Medicament composition for treating otitis medium and preparation thereof

A composition and technology for otitis media, applied in the directions of drug combinations, pharmaceutical formulations, active ingredients of hydroxyl compounds, etc., can solve the problems of ineffective chemical antibiotic ear drops, direct toxicity of the inner ear, affecting hearing, etc. Sexuality, no obvious side effects, and the effect of a short course of treatment

Active Publication Date: 2008-10-29
SICHUAN KELUN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the wide application of various antibiotics and the increase of drug-resistant strains, the effect of chemical antibiotic ear drops is not obvious. Some aminoglycoside antibiotics have direct toxic effects on the inner ear, damage the cochlea, and

Method used

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  • Medicament composition for treating otitis medium and preparation thereof
  • Medicament composition for treating otitis medium and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] Embodiment 1: Preparation of ear drops

[0083] Coptis 200g, borneol 50g, dry alum 150g, alum 30g, keel 15g, sea octopus 15g

[0084] Take coptis, borneol, dry alum, alum, keel, and sea octopus, and grind them separately, mix the coptis, keel, and sea octopus, add 1000ml of 60% ethanol to soak for 10 days, stir once a day, 30 minutes each time, Pour out the supernatant, filter, squeeze the residue, combine the squeezed liquid with the filtrate and the supernatant; let stand for 24 hours, filter, add alum, dry alum, borneol to the filtrate, add 20ml of benzyl alcohol after dissolving, and then add 60% ethanol to 1000ml, mix well, and get ready.

Embodiment 2

[0085] Embodiment 2: the preparation of ear drops

[0086] Coptis 100g, borneol 50g, dry alum 300g, alum 50g, keel 5g, sea octopus 30g

[0087] Take coptis, borneol, dry alum, alum, keel, and sea octopus, and grind them separately, mix the coptis, keel, and sea octopus, add 500ml of 40% ethanol to soak for 2 days, stir 3 times a day, 60 minutes each time, Pour out the supernatant, filter, squeeze the residue, combine the squeezed liquid with the filtrate and the supernatant; let stand for 6 hours, filter, add alum, dry alum, borneol to the filtrate, add 50ml of benzyl alcohol after dissolving, and then add 40% ethanol to 1000ml, mix well, and get ready.

Embodiment 3

[0088] Embodiment 3: Preparation of ear drops

[0089] Coptidis 300g, borneol 100g, dry alum 100g, alum 20g, keel 15g, sea octopus 30g

[0090] Take coptis, borneol, dry alum, alum, keel, and sea octopus, and grind them separately, mix the coptis, keel, and sea octopus, add 2000ml of 80% ethanol to impregnate, impregnate for 20 days, stir twice a day, 20 minutes each time, Pour out the supernatant, filter, squeeze the residue, combine the squeezed liquid with the filtrate and the supernatant; let stand for 72 hours, filter, add alum, dry alum, borneol to the filtrate, add 10ml of benzyl alcohol after dissolving, and then add 80% ethanol to 1000ml, mix well, and get ready.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine compound medicine composition for treating otitis media and a preparation process thereof. The traditional Chinese medicine compound medicine composition for treating otitis media is mainly composed of golden thread, borneol, calcined alum, alum, fossilized and cuttlebone. The ear drops are characterized by rapid dry ear, high efficacy, short course of treatment, no significant side effects, safe medication and so on.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating otitis media and a preparation process thereof, in particular to a pharmaceutical composition for treating acute, chronic and suppurative otitis media and a preparation process thereof. Background technique [0002] Acute, chronic, and suppurative otitis media are common and frequently-occurring diseases in otology clinics. People's Liberation Army Navy, Air Force, coastal fishermen and swimming enthusiasts are very prone to ear canal diseases, especially children. According to the survey of 1,000 children aged 2-14 in the UK, suppurative otitis media accounted for 8% of newly diagnosed patients in ENT department, and domestic statistics accounted for 11.7% of newly diagnosed patients in ENT department. The bacteria that are susceptible to infection are diverse. Due to the wide application of various antibiotics and the increase of drug-resistant strains, the effect of chemical antibiot...

Claims

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Application Information

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IPC IPC(8): A61K36/718A61K9/10A61P27/16A61K31/045A61K35/56A61K35/02A61K33/06A61K35/618
Inventor 王利春梁隆程志鹏
Owner SICHUAN KELUN PHARMA CO LTD
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