissue ingrowth, is well combined with the metal-based implant, and can be used instead of the bone cement, so that bone tissue can enter the metal porous coating along with bone growth, effective combination with the metal-based implant is facilitated, and a series of negative influences caused by using the existing bone cement are avoided. The preparation temperature of the metal porous coating is relatively low, a pore forming agent is not used, the preparation period is short, and operation is easy.