Application of terazosin for preparing medicines for treating postpartum urinary retention

A technology for postpartum urinary retention and terazosin, which is applied in drug combinations, pharmaceutical formulas, and diseases of the urinary system to achieve the effects of reducing urethral resistance, eliminating local edema, and facilitating administration

Inactive Publication Date: 2009-06-03
孙少芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the application to postpartum urinary retention has not been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] For the pharmacological effects of terazosin, we applied terazosin 1-2mg / time / day to treat patients with postpartum urinary retention, and studied its clinical efficacy.

[0008] The clinical experiment observation of medicine of the present invention:

[0009] (1) Observation objects: Among the 2,600 vaginal delivery women from January 2002 to October 2005, 68 had different degrees of postpartum urinary retention. Weight 3400-4200g, age 25-31 years old, average age 27 years old, all underwent left episiotomy, no postpartum hemorrhage and bladder, urethral tear. There was no normal urination 8 hours after delivery, the fundus of the bladder was located between the umbilicus and pubic region, and treatment such as drainage failed.

[0010] (2) Oral administration of terazosin 2mg / time / day, initial dose 1mg / time / day, in order to consolidate the curative effect, take it for 2-3 days. It is not clear whether Intrazosin is secreted in breast milk, so it is recommended to s...

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Abstract

The invention belongs to the technical field of novel application of medicines, in particular to application of terazosin for preparing medicines for treating postpartum urinary retention, and has the advantages that the terazosin is applied to the preparation of medicines for treating postpartum urinary retention, which is convenient to administer, has less adverse effect and can rapidly and effectively relieve a patient's pain.

Description

technical field [0001] The invention relates to the application of terazosin in the preparation of medicines for treating postpartum urinary retention, and belongs to the technical field of new uses of medicines. Background technique [0002] Normal puerpera should urinate automatically within 4 to 6 hours after delivery. If they cannot urinate (except anuria) after 8 hours after delivery, it is postpartum urinary retention. Mainly due to prolonged labor, the fetal presentation oppresses the bladder for too long, which reduces the tension and sensitivity of the bladder, and even nerve paralysis makes the bladder voiding reflex disappear. Congestion and edema of the bladder mucosa, and excessive elongation of the lower uterine segment, causing congestion, edema, (even bleeding) and urethral edema at the bottom of the bladder (triangle), resulting in urethral spasm, urethral orifice occlusion, and urinary retention. Postpartum urinary retention is one of the common postpartum...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/517A61P15/00A61P13/06
Inventor 孙少芳孙冰张静川杨媛媛贾俊荣张光军梁霞
Owner 孙少芳
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