Method for preparing mucosal graft

A technology of grafts and mucosa, applied in the field of medicine and biomedical engineering, can solve the problem of limited source of stem cells
CN101444645AInactive Publication Date: 2009-06-03SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
Publication Date
2009-06-03
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses an application of oral mucosa epithelia, comprising (1) preparing the graft for organ transplantation or (2) being used as seed cells to prepare mucosal grafts. The invention also discloses an application of graft which can be used for preparing the organ transplantation for repairing mucosa damage.
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Description

technical field

[0001] The invention relates to the fields of medicine and biomedical engineering, and more specifically relates to the construction of tissue-engineered mucous membrane using oral mucosal epithelial cells (OKC) and its preparation method and application. Background technique

[0002] Bladder (urinary bladder) disease is very common clinically, including bladder tumor, inflammation, tuberculosis, congenital malformation, neurogenic bladder, iatrogenic injury and other etiologies, which can cause bladder dysfunction or produce large area of ​​bladder after treatment defect. At present, the gastrointestinal tract is often used in clinical practice for replacement or bladder expansion after total bladder surgery. The continuous improvement of various surgical methods has also made the gastrointestinal tract the first choice for clinical bladder replacement so far. However, this traditional surgical repair method has " Defects such as tearing down the east wall ...

Claims

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