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Sucrose absorption inhibitor

A monosaccharide and arabinose technology, applied in the field of sucrose absorption inhibitors, can solve problems such as affecting the quality of life, and achieve the effect of reducing the preparation cost

Inactive Publication Date: 2008-12-10
CHINA FUEL HUAIBEI BIOENERGY TECH DEV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since most people have developed the habit of eating sucrose during their growth, once they have to avoid it due to reasons such as overweight, obesity, high blood sugar and diabetes, it will seriously affect the quality of life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] Synthesis of Example 1 Arabinose Trace Element Complex

[0079] A: Use pure arabinose as raw material

[0080] Under the protection of nitrogen, 1.0 mole of arabinose was dissolved in 10 liters of pure water under the condition of stirring at room temperature and pressure, and then the pre-prepared calcium acetate aqueous solution (1.0 mole of calcium acetate was dissolved in 5 liters of pure water) was stirred Add it all to the arabinose solution. Continue to stir for an hour after adding the calcium acetate aqueous solution, add 200 grams of activated carbon for decolorization, add 95% ethanol to the clear liquid after filtering the activated carbon, stop adding ethanol after no precipitation occurs, let it stand for 30 minutes, filter and vacuum After drying, 293 g of a white solid product was obtained, with a yield of 95%. The obtained white solid was recrystallized with food-grade absolute ethanol to obtain a white crystal product.

[0081] 1 H-NMR (ppm, CD 3 ...

Embodiment 2

[0088] Embodiment 2, preparation L-arabinose

[0089] Take by weighing 100 kg of crushed corn bran, boil it with 80° C. hot water for 10 minutes to remove wax, starch, and volatile components. After plate and frame filtration to remove liquid, use pure water to prepare biomimetic catalyst CpFeCO(maleic acid)]BF containing 1% by weight 4 , The solid-liquid ratio of the mixture is 10:1, catalytic hydrolysis in a closed container at a temperature of 121 ° C for 65 minutes, cooled to a temperature < 35 ° C plate and frame filter to filter out insoluble matter. The filter cake was washed twice with water, and the water consumption for each washing was 100 L. After the liquids were combined and the biomimetic catalyst was separated, activated carbon with a mass percent of the filtrate was added, decolorized at 100° C. for 45 minutes, and plate and frame filtered. The obtained filtrate passes through 732 cation exchange resin——721 anion exchange resin——732 cation exchange resin col...

Embodiment 3

[0090] Embodiment 3: Calcium arabinose is used for treating (or improving) diabetes.

[0091] Eighteen non-insulin-dependent diabetes model Winstar rats, male, 8 weeks old (200-220 grams of body weight), which showed hyperglycemia (260-280 mg / liter), were fed for 1 week in advance, and were divided into three groups (group A , B, and C) for testing. Place each mouse individually in a plastic cage at 23±1°C under a 12-hour light-dark cycle (from 7 am to 7 pm in a light environment, and from 7 pm to 7 am the next day in a dark environment) Raising, the mice had free access to food and water. Blood was collected from the tail vein of the rats at 9 o'clock in the morning, and blood glucose levels were measured by the glucose oxidase method. Add 20% by weight of sucrose in the food of group A, add 20% by weight of sucrose and 2% arabinose calcium in the food of group B, add 20% by weight of sucrose and 2% arabinose by weight in the food of group C ( Purity 97.6%), fed altogether...

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PUM

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Abstract

The present invention discloses a fire-new sucrose absorbing depressor, which is the common microelement complex in arabinose and living body. No matter the complex is pure compound or mixture containing other natural products, the pure compound and the mixture has equal effect. The complex can be used for reducing glycemia, losing weight and other purposes. A simpler arabinose separation method is also provided by the present invention.

Description

technical field [0001] The invention is a brand-new sucrose absorption inhibitor, more precisely, the sucrose absorption inhibitor used to inhibit the absorption of sucrose in the body, and the active ingredient is arabinose trace element complex. Background technique [0002] Although most of the absorbable sugar contained in food is starch, due to people's preference for refined food, sucrose and other disaccharides are easy to obtain and low in price, making sucrose a very preferred sweet food by human beings. Widely used and ingested in large quantities. Although WHO has been encouraging people's daily intake of sugar to be controlled at 10% of the daily calorie requirement, that is, 50 grams per day, but due to the strong opposition of the sugar industry and only in favor of controlling it at 25%, the problem of overweight and obesity In economically developed countries such as Europe and the United States, more than 55% of the population is troubled, and the incidence...

Claims

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Application Information

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IPC IPC(8): A61K31/7004A61K31/7135A61P3/10A23L1/304A23L1/30A23L2/52A23L33/165
Inventor 孙萌叶红平朱作霖苏春高
Owner CHINA FUEL HUAIBEI BIOENERGY TECH DEV
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